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QuickView for CTNNB1;jsessionid=3CA831FEA6DBEDA7EE44CC58C4043ACE;jsessionid=A7F26CC2441C12438F50C091D03A5604 (gene)


Gene Symbol:
Ctnnb1 Rattus norvegicus Rattus norvegicus
Full name:
catenin beta 1
Synonyms:
Catnb, catenin beta-1, beta-catenin, catenin (cadherin associated protein), beta 1, 88kDa
Genomic Location:
Chr 8: 125978161-125987670
Description:
involved in mediating the interaction between cadherins and the actin cytoskeleton
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

kinase binding | cadherin binding | repressing transcription factor binding | hormone receptor binding | protein kinase binding | enzyme binding | RNA polymerase II activating transcription factor binding | protein-containing complex binding | disordered domain specific binding | estrogen receptor binding | signaling receptor binding | chromatin binding | ion channel binding | protein domain specific binding | nuclear hormone receptor binding | protein heterodimerization activity | cell adhesion molecule binding | transcription coactivator activity | I-SMAD binding | protein binding | DNA-binding transcription factor activity | protein phosphatase binding | transcription factor binding | alpha-catenin binding | RNA polymerase II transcription factor binding | activating transcription factor binding | protein dimerization activity | nitric-oxide synthase binding | steroid hormone receptor binding | phosphatase binding | transcription coregulator activity | SMAD binding | protein C-terminus binding | glutamate receptor binding | ionotropic glutamate receptor binding

GO Biological Process

RNA metabolic process | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | regulation of telomere maintenance via telomerase | brain development | limb development | regulation of epithelial cell differentiation involved in kidney development | molting cycle | cell morphogenesis | glial cell proliferation | sympathetic ganglion development | lung induction | regulation of cell cycle process | nephron tubule formation | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | negative regulation of embryonic development | epidermis morphogenesis | response to cytokine | regulation of cellular response to oxidative stress | positive regulation of cellular component organization | regulation of response to oxidative stress | cell motility | regulation of neurogenesis | ectodermal placode formation | neuron projection morphogenesis | cranial skeletal system development | developmental process involved in reproduction | dorsal root ganglion development | regulation of cellular localization | positive regulation of skeletal muscle tissue development | endothelial cell development | positive regulation of apoptotic process | regulation of cell development | regulation of localization | cell-substrate adhesion | regulation of epithelial cell proliferation involved in prostate gland development | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | positive regulation of striated muscle tissue development | regulation of euchromatin binding | positive regulation of embryonic development | regulation of programmed cell death | negative regulation of cellular response to oxidative stress | foregut morphogenesis | embryonic brain development | cellular response to indole-3-methanol | eye development | smooth muscle cell differentiation | embryonic skeletal joint morphogenesis | establishment of localization | regulation of immune system process | response to hormone | myeloid cell differentiation | negative regulation of neuron death | neuron migration | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | embryonic appendage morphogenesis | response to metal ion | negative regulation of mitotic cell cycle, embryonic | microtubule cytoskeleton organization | cell differentiation | positive regulation of epithelial cell proliferation | endothelial cell differentiation | respiratory tube development | adherens junction assembly | nervous system development | response to drug | canonical Wnt signaling pathway involved in regulation of cell proliferation | hair follicle placode formation | cell part morphogenesis | oviduct development | neurogenesis | bone remodeling | negative regulation of osteoclast differentiation | positive regulation of phosphate metabolic process | regulation of organelle organization | generation of neurons | mesenchyme development | tissue homeostasis | intracellular transport | regulation of neuroblast proliferation | microtubule-based process | blood vessel morphogenesis | pattern specification process | regulation of neuron death | neuron projection extension | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | regulation of gene expression, epigenetic | positive regulation of glycoprotein biosynthetic process | negative regulation of gliogenesis | cell fate specification | establishment of blood-brain barrier | negative regulation of oxidative stress-induced neuron death | lymphocyte differentiation | establishment of organelle localization | localization | cell projection morphogenesis | epithelial tube morphogenesis | chromatin organization | limb morphogenesis | cell maturation | odontogenesis | tissue remodeling | forebrain cell migration | negative regulation of signaling | developmental growth | chemical synaptic transmission | neuron development | central nervous system neuron differentiation | reproductive system development | canonical Wnt signaling pathway | response to estradiol | positive regulation of epithelial to mesenchymal transition | regulation of embryonic development | immune system development | positive regulation of telomerase activity | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | renal tubule morphogenesis | regulation of striated muscle tissue development | renal outer medulla development | macromolecule localization | negative regulation of apoptotic process | branching involved in ureteric bud morphogenesis | digestive tract morphogenesis | dorsal/ventral axis specification | microtubule organizing center organization | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | response to inorganic substance | establishment of localization in cell | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of binding | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | gamete generation | positive regulation of endothelial cell differentiation | muscle structure development | anatomical structure homeostasis | muscle cell differentiation | cell junction assembly | autonomic nervous system development | hindlimb morphogenesis | negative regulation of apoptotic signaling pathway | regulation of angiogenesis | regulation of cellular process | positive regulation of chromatin-mediated maintenance of transcription | leukocyte activation | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | gliogenesis | regulation of protein complex assembly | organelle localization | hepaticobiliary system development | regulation of nephron tubule epithelial cell differentiation | organic cyclic compound metabolic process | fungiform papilla morphogenesis | positive regulation of cellular protein metabolic process | bone resorption | RNA biosynthetic process | negative regulation of oxidative stress-induced cell death | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | cellular component organization | epithelial tube branching involved in lung morphogenesis | canonical Wnt signaling pathway involved in negative regulation of apoptotic process | cellular response to metal ion | urogenital system development | T cell activation | nephron tubule morphogenesis | head development | cranial nerve development | branching involved in blood vessel morphogenesis | regulation of vasculature development | response to stimulus | cellular response to lithium ion | thymus development | positive regulation of heparan sulfate proteoglycan biosynthetic process | vasculature development | regulation of centriole-centriole cohesion | female gamete generation | regulation of glycoprotein biosynthetic process | regulation of cellular protein localization | cellular response to mechanical stimulus | embryonic limb morphogenesis | midgut development | respiratory system development | cellular response to fibroblast growth factor stimulus | regulation of centrosome cycle | embryonic epithelial tube formation | cerebral cortex radial glia guided migration | positive regulation of protein metabolic process | renal vesicle formation | regulation of cardioblast proliferation | establishment of endothelial blood-brain barrier | germ cell development | ganglion development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | multicellular organismal homeostasis | positive regulation of neuroblast proliferation | negative regulation of angiogenesis | tube morphogenesis | response to peptide | epithelial cell development | renal inner medulla development | telencephalon cell migration | regulation of epithelial cell differentiation | regulation of transcription regulatory region DNA binding | epithelial tube formation | reproduction | cellular response to inorganic substance | cellular localization | central nervous system vasculogenesis | embryonic skeletal system development | response to alcohol | cardiovascular system development | midbrain development | cellular nitrogen compound metabolic process | endodermal cell fate commitment | regulation of DNA binding | cellular response to organic cyclic compound | metanephros morphogenesis | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | negative regulation of hemopoiesis | cellular biosynthetic process | dorsal/ventral pattern formation | kidney development | embryo development | regulation of morphogenesis of a branching structure | cell-cell signaling | regulation of chromatin binding | regulation of oligodendrocyte differentiation | trachea morphogenesis | positive regulation of telomere maintenance via telomere lengthening | cell surface receptor signaling pathway involved in cell-cell signaling | blood vessel development | anterior/posterior pattern specification | tongue development | regulation of nucleic acid-templated transcription | leukocyte differentiation | regulation of cellular response to stress | locomotion | response to