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QuickView for CRLF2;jsessionid=21A3AB0C769A7365AA988C48CFCBFEC0;jsessionid=FA81342DDDC21FFC2910DB436D4D96B0 (gene)


Gene Symbol:
Crlf2 Rattus norvegicus Rattus norvegicus
Full name:
cytokine receptor-like factor 2
Synonyms:
Crl2, Tpte2, Tslpr, cytokine receptor-like factor 2, TSLP receptor, thymic stromal lymphopoietin protein receptor, thymic stromal-derived lymphopoietin, receptor, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
Genomic Location:
N/A
Description:
contains conserved WSXWS motif found in all cytokine receptors; binds to the cytokine thymic stromal derived lymphopoietin (TSLP)
Orthologs:
Homo sapiens Mus musculus Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene


Transcripts Names
NM_134465
XM_008769915
XM_008769916
Protein Names
Q6AZ53



GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | interleukin-2 binding | signaling receptor binding | growth factor binding | molecular function regulator | signaling receptor activity | protein heterodimerization activity | cytokine receptor activity | protein binding | receptor regulator activity | protein dimerization activity | receptor ligand activity | cytokine activity

GO Biological Process

adaptive immune response | response to cytokine | regulation of localization | establishment of localization | regulation of immune system process | defense response | positive regulation of protein secretion | cellular process | secretion | localization | protein transport | macromolecule localization | regulation of cellular process | immunoglobulin secretion | type 2 immune response | T cell cytokine production | regulation of peptide secretion | response to stimulus | positive regulation of interleukin-5 secretion | positive regulation of immune system process | response to stress | regulation of cell proliferation | positive regulation of cell activation | secretion by cell | positive regulation of cytokine secretion | regulation of protein transport | regulation of peptide transport | molecular function regulator | positive regulation of peptide secretion | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | regulation of signal transduction | leukocyte mediated immunity | positive regulation of secretion | organic substance transport | CD4-positive, alpha-beta T cell cytokine production | regulation of mast cell activation | positive regulation of STAT cascade | peptide transport | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | cellular response to cytokine stimulus | cytokine production involved in immune response | cytokine receptor activity | peptide secretion | cell communication | inflammatory response | T cell mediated immunity | positive regulation of signal transduction | positive regulation of cell proliferation | positive regulation of establishment of protein localization | T-helper 2 cell cytokine production | positive regulation of transport | regulation of cytokine secretion | cytokine production | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | response to organic substance | regulation of intracellular signal transduction | cell surface receptor signaling pathway | immunoglobulin production involved in immunoglobulin mediated immune response | immunoglobulin production | positive regulation of leukocyte activation | regulation of interleukin-5 production | amide transport | regulation of secretion | receptor ligand activity | immune response | cytokine activity | positive regulation of mast cell activation | regulation of cell activation | regulation of protein secretion | positive regulation of interleukin-5 production | establishment of protein localization | positive regulation of cytokine production | positive regulation of protein transport | regulation of cell communication | signaling | protein localization | regulation of cytokine production | B cell mediated immunity | regulation of transport | immunoglobulin secretion involved in immune response | immunoglobulin mediated immune response | immune system process | cellular response to organic substance | regulation of protein localization | protein secretion | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | receptor complex | protein-containing complex | plasma membrane | cell periphery | cell surface | membrane