QuickView for CRDGF;jsessionid=76707BEF1A335A7C4FFEBE7A666DEA81;jsessionid=F1F8D670C17F5A9706463C48444A8FEB (gene)

Gene Symbol:

Areg Mus musculus

Full name:

amphiregulin

Synonyms:

AR, Mcub, Sdgf, amphiregulin, schwannoma-derived growth factor

Genomic Location:

Chr 5: 91568641-91577458

Description:

This gene encodes a member of the epidermal growth factor (EGF) family and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland develop...

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This gene encodes a member of the epidermal growth factor (EGF) family and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CREB_01 ,  CREBP1CJUN_01 ,  ATF_B ,  ATF3_Q6 ,  ATF1_Q6 ,  CREB_Q2_01 ,  CREB_Q4_01 ,  TGACGTCA_ATF3_Q6 ,  TGAYRTCA_ATF3_Q6 ,  TGGAAA_NFAT_Q4_01 ,  TATAAA_TATA_01

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