QuickView for CDN1;jsessionid=1B324E7953A5D8B2CFC3436D77D2FCE9;jsessionid=48A2B8BBFC172AE9D57529246668979C (gene)
- Gene Symbol:
- Bak1
Rattus norvegicus - Full name:
- BCL2-antagonist/killer 1
- Synonyms:
- Bak, bcl-2 homologous antagonist/killer
- Genomic Location:
- Chr 20: 5255954-5264593
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
ion channel binding | chaperone binding | protein domain specific binding | identical protein binding | protein heterodimerization activity | protein binding | protein homodimerization activity | protein dimerization activity | BH domain binding | heat shock protein binding
GO Biological Process
positive regulation of endoplasmic reticulum unfolded protein response | leukocyte homeostasis | negative regulation of phosphorylation | brain development | limb development | response to radiation | regulation of cysteine-type endopeptidase activity | response to endoplasmic reticulum stress | release of cytochrome c from mitochondria | positive regulation of cellular component organization | regulation of endoplasmic reticulum unfolded protein response | developmental process involved in reproduction | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | proteolysis | regulation of localization | organelle fusion | regulation of programmed cell death | eye development | establishment of localization | fibroblast apoptotic process | negative regulation of cellular process | membrane fusion | protein processing | cell differentiation | nervous system development | intrinsic apoptotic signaling pathway in response to DNA damage | response to drug | negative regulation of protein phosphorylation | cellular chemical homeostasis | post-embryonic animal organ morphogenesis | regulation of organelle organization | membrane organization | B cell differentiation | response to antibiotic | blood vessel morphogenesis | cellular process | lymphocyte differentiation | localization | cellular homeostasis | extrinsic apoptotic signaling pathway | limb morphogenesis | zymogen activation | mitochondrial fusion | tissue remodeling | regulation of mitochondrial membrane potential | negative regulation of peptidyl-serine phosphorylation | reproductive system development | immune system development | establishment or maintenance of transmembrane electrochemical gradient | positive regulation of release of cytochrome c from mitochondria | regulation of proteolysis | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | regulation of binding | intrinsic apoptotic signaling pathway | B cell negative selection | regeneration | response to hydrogen peroxide | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | endocrine pancreas development | cellular component organization | calcium ion homeostasis | response to UV | head development | response to stimulus | vasculature development | cellular response to mechanical stimulus | blood vessel remodeling | positive regulation of protein metabolic process | positive regulation of peptidase activity | cellular response to light stimulus | response to stress | regulation of response to endoplasmic reticulum stress | post-embryonic camera-type eye development | regulation of cell proliferation | tube morphogenesis | positive regulation of cysteine-type endopeptidase activity | regulation of protein homodimerization activity | programmed cell death | reproduction | response to alcohol | cardiovascular system development | positive regulation of proteolysis | apoptotic mitochondrial changes | negative regulation of metabolic process | hemopoiesis | mitochondrion organization | response to mycotoxin | metal ion homeostasis | positive regulation of mitochondrion organization | blood vessel development | myeloid cell homeostasis | response to ethanol | regulation of membrane potential | leukocyte differentiation | regulation of cellular response to stress | apoptotic process | regulation of calcium ion transport into cytosol | response to light stimulus | response to external biotic stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | post-embryonic animal organ development | negative regulation of phosphate metabolic process | multicellular organism development | regulation of peptidase activity | cellular response to DNA damage stimulus | B cell apoptotic process | regulation of catalytic activity | vagina development | regulation of phosphorylation | ion transmembrane transport | post-embryonic camera-type eye morphogenesis | negative regulation of endoplasmic reticulum calcium ion concentration | regulation of gene expression | pancreas development | regulation of mitochondrial membrane permeability | cellular response to stress | positive regulation of cellular metabolic process | cellular ion homeostasis | cellular response to radiation | animal organ morphogenesis | mitochondrial transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | post-embryonic animal morphogenesis | response to oxidative stress | B cell homeostasis | positive regulation of hydrolase activity | homeostasis of number of cells | T cell apoptotic process | B cell activation | cell proliferation | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | protein maturation | response to toxic substance | regulation of apoptotic signaling pathway | endocrine system development | response to gamma radiation | post-embryonic development | cation homeostasis | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | cellular response to UV | sensory organ development | regulation of mitochondrion organization | mitochondrial membrane organization | response to fungus | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | eye morphogenesis | female genitalia development | lymphocyte homeostasis | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | apoptotic process involved in development | homeostatic process | regulation of protein phosphorylation | post-embryonic eye morphogenesis | positive regulation of transport | genitalia development | apoptotic signaling pathway | lymphocyte activation | positive regulation of molecular function | protein metabolic process | response to organic substance | response to mechanical stimulus | anatomical structure development | regulation of protein heterodimerization activity | cell surface receptor signaling pathway | metabolic process | activation of cysteine-type endopeptidase activity involved in apoptotic process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | chemical homeostasis | positive regulation of cell death | organic substance metabolic process | cell death | negative regulation of gene expression | animal organ development | positive regulation of ion transport | response to reactive oxygen species | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | ion homeostasis | regulation of phosphate metabolic process | cell activation | camera-type eye development | regulation of peptidyl-serine phosphorylation | negative regulation of protein metabolic process | regulation of cell communication | regulation of membrane permeability | transmembrane transport | signaling | regulation of protein binding | response to organic cyclic compound | response to UV-C | extrinsic apoptotic signaling pathway in absence of ligand | anatomical structure morphogenesis | regulation of endopeptidase activity | camera-type eye morphogenesis | positive regulation of calcium ion transport into cytosol | response to biotic stimulus | reproductive structure development | regulation of ion transport | endoplasmic reticulum calcium ion homeostasis | developmental process | organelle organization | regulation of calcium ion transport | tube development | regulation of transport | negative regulation of cell proliferation | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | cellular metal ion homeostasis | central nervous system development | positive regulation of metabolic process | apoptotic process involved in morphogenesis | ion transport | thymocyte apoptotic process | immune system process | hematopoietic or lymphoid organ development | female sex differentiation | regulation of cell death | sex differentiation | circulatory system development | aging | divalent inorganic cation homeostasis | activation of cysteine-type endopeptidase activity | regulation of cellular component organization | positive regulation of calcium ion transport | response to ionizing radiation | positive regulation of apoptotic signaling pathway | response to other organism | positive regulation of signaling | apoptotic process involved in blood vessel morphogenesis | signal transduction | regulation of signaling | animal organ regeneration | macromolecule metabolic process | positive regulation of response to endoplasmic reticulum stress | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of organelle membrane | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | mitochondrion | intrinsic component of mitochondrial outer membrane | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | pore complex | BAK complex | outer membrane | integral component of mitochondrial membrane | mitochondrial membrane | cytosol | Bcl-2 family protein complex | intracellular | integral component of mitochondrial outer membrane | membrane
