QuickView for CPA7;jsessionid=C0E875239F36EBA654D3097CFEF6FD12;jsessionid=A11B40F81A8D66FEF3910A69A1976AF8 (gene)
- Gene Symbol:
- Cyp2a3
Rattus norvegicus - Full name:
- cytochrome P450, family 2, subfamily a, polypeptide 3
- Synonyms:
- Cyp2a3a, RATCYP2A3A, cytochrome P450 2A3, CYPIIA3, coumarin 7-hydroxylase, cytochrome P450, family 2, subfamily A, polypeptide 3a, cytochrome P450, subfamily IIA (phenobarbital-inducble)/ (cytochrome P450 IIA3)
- Genomic Location:
- Chr 1: 81944896-81952812
- Description:
-
activates carcinogen N-nitrosomethylbenzylamine (NMBA) metabolism in the esophagus
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | drug binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity | small molecule binding | arachidonic acid epoxygenase activity
GO Biological Process
response to metal ion | response to drug | cellular process | response to inorganic substance | heme metabolic process | porphyrin-containing compound metabolic process | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular response to metal ion | response to stilbenoid | response to stimulus | cellular response to xenobiotic stimulus | cellular response to inorganic substance | cellular response to cadmium ion | cofactor metabolic process | drug catabolic process | nitrogen compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | small molecule metabolic process | exogenous drug catabolic process | response to cadmium ion | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | drug metabolic process | response to organic substance | metabolic process | oxidation-reduction process | organic substance metabolic process | pigment metabolic process | coumarin metabolic process | response to organic cyclic compound | organic acid metabolic process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | aromatase activity | arachidonic acid epoxygenase activity
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
