QuickView for CD54;jsessionid=AA5A151B597E810C0C120F397571A18E;jsessionid=A7A695DF7399DCE70BDABAD0B87110E5 (gene)
- Gene Symbol:
- Icam1
Mus musculus - Full name:
- intercellular adhesion molecule 1
- Synonyms:
- CD54, Icam-1, Ly-47, MALA-2, intercellular adhesion molecule 1, myD10
- Genomic Location:
- Chr 9: 20820404-20833241
- Description:
-
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1. It participates in the innate immune response.
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFKAPPAB65_01 , CREL_01 , NFKAPPAB_01 , IK1_01 , NFKB_Q6 , NFKB_C , STAT_01 , STAT3_01 , STAT5A_01 , STAT5B_01
GO Molecular Function
protein-containing complex binding | signaling receptor binding | integrin binding | cell adhesion molecule binding | protein binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | regulation of supramolecular fiber organization | adaptive immune response | regulation of blood vessel diameter | positive regulation of locomotion | positive regulation of leukocyte adhesion to vascular endothelial cell | positive regulation of blood circulation | response to cytokine | cellular response to glucose stimulus | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | antigen processing and presentation | developmental process involved in reproduction | endothelial cell development | regulation of localization | positive regulation of DNA-binding transcription factor activity | gonad development | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | T cell antigen processing and presentation | regulation of immune system process | regulation of nitric oxide biosynthetic process | regulation of cell shape | negative regulation of cellular process | cell differentiation | endothelial cell differentiation | defense response | cellular chemical homeostasis | glucose homeostasis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | sensory perception of mechanical stimulus | virion attachment to host cell | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | positive regulation of actin filament polymerization | regulation of cell motility | localization | cellular homeostasis | T cell extravasation | negative regulation of signaling | positive regulation of reactive oxygen species metabolic process | reproductive system development | negative regulation of apoptotic process | Sertoli cell differentiation | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | tissue development | interspecies interaction between organisms | positive regulation of vasoconstriction | negative regulation of apoptotic signaling pathway | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | regulation of cellular extravasation | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | viral life cycle | T cell activation | regulation of actin filament length | development of primary sexual characteristics | response to stimulus | negative regulation of epithelial cell apoptotic process | regulation of peptidyl-tyrosine phosphorylation | positive regulation of nitric oxide metabolic process | positive regulation of immune system process | positive regulation of protein metabolic process | cell adhesion mediated by integrin | regulation of blood vessel size | response to stress | leukocyte activation involved in immune response | regulation of blood circulation | positive regulation of cell-cell adhesion | epithelial cell development | response to glucose | inflammatory response to antigenic stimulus | reproduction | negative regulation of transport | blood circulation | regulation of cellular component size | regulation of cell adhesion | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | leukocyte migration | regulation of nucleic acid-templated transcription | regulation of neurotransmitter levels | locomotion | positive regulation of reactive oxygen species biosynthetic process | regulation of cell projection assembly | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | system development | reproductive process | regulation of signal transduction | positive regulation of organelle organization | endothelium development | regulation of actin cytoskeleton organization | multicellular organism development | cell migration | cellular glucose homeostasis | regulation of MAPK cascade | regulation of actin filament organization | leukocyte mediated immunity | regulation of catalytic activity | regulation of phosphorylation | adhesion of symbiont to host | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | nervous system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | establishment of endothelial barrier | regulation of nitrogen compound metabolic process | regulation of cell migration | lymphocyte migration | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | regulation of cellular component movement | regulation of endothelial cell apoptotic process | positive regulation of hydrolase activity | negative regulation of extrinsic apoptotic signaling pathway | positive regulation of cell migration | cellular response to cytokine stimulus | receptor-mediated virion attachment to host cell | regulation of cellular protein metabolic process | T cell activation involved in immune response | negative regulation of ion transport | regulation of GTPase activity | regulation of apoptotic signaling pathway | regulation of epithelial cell apoptotic process | regulation of leukocyte migration | positive regulation of cellular extravasation | regulation of cellular metabolic process | regulation of actin filament polymerization | inflammatory response | T cell mediated immunity | negative regulation of calcium ion transport | cell activation involved in immune response | sensory perception of sound | adhesion of symbiont to host cell | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | response to monosaccharide | regulation of protein phosphorylation | establishment of endothelial intestinal barrier | regulation of locomotion | regulation of RNA metabolic process | regulation of tube size | viral process | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | lymphocyte activation | positive regulation of molecular function | acute inflammatory response to antigenic stimulus | development of primary male sexual characteristics | positive regulation of protein modification process | response to organic substance | male sex differentiation | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | Sertoli cell development | anatomical structure development | regulation of vasoconstriction | leukocyte cell-cell adhesion | positive regulation of supramolecular fiber organization | regulation of RNA biosynthetic process | negative regulation of programmed cell death | male gonad development | regulation of tube diameter | cellular response to carbohydrate stimulus | chemical homeostasis | cell adhesion | regulation of ruffle assembly | immune response | positive regulation of cellular component biogenesis | animal organ development | positive regulation of NF-kappaB transcription factor activity | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | cell-cell adhesion | cell activation | positive regulation of MAPK cascade | regulation of reactive oxygen species biosynthetic process | sensory perception | establishment of Sertoli cell barrier | regulation of cell communication | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | cellular response to leukemia inhibitory factor | regulation of transcription, DNA-templated | cell development | positive regulation of phosphorylation | reproductive structure development | regulation of developmental process | regulation of ion transport | developmental process | regulation of calcium ion transport | cellular extravasation | regulation of transport | regulation of reactive oxygen species metabolic process | regulation of cell-cell adhesion | positive regulation of protein polymerization | epithelial cell differentiation | T cell migration | positive regulation of nitric oxide biosynthetic process | positive regulation of metabolic process | regulation of actin filament-based process | regulation of cell projection organization | acute inflammatory response | immune system process | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cell motility | response to carbohydrate | negative regulation of cell death | carbohydrate homeostasis | positive regulation of leukocyte cell-cell adhesion | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of signaling | regulation of signaling | negative regulation of endothelial cell apoptotic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | immunological synapse | cell | intrinsic component of membrane | external side of plasma membrane | membrane microdomain | plasma membrane | membrane raft | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cell surface | membrane | intrinsic component of plasma membrane
