QuickView for CRH;jsessionid=FC53D48664FD9BE7F519DA25783A5601;jsessionid=8DF24212A3C5D967C91265DA13384995 (gene)
- Gene Symbol:
- Crh
Rattus norvegicus - Full name:
- corticotropin releasing hormone
- Synonyms:
- CRF, corticoliberin, corticotropin-releasing factor
- Genomic Location:
- Chr 2: 104764023-104765887
- Description:
-
binds CRH receptors and mediates neuroendocrine stress response; may play a role in the consolidation of long term memory
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AAAYRNCTG_UNKNOWN , AACTTT_UNKNOWN , CREB_01 , CREBP1CJUN_01 , EVI1_04 , CDPCR3_01 , CREB_02 , HFH1_01 , FOXD3_01 , SRY_02
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
hormone receptor binding | signaling receptor binding | corticotropin-releasing hormone activity | hormone activity | neuropeptide receptor binding | molecular function regulator | corticotropin-releasing hormone receptor 2 binding | peptide hormone receptor binding | protein binding | receptor regulator activity | corticotropin-releasing hormone receptor binding | G-protein coupled receptor binding | receptor ligand activity | corticotropin-releasing hormone receptor 1 binding
GO Biological Process
brain development | positive regulation of insulin secretion involved in cellular response to glucose stimulus | regulation of corticosterone secretion | positive regulation of behavior | regulation of cellular localization | negative regulation of peptide secretion | regulation of localization | response to immobilization stress | response to hormone | negative regulation of cellular process | response to dexamethasone | respiratory tube development | defense response | nervous system development | response to drug | positive regulation of phosphate metabolic process | regulation of peptide hormone secretion | positive regulation of protein secretion | response to antibiotic | regulation of lipid transport | hormone-mediated signaling pathway | cellular process | negative regulation of glucagon secretion | regulation of catecholamine secretion | exploration behavior | positive regulation of synaptic transmission | negative regulation of signaling | chemical synaptic transmission | female pregnancy | regulation of digestive system process | learning | negative regulation of secretion | response to corticosterone | positive regulation of nitrogen compound metabolic process | diencephalon development | regulation of fear response | negative regulation of hormone secretion | regulation of behavior | negative regulation of gonadotropin secretion | regulation of cellular process | cellular response to lipid | regulation of metabolic process | response to ether | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | steroid biosynthetic process | cellular lipid metabolic process | head development | regulation of peptide secretion | associative learning | response to stimulus | respiratory system development | response to pain | regulation of insulin secretion | positive regulation of protein metabolic process | regulation of norepinephrine secretion | response to cocaine | cellular response to xenobiotic stimulus | response to stress | hypothalamus development | regulation of response to drug | regulation of cell proliferation | positive regulation of behavioral fear response | programmed cell death | regulation of neurotransmitter receptor activity | reproduction | response to alcohol | corticotropin-releasing hormone activity | positive regulation of hormone secretion | negative regulation of transport | cellular response to organic cyclic compound | hormone activity | regulation of protein transport | blood circulation | negative regulation of metabolic process | regulation of peptide transport | modulation of chemical synaptic transmission | cell-cell signaling | synaptic transmission, dopaminergic | positive regulation of corticotropin secretion | molecular function regulator | negative regulation of blood pressure | response to ethanol | positive regulation of peptide secretion | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | negative regulation of epinephrine secretion | reproductive process | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | hormone biosynthetic process | learning or memory | regulation of insulin secretion involved in cellular response to glucose stimulus | lipid metabolic process | hormone-mediated apoptotic signaling pathway | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of calcium ion import | cellular response to ammonium ion | regulation of gene expression | positive regulation of secretion | response to ketone | response to lipid | nervous system process | regulation of behavioral fear response | regulation of blood pressure | synaptic signaling | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | response to ammonium ion | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | response to corticosteroid | cellular response to alkaloid | positive regulation of digestive system process | negative regulation of norepinephrine secretion | cognition | positive regulation of corticosterone secretion | biosynthetic process | locomotory behavior | regulation of cellular protein metabolic process | negative regulation of peptide hormone secretion | cellular response to glucocorticoid stimulus | lipid biosynthetic process | response to toxic substance | positive regulation of lipid localization | regulation of serotonin secretion | response to xenobiotic stimulus | endocrine system development | cellular response to corticosteroid stimulus | cellular response to drug | response to estrogen | cell communication | regulation of cellular metabolic process | positive regulation of response to drug | inflammatory response | regulation of endocrine process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of cAMP-mediated signaling | homeostatic process | limbic system development | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | positive regulation of transport | positive regulation of peptide hormone secretion | apoptotic signaling pathway | negative regulation of catecholamine secretion | regulation of signaling receptor activity | receptor regulator activity | multicellular organismal response to stress | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | gland development | positive regulation of insulin secretion | response to antineoplastic agent | regulation of intracellular signal transduction | anatomical structure development | negative regulation of luteinizing hormone secretion | metabolic process | response to mineralocorticoid | adrenal gland development | chemical homeostasis | regulation of secretion | behavior | positive regulation of cell death | receptor ligand activity | organic substance metabolic process | cell death | negative regulation of gene expression | animal organ development | positive regulation of ion transport | forebrain development | regulation of protein secretion | diterpenoid metabolic process | positive regulation of cAMP-mediated signaling | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | cellular response to steroid hormone stimulus | regulation of ion transmembrane transport | lung development | cellular response to dexamethasone stimulus | cellular response to cocaine | positive regulation of protein transport | steroid metabolic process | regulation of calcium ion import | regulation of cell communication | regulation of corticotropin secretion | signaling | glucocorticoid metabolic process | response to organic cyclic compound | negative regulation of systemic arterial blood pressure | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | hormone metabolic process | regulation of glucagon secretion | regulation of NMDA receptor activity | isoprenoid metabolic process | regulation of ion transport | developmental process | regulation of calcium ion transport | glucocorticoid biosynthetic process | tube development | regulation of transport | regulation of cation channel activity | response to organonitrogen compound | locomotory exploration behavior | regulation of glutamate receptor signaling pathway | central nervous system development | response to anesthetic | positive regulation of metabolic process | regulation of synaptic plasticity | positive regulation of lipid transport | cellular metabolic process | long-term synaptic potentiation | cellular response to organic substance | regulation of protein localization | regulation of cell death | response to steroid hormone | negative regulation of cell death | positive regulation of cortisol secretion | positive regulation of calcium ion transport | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
neuron projection | somatodendritic compartment | cell body | cell | varicosity | neuronal cell body | cytoplasm | main axon | cell projection | perikaryon | extracellular region | extracellular space | axon | intracellular
