QuickView for CBX;jsessionid=C90FEA561EE7F868394684DE31BD3175;jsessionid=83E6504F42997CD31D167B30B0D536BE (gene)
- Gene Symbol:
- AKTIP
Homo sapiens - Full name:
- AKT interacting protein
- Synonyms:
- FT1, FTS, AKT-interacting protein, fused toes homolog
- Genomic Location:
- Chr 16: 52082693-52094671
- Description:
-
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
16q12.2
GO Molecular Function
catalytic activity | ubiquitin-like protein transferase activity | protein binding | transferase activity
GO Biological Process
establishment of localization | positive regulation of phosphate metabolic process | intracellular transport | cellular process | localization | protein transport | macromolecule localization | endomembrane system organization | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | regulation of binding | cytosolic transport | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of protein binding | lysosomal transport | positive regulation of protein metabolic process | vacuolar transport | programmed cell death | cellular localization | protein modification process | macromolecule modification | apoptotic process | nitrogen compound metabolic process | regulation of phosphorylation | early endosome to late endosome transport | endosome to lysosome transport | organic substance transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | peptide transport | vesicle-mediated transport | regulation of cellular protein metabolic process | vacuole organization | regulation of cellular metabolic process | lysosome organization | regulation of protein metabolic process | regulation of protein phosphorylation | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | protein ubiquitination | metabolic process | amide transport | organic substance metabolic process | cell death | protein modification by small protein conjugation or removal | regulation of phosphate metabolic process | positive regulation of binding | establishment of protein localization | vesicle organization | regulation of protein binding | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | endosome organization | organelle organization | cellular protein modification process | positive regulation of metabolic process | cellular metabolic process | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
cell | HOPS complex | tethering complex | cytoplasm | protein-containing complex | plasma membrane | cell periphery | cytosol | intracellular | membrane | FHF complex
