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QuickView for CD46;jsessionid=91CAD0D3F40745BF7D902AC3DB704AE8;jsessionid=70DCB3E7BADEEB69070BD6BF797298BB (gene)


Gene Symbol:
Cd46 Rattus norvegicus Rattus norvegicus
Full name:
CD46 molecule
Synonyms:
Mcp, membrane cofactor protein, CD46 antigen, complement regulatory protein, CD46 molecule, complement regulatory protein
Genomic Location:
Chr 13: 110972812-111003407
Description:
may be involved in fertilization or reproduction; human homolog acts as an inhibitor of plasma membrane complement
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene


Transcripts Names
NM_019190
XM_008769849
XM_006250478
Protein Names
Q9Z0M4



GO Molecular Function

cadherin binding | complement binding | enzyme inhibitor activity | hydrolase activity | molecular function regulator | catalytic activity | cell adhesion molecule binding | protein binding | endopeptidase activity | enzyme regulator activity | peptidase activity

GO Biological Process

positive regulation of immune response | adaptive immune response | negative regulation of immune system process | negative regulation of complement activation | proteolysis | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of lymphocyte activation | regulation of T cell differentiation | positive regulation of cell adhesion | negative regulation of proteolysis | positive regulation of T cell differentiation | negative regulation of signaling | positive regulation of immune effector process | positive regulation of memory T cell differentiation | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of immune response | regulation of cellular process | regulation of metabolic process | response to stimulus | enzyme inhibitor activity | regulation of regulatory T cell differentiation | positive regulation of immune system process | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of cell-cell adhesion | regulation of humoral immune response | positive regulation of cell activation | reproduction | positive regulation of T cell activation | negative regulation of metabolic process | regulation of protein processing | regulation of cell adhesion | molecular function regulator | regulation of lymphocyte differentiation | positive regulation of mononuclear cell proliferation | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of catalytic activity | positive regulation of lymphocyte differentiation | leukocyte mediated immunity | regulation of catalytic activity | regulation of acute inflammatory response | regulation of T cell activation | regulation of gene expression | extracellular negative regulation of signal transduction | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | regulation of Notch signaling pathway | sequestering of extracellular ligand from receptor | positive regulation of cell differentiation | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | negative regulation of immune response | fertilization | regulation of complement activation | interleukin-10 production | regulation of cellular metabolic process | T cell mediated immunity | negative regulation of protein processing | regulation of protein metabolic process | positive regulation of cell proliferation | single fertilization | cytokine production | positive regulation of transforming growth factor beta production | protein metabolic process | regulation of hemopoiesis | metabolic process | positive regulation of leukocyte activation | immune response | organic substance metabolic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | regulation of cell activation | positive regulation of cytokine production | negative regulation of protein metabolic process | regulation of cell communication | positive regulation of interleukin-10 production | negative regulation of molecular function | negative regulation of signal transduction | endopeptidase activity | regulation of T cell proliferation | enzyme regulator activity | regulation of cytokine production | positive regulation of regulatory T cell differentiation | regulation of developmental process | regulation of cell-cell adhesion | positive regulation of metabolic process | immune system process | peptidase activity | regulation of inflammatory response | sexual reproduction | positive regulation of leukocyte cell-cell adhesion | regulation of memory T cell differentiation | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

secretory granule | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | acrosomal vesicle | intracellular organelle | inner acrosomal membrane | secretory granule membrane | Golgi apparatus | secretory vesicle | endomembrane system | plasma membrane | vesicle | acrosomal membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | basolateral plasma membrane | intracellular vesicle | cell surface | intracellular | membrane | cytoplasmic vesicle membrane