QuickView for CX3CR1;jsessionid=F22B1524D83792BC5FC5B755AC561D6A;jsessionid=5CA158C7B506EB7AFFC9EF2FC1D16555 (gene)
- Gene Symbol:
- Cx3cr1
Mus musculus - Full name:
- chemokine (C-X3-C motif) receptor 1
- Synonyms:
- CX3C chemokine receptor 1, C-X3-C CKR-1, chemokine (C-X3-C) receptor 1, fractalkine receptor
- Genomic Location:
- Chr 9: 119957811-119977400
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cytokine binding | C-X3-C chemokine receptor activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | chemokine binding | C-X3-C chemokine binding | signaling receptor activity | G-protein coupled chemoattractant receptor activity | cytokine receptor activity | protein binding | C-C chemokine receptor activity | peptide receptor activity | chemokine receptor activity | G-protein coupled peptide receptor activity | C-C chemokine binding
GO Biological Process
brain development | regulation of extrinsic apoptotic signaling pathway in absence of ligand | macrophage chemotaxis | macrophage migration | response to cytokine | cell motility | regulation of neurogenesis | response to lipopolysaccharide | intracellular signal transduction | regulation of cell development | regulation of localization | regulation of programmed cell death | regulation of nitric oxide biosynthetic process | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | chemokine-mediated signaling pathway | defense response | nervous system development | cellular chemical homeostasis | negative regulation of chronic inflammatory response to non-antigenic stimulus | neurogenesis | negative regulation of chronic inflammatory response | generation of neurons | regulation of neuroblast proliferation | cellular process | C-X3-C chemokine receptor activity | negative regulation of inflammatory response | regulation of cytokine biosynthetic process | regulation of cell motility | localization | cellular homeostasis | forebrain cell migration | negative regulation of signaling | negative regulation of apoptotic process | negative regulation of cell migration | regulation of cell differentiation | negative regulation of apoptotic signaling pathway | negative regulation of cell motility | regulation of angiogenesis | regulation of cellular process | leukocyte activation | regulation of apoptotic process | cellular response to lipid | leukocyte tethering or rolling | regulation of metabolic process | regulation of cytosolic calcium ion concentration | cellular response to molecule of bacterial origin | calcium ion homeostasis | head development | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | regulation of long-term synaptic potentiation | response to stress | leukocyte activation involved in immune response | regulation of cell proliferation | positive regulation of neuroblast proliferation | negative regulation of angiogenesis | telencephalon cell migration | response to molecule of bacterial origin | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | microglial cell activation involved in immune response | cell chemotaxis | metal ion homeostasis | leukocyte migration | regulation of neurotransmitter levels | locomotion | response to external biotic stimulus | system development | regulation of signal transduction | multicellular organism development | cell migration | learning or memory | telencephalon development | regulation of extrinsic apoptotic signaling pathway | response to lipid | nervous system process | regulation of stem cell proliferation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | cytokine-mediated signaling pathway | regulation of cellular component movement | G-protein coupled chemoattractant receptor activity | positive regulation of cell differentiation | second-messenger-mediated signaling | negative regulation of extrinsic apoptotic signaling pathway | cognition | macrophage activation involved in immune response | cellular response to cytokine stimulus | regulation of apoptotic signaling pathway | microglial cell activation | cerebral cortex cell migration | regulation of tumor necrosis factor production | cation homeostasis | cytokine receptor activity | response to bacterium | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | leukocyte chemotaxis | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of locomotion | cerebral cortex development | calcium-mediated signaling | response to organic substance | leukocyte adhesion to vascular endothelial cell | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | regulation of chronic inflammatory response | leukocyte cell-cell adhesion | positive regulation of cell development | negative regulation of long-term synaptic potentiation | negative regulation of programmed cell death | chemical homeostasis | behavior | cell adhesion | macrophage activation | immune response | regulation of tumor necrosis factor biosynthetic process | animal organ development | forebrain development | pallium development | negative regulation of cellular component movement | ion homeostasis | phospholipase C-activating G-protein coupled receptor signaling pathway | cell-cell adhesion | cell activation | regulation of reactive oxygen species biosynthetic process | memory | C-C chemokine receptor activity | regulation of cell communication | negative regulation of signal transduction | chemokine receptor activity | signaling | G-protein coupled peptide receptor activity | regulation of cytokine production | positive regulation of stem cell proliferation | response to biotic stimulus | regulation of nervous system development | regulation of developmental process | positive regulation of neural precursor cell proliferation | developmental process | cellular extravasation | regulation of reactive oxygen species metabolic process | innate immune response | negative regulation of vasculature development | cellular metal ion homeostasis | central nervous system development | regulation of synaptic plasticity | immune system process | cellular response to organic substance | regulation of cell death | negative regulation of cell death | regulation of inflammatory response | chemotaxis | divalent inorganic cation homeostasis | negative regulation of locomotion | positive regulation of angiogenesis | response to other organism | signal transduction | regulation of signaling | cellular response to lipopolysaccharide | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell body | cell | nuclear lumen | neuronal cell body | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | cell projection | nucleoplasm | plasma membrane | neuronal cell body membrane | perinuclear region of cytoplasm | membrane-bounded organelle | nucleus | organelle | cell periphery | cell body membrane | membrane-enclosed lumen | cell surface | intracellular | membrane
