QuickView for CD31;jsessionid=6BF8D72469EF0C11A8188D0F5ECA8336;jsessionid=5CB50597B151E7EF5C8D87BB9C7BD97C (gene)
- Gene Symbol:
- Pecam1
Rattus norvegicus - Full name:
- platelet and endothelial cell adhesion molecule 1
- Synonyms:
- CD31, Pecam, platelet endothelial cell adhesion molecule, PECAM-1, platelet/endothelial cell adhesion molecule 1
- Genomic Location:
- N/A
- Description:
-
cell adhesion molecule, also intracellular signaling molecule; may mediate leukocyte adhesion and migration, angiogenesis, and thrombosis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Pan troglodytes , Danio rerio , Canis lupus familiaris , Gallus gallus
- External Links:
- Entrez Gene
GO Molecular Function
enzyme binding | identical protein binding | protein binding | protein homodimerization activity | protein phosphatase binding | protein dimerization activity | phosphatase binding
GO Biological Process
negative regulation of phosphorylation | regulation of supramolecular fiber organization | cell morphogenesis | positive regulation of locomotion | diapedesis | response to cytokine | neutrophil extravasation | cell motility | intracellular signal transduction | endothelial cell development | regulation of localization | cell-substrate adhesion | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | regulation of immune system process | negative regulation of cellular process | cell differentiation | endothelial cell differentiation | defense response | glomerulus development | negative regulation of protein phosphorylation | epithelial cell migration | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | blood vessel morphogenesis | cellular process | regulation of cell motility | localization | epithelium migration | response to growth factor | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | regulation of cellular extravasation | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | response to transforming growth factor beta | urogenital system development | cellular response to interferon-gamma | regulation of actin filament length | response to stimulus | vasculature development | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | positive regulation of JAK-STAT cascade | endothelial cell migration | tube morphogenesis | epithelial cell development | cardiovascular system development | cellular response to organic cyclic compound | negative regulation of metabolic process | regulation of cellular component size | kidney development | epithelial cell morphogenesis | blood vessel development | leukocyte migration | locomotion | system development | regulation of signal transduction | endothelium development | negative regulation of phosphate metabolic process | regulation of actin cytoskeleton organization | multicellular organism development | negative regulation of catalytic activity | cell migration | glomerulus vasculature development | regulation of actin filament organization | regulation of catalytic activity | regulation of phosphorylation | wound healing | kidney epithelium development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of actin filament polymerization | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | vesicle-mediated transport | regulation of cellular component movement | endothelial cell-matrix adhesion | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | angiogenesis | regulation of GTPase activity | cell morphogenesis involved in differentiation | regulation of leukocyte migration | positive regulation of cellular extravasation | cell communication | regulation of cellular metabolic process | regulation of actin filament polymerization | positive regulation of tyrosine phosphorylation of STAT protein | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of locomotion | renal system development | nephron development | cellular response to transforming growth factor beta stimulus | negative regulation of protein polymerization | positive regulation of protein modification process | response to organic substance | Rho protein signal transduction | glomerular endothelium development | regulation of JAK-STAT cascade | response to wounding | import into cell | regulation of intracellular signal transduction | anatomical structure development | leukocyte cell-cell adhesion | negative regulation of cytoskeleton organization | endocytosis | cell adhesion | immune response | negative regulation of protein complex assembly | animal organ development | negative regulation of cellular protein metabolic process | positive regulation of leukocyte migration | regulation of phosphate metabolic process | cell-cell adhesion | response to interferon-gamma | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | signaling | cell-matrix adhesion | response to organic cyclic compound | cell development | negative regulation of peptidyl-tyrosine phosphorylation | positive regulation of phosphorylation | anatomical structure morphogenesis | developmental process | cellular extravasation | tube development | innate immune response | Ras protein signal transduction | negative regulation of GTPase activity | epithelial cell differentiation | negative regulation of supramolecular fiber organization | negative regulation of hydrolase activity | cell-cell adhesion via plasma-membrane adhesion molecules | positive regulation of metabolic process | regulation of actin filament-based process | immune system process | ameboidal-type cell migration | cellular response to organic substance | endothelial cell morphogenesis | positive regulation of cell motility | neutrophil migration | circulatory system development | glomerular epithelium development | phagocytosis | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | homophilic cell adhesion via plasma membrane adhesion molecules | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | integral component of membrane | ruffle | cell | intrinsic component of membrane | smooth muscle contractile fiber | external side of plasma membrane | cytoplasm | intracellular organelle | membrane microdomain | contractile fiber | cell projection | plasma membrane | cell leading edge | membrane raft | extracellular region | organelle | extracellular space | cell periphery | cell surface | intracellular | cell junction | membrane | supramolecular complex