nitrogen compound | embryonic skeletal joint development | cellular response to hormone stimulus | regulation of skeletal muscle tissue development | system development | canonical Wnt signaling pathway involved in heart development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | endothelium development | ureteric bud development | Wnt signaling pathway | adherens junction organization | regulation of cartilage development | multicellular organism development | response to activity | cell migration | cellular response to peptide hormone stimulus | regulation of MAPK cascade | epithelial cell differentiation involved in prostate gland development | protein complex oligomerization | regulation of telomere maintenance | positive regulation of muscle organ development | regulation of catalytic activity | regulation of protein localization to cell surface | oocyte differentiation | regulation of phosphorylation | kidney morphogenesis | regulation of ossification | regulation of mitotic cell cycle, embryonic | hair follicle morphogenesis | positive regulation of chromosome organization | regulation of T cell activation | telencephalon development | regulation of gene expression | forelimb morphogenesis | osteoclast differentiation | kidney epithelium development | pancreas development | fungiform papilla development | response to lipid | cellular response to peptide | cell cycle | synaptic signaling | embryonic axis specification | regulation of epidermis development | myeloid leukocyte differentiation | regulation of stem cell proliferation | regulation of fibroblast growth factor receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | chromatin-mediated maintenance of transcription | ectodermal placode development | regulation of telomerase activity | regulation of lymphocyte activation | animal organ morphogenesis | liver development | establishment of endothelial barrier | negative regulation of myeloid cell differentiation | canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation | negative regulation of chondrocyte differentiation | regulation of myelination | regulation of nitrogen compound metabolic process | embryonic forelimb morphogenesis | glial cell migration | apical junction assembly | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | regulation of hair follicle development | vesicle-mediated transport | regulation of branching involved in lung morphogenesis | regulation of transcription by RNA polymerase II | endoderm formation | oogenesis | response to lithium ion | positive regulation of gene expression, epigenetic | synapse organization | bicellular tight junction assembly | positive regulation of cell differentiation | renal vesicle morphogenesis | regulation of cell proliferation involved in heart morphogenesis | establishment of vesicle localization | cell proliferation | biosynthetic process | response to cadmium ion | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | glial cell differentiation | positive regulation of ossification | angiogenesis | hindbrain development | regulation of centromeric sister chromatid cohesion | positive regulation of epithelial cell proliferation involved in prostate gland development | mesonephric epithelium development | digestive tract development | positive regulation of neuron death | epidermis development | positive regulation of telomere maintenance via telomerase | regulation of apoptotic signaling pathway | skin development | cerebral cortex cell migration | protein localization to cell surface | cell morphogenesis involved in differentiation | regulation of protein sumoylation | positive regulation of fibroblast growth factor receptor signaling pathway | mesonephros development | sensory organ development | trachea formation | gastrulation with mouth forming second | cellular response to drug | proximal/distal pattern formation | regulation of telomere maintenance via telomere lengthening | response to estrogen | chordate embryonic development | animal organ formation | regulation of timing of anagen | cell communication | regulation of cellular metabolic process | chromatin remodeling | eye morphogenesis | regulation of core promoter binding | sympathetic nervous system development | regulation of neuron apoptotic process | skeletal system morphogenesis | metanephros development | anterior/posterior axis specification | renal tubule development | positive regulation of DNA biosynthetic process | odontogenesis of dentin-containing tooth | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | heart development | glial cell fate determination | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | transcription coactivator activity | regulation of RNA metabolic process | renal system development | genitalia development | cerebral cortex development | cranial ganglion development | regulation of cellular response to growth factor stimulus | canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | embryonic hindlimb morphogenesis | embryonic morphogenesis | regulation of mitotic cell cycle | regulation of microtubule-based process | negative regulation of epithelial cell differentiation | nephron development | lymphocyte activation | positive regulation of molecular function | positive regulation of osteoblast differentiation | regulation of sister chromatid cohesion | neuron differentiation | multicellular organism reproduction | embryonic organ morphogenesis | T cell differentiation | protein-containing complex assembly | ureteric bud morphogenesis | DNA-binding transcription factor activity | cellular response to insulin-like growth factor stimulus | regionalization | axis specification | positive regulation of protein modification process | hair cycle | response to organic substance | gland development | T cell differentiation in thymus | lens morphogenesis in camera-type eye | tissue morphogenesis | digestive system development | regulation of hemopoiesis | centrosome cycle | branching morphogenesis of an epithelial tube | male sex differentiation | response to antineoplastic agent | response to mechanical stimulus | regulation of animal organ morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | regulation of sister chromatid segregation | positive regulation of neuron apoptotic process | negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | embryonic heart tube development | anatomical structure development | developmental growth involved in morphogenesis | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | embryonic skeletal system morphogenesis | endothelial tube morphogenesis | cell projection organization | metabolic process | positive regulation of cell development | regulation of chromatin-mediated maintenance of transcription | negative regulation of response to oxidative stress | cell fate commitment | positive regulation of DNA-templated transcription, initiation | cell-cell junction assembly | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | embryonic organ development | negative regulation of mitotic cell cycle | cellular protein localization | hair cycle process | positive regulation of cell death | cell adhesion | trachea development | morphogenesis of embryonic epithelium | positive regulation of determination of dorsal identity | regulation of chondrocyte differentiation | male genitalia development | midbrain dopaminergic neuron differentiation | nucleobase-containing compound metabolic process | neuron projection development | mesenchymal cell proliferation | positive regulation of cellular component biogenesis | organic substance metabolic process | positive regulation of core promoter binding | Schwann cell proliferation | negative regulation of biosynthetic process | negative regulation of gene expression | nephron morphogenesis | animal organ development | cerebral cortex radially oriented cell migration | lung-associated mesenchyme development | forebrain development | nerve development | pallium development | negative regulation of cellular protein metabolic process | gene expression | positive regulation of proteoglycan biosynthetic process | regulation of cell activation | neural plate development | positive regulation of programmed cell death | positive regulation of branching involved in lung morphogenesis | regulation of heart morphogenesis | skin epidermis development | genitalia morphogenesis | regulation of phosphate metabolic process | cytoskeleton organization | regulation of chromosome organization | positive regulation of binding | positive regulation of muscle tissue development | positive regulation of glycoprotein metabolic process | cell-cell adhesion | transcription, DNA-templated | ectoderm development | dopaminergic neuron differentiation | cell activation | positive regulation of MAPK cascade | lung development | oocyte development | morphogenesis of a branching epithelium | camera-type eye development | anatomical structure formation involved in morphogenesis | negative regulation of cartilage development | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of animal organ formation | negative regulation of protein sumoylation | regulation of osteoclast differentiation | regulation of glial cell differentiation | regulation of calcium ion import | regulation of cell communication | regulation of gliogenesis | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | limb joint morphogenesis | regulation of transcription, DNA-templated | cell-matrix adhesion | response to organic cyclic compound | glial cell fate commitment | regulation of secondary heart field cardioblast proliferation | myoblast differentiation | response to indole-3-methanol | cell development | embryonic digit morphogenesis | positive regulation of DNA binding | regulation of T cell proliferation | synaptic vesicle localization | protein localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | endodermal cell differentiation | endoderm development | protein heterooligomerization | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | cellular macromolecule localization | cellular macromolecule biosynthetic process | cell fate commitment involved in formation of primary germ layer | positive regulation of stem cell proliferation | regulation of DNA-templated transcription, initiation | camera-type eye