QuickView for CHRNA4;jsessionid=6B124289245B90F6B51019B167C02182;jsessionid=BBAEE9D1F6A9F89793D093A0A416FFDC (gene)
- Gene Symbol:
- Chrna4
Rattus norvegicus - Full name:
- cholinergic receptor nicotinic alpha 4 subunit
- Synonyms:
- NARAC, neuronal acetylcholine receptor subunit alpha-4, Neuronal nicotinic acetylcholine receptor alpha 4 subunit, cholinergic receptor, nicotinic, alpha 4 (neuronal), cholinergic receptor, nicotinic, alpha polypeptide 4
- Genomic Location:
- Chr 3: 170171214-170186016
- Description:
-
nicotinic acetylcholine receptor subunit responsible for binding calcium sensor protein visinin-like protein-1 (Vilip1), which modulates acetylcholine receptor expression and sensitivity
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
transmitter-gated ion channel activity | acetylcholine-gated cation-selective channel activity | neurotransmitter receptor activity | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | cation transmembrane transporter activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | protein heterodimerization activity | extracellular ligand-gated ion channel activity | ion binding | acetylcholine binding | hormone binding | protein binding | protein dimerization activity | excitatory extracellular ligand-gated ion channel activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | drug binding | ion channel activity | substrate-specific channel activity
GO Biological Process
transmitter-gated ion channel activity | respiratory gaseous exchange | acetylcholine-gated cation-selective channel activity | regulation of localization | establishment of localization | response to hormone | excitatory postsynaptic potential | response to drug | cellular process | regulation of catecholamine secretion | localization | exploration behavior | passive transmembrane transporter activity | acetylcholine receptor signaling pathway | metal ion transport | chemical synaptic transmission | response to hypoxia | regulation of neurological system process | regulation of cellular process | leukocyte activation | regulation of postsynaptic neurotransmitter receptor activity | transmembrane transporter activity | organic cyclic compound metabolic process | ligand-gated ion channel activity | cellular aromatic compound metabolic process | cellular component organization | behavioral response to nicotine | response to stimulus | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | response to stress | regulation of response to drug | regulation of neurotransmitter receptor activity | divalent metal ion transport | cellular nitrogen compound metabolic process | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | DNA repair | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | response to nitrogen compound | cellular response to hormone stimulus | response to nicotine | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | modulation of excitatory postsynaptic potential | cellular response to DNA damage stimulus | protein complex oligomerization | positive regulation of catecholamine secretion | ion transmembrane transport | cellular response to ammonium ion | regulation of postsynaptic membrane potential | positive regulation of secretion | cellular response to stress | nervous system process | synaptic signaling | cation transmembrane transporter activity | response to ammonium ion | response to acetylcholine | response to oxidative stress | ion transmembrane transporter activity | cognition | B cell activation | locomotory behavior | sensory perception of pain | extracellular ligand-gated ion channel activity | response to toxic substance | cellular response to drug | cell communication | positive regulation of response to drug | neuromuscular synaptic transmission | positive regulation of transport | regulation of dopamine secretion | lymphocyte activation | cation transmembrane transport | regulation of signaling receptor activity | protein-containing complex assembly | inhibitory postsynaptic potential | response to organic substance | DNA metabolic process | cell surface receptor signaling pathway | regulation of acetylcholine-gated cation channel activity | metabolic process | calcium ion transport | regulation of secretion | behavior | membrane depolarization | nucleobase-containing compound metabolic process | organic substance metabolic process | positive regulation of ion transport | excitatory extracellular ligand-gated ion channel activity | regulation of ion transmembrane transport | cell activation | cation channel activity | adult behavior | sensory perception | regulation of cell communication | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | positive regulation of dopamine secretion | protein heterooligomerization | cation transport | channel activity | regulation of ion transport | regulation of transport | synaptic transmission, cholinergic | regulation of cation channel activity | heterocycle metabolic process | ion channel activity | ion transport | immune system process | cellular metabolic process | cellular response to organic substance | substrate-specific channel activity | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | external side of plasma membrane | receptor complex | dendritic tree | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | integral component of plasma membrane | cell periphery | transmembrane transporter complex | ion channel complex | cell surface | cell junction | acetylcholine-gated channel complex | membrane | intrinsic component of plasma membrane
