QuickView for CXCL2;jsessionid=D96D834B3238718491665385F3A6BF55;jsessionid=B19BA32068BF88A6F403FBD31CDDE43D;jsessionid=A802C6BCE7A7701819B5488A4A469F45;jsessionid=0F761B276403FD5962FD4A17CA79B836 (gene)

Gene Symbol:

CXCL2 Homo sapiens

Full name:

C-X-C motif chemokine ligand 2

Synonyms:

CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2, C-X-C motif chemokine 2, GRO2 oncogene, MGSA beta, MIP2-alpha, chemokine (C-X-C motif) ligand 2, gro-beta, growth-regulated protein beta, macrophage inflammatory protein 2-alpha, melanoma growth stimulatory activity beta

Genomic Location:

Chr 4: 75181616-75183861

Description:

This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites o...

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This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGTG_MIR128A_MIR128B ,  FREAC7_01 ,  POU3F2_01 ,  NFKAPPAB_01 ,  FOXJ2_01 ,  HFH8_01 ,  NFKB_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128

Cytogenetic Map:

4q13.3

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