morphogenesis | tongue morphogenesis | reproductive structure development | regulation of nervous system development | regulation of developmental process | regulation of ion transport | positive regulation of telomere maintenance | positive regulation of neural precursor cell proliferation | renal vesicle development | positive regulation of DNA metabolic process | regulation of mesenchymal cell proliferation | developmental process | layer formation in cerebral cortex | organelle organization | regulation of DNA biosynthetic process | lung cell differentiation | regulation of calcium ion transport | negative regulation of glial cell differentiation | positive regulation of epithelial cell differentiation | negative regulation of transcription by RNA polymerase II | tube development | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | mesenchymal cell proliferation involved in lung development | regulation of hair cycle | developmental cell growth | fungiform papilla formation | negative regulation of vasculature development | response to fibroblast growth factor | positive regulation of mesenchymal cell proliferation | regulation of endothelial cell differentiation | positive regulation of nucleic acid-templated transcription | cell fate determination | response to organonitrogen compound | transcription coregulator activity | lung morphogenesis | epithelial cell differentiation | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | regulation of epithelial to mesenchymal transition | heterocycle metabolic process | tube formation | central nervous system development | in utero embryonic development | positive regulation of metabolic process | chromosome organization | vesicle localization | organ induction | skeletal system development | gastrulation | immune system process | embryonic foregut morphogenesis | cellular metabolic process | hematopoietic or lymphoid organ development | synaptic vesicle transport | cellular response to organic substance | regulation of protein localization | regulation of cell death | sex differentiation | regulation of smooth muscle cell proliferation | negative regulation of oligodendrocyte differentiation | negative regulation of cell death | negative regulation of cell development | developmental induction | circulatory system development | sexual reproduction | nephron tubule development | negative regulation of myeloid leukocyte differentiation | regulation of microtubule cytoskeleton organization | regulation of I-kappaB kinase/NF-kappaB signaling | negative regulation of cell differentiation | regulation of cellular component organization | lens development in camera-type eye | regulation of cytoskeleton organization | positive regulation of signaling | hair follicle development | embryonic skeletal limb joint morphogenesis | signal transduction | regulation of signaling | mesonephric tubule development | positive regulation of gene expression | embryonic pattern specification | positive regulation of transcription regulatory region DNA binding | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | cell-cell junction organization | regulation of chromatin organization | regulation of phosphorus metabolic process

GO Cellular Component

nuclear euchromatin | nuclear transcription factor complex | supramolecular fiber | occluding junction | intercalated disc | exocytic vesicle | chromosome | catenin-TCF7L2 complex | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | extrinsic component of membrane | Scrib-APC-beta-catenin complex | catenin complex | somatodendritic compartment | adherens junction | Wnt signalosome | organelle membrane | cell projection membrane | sarcomere | microtubule organizing center | RNA polymerase II transcription factor complex | nuclear membrane | cytoplasmic vesicle | fascia adherens | actin-based cell projection | cell | nuclear lumen | plasma membrane protein complex | extrinsic component of plasma membrane | transcription factor complex | lamellipodium | myofibril | cytoplasm | spindle | intracellular organelle | membrane microdomain | dendritic tree | contractile fiber | apical part of cell | cell-cell adherens junction | centrosome | cell-cell junction | cell-cell contact zone | euchromatin | protein-containing complex | cell projection | secretory vesicle | endomembrane system | protein-DNA complex | plasma membrane | nuclear envelope | chromatin | cell leading edge | nuclear chromosome | membrane raft | vesicle | transport vesicle | perinuclear region of cytoplasm | microtubule cytoskeleton | cytoplasmic region | beta-catenin destruction complex | spindle pole | beta-catenin-TCF7L2 complex | beta-catenin-TCF complex | cell cortex | microvillus | membrane-bounded organelle | dendritic shaft | apical junction complex | nucleus | organelle | I band | flotillin complex | cell periphery | bicellular tight junction | microvillus membrane | membrane-enclosed lumen | basolateral plasma membrane | nuclear chromatin | plasma membrane raft | Z disc | cytosol | intracellular vesicle | cytoskeleton | intracellular | cell junction | caveola | lateral plasma membrane | membrane | supramolecular complex