QuickView for CXCR2;jsessionid=230884775A61A18AC0C48F15185D6843;jsessionid=9133132EDD5E3E2088A0E74E2683CB66 (gene)
- Gene Symbol:
- Cxcr2
Rattus norvegicus - Full name:
- C-X-C motif chemokine receptor 2
- Synonyms:
- Cmkar2, Il8rb, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, GRO/MGSA receptor, IL-8R B, chemokine (C-X-C motif) receptor 2, chemokine (C-X-C) receptor 2, high affinity interleukin-8 receptor B, interleukin 8 receptor, beta
- Genomic Location:
- Chr 9: 73470943-73477315
- Description:
-
chemokine receptor that binds Il8, GRO/MGSA and neutrophil activating peptide-2; involved in the inflammatory response
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
cytokine binding | interleukin-8 binding | C-X-C chemokine binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | chemokine binding | signaling receptor activity | G-protein coupled chemoattractant receptor activity | cytokine receptor activity | protein binding | interleukin-8 receptor activity | C-C chemokine receptor activity | peptide receptor activity | chemokine receptor activity | G-protein coupled peptide receptor activity | C-C chemokine binding | C-X-C chemokine receptor activity
GO Biological Process
regulation of leukocyte chemotaxis | brain development | positive regulation of locomotion | negative regulation of immune system process | response to cytokine | cell motility | neutrophil activation | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | cellular response to interleukin-8 | morphogenesis of an epithelium | regulation of programmed cell death | establishment of localization | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | regulation of cardiac muscle cell apoptotic process | chemokine-mediated signaling pathway | defense response | nervous system development | cellular chemical homeostasis | positive regulation of cellular component movement | cellular process | interleukin-8-mediated signaling pathway | regulation of cell motility | localization | cellular homeostasis | epithelial tube morphogenesis | metanephric epithelium development | regulation of chemotaxis | negative regulation of apoptotic process | positive regulation of muscle cell apoptotic process | granulocyte chemotaxis | tissue development | regulation of angiogenesis | regulation of cellular process | leukocyte activation | regulation of apoptotic process | positive regulation of neutrophil migration | regulation of cytosolic calcium ion concentration | epithelium development | calcium ion homeostasis | regulation of neutrophil chemotaxis | urogenital system development | head development | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | neutrophil chemotaxis | positive regulation of immune system process | negative regulation of myeloid cell apoptotic process | response to stress | regulation of cell proliferation | tube morphogenesis | negative regulation of neutrophil apoptotic process | inflammatory response to antigenic stimulus | midbrain development | blood circulation | G-protein coupled receptor signaling pathway | kidney development | cell chemotaxis | metal ion homeostasis | leukocyte migration | locomotion | system development | multicellular organism development | cell migration | regulation of granulocyte chemotaxis | positive regulation of chemotaxis | kidney epithelium development | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of cell migration | regulation of vascular permeability | cytokine-mediated signaling pathway | vesicle-mediated transport | regulation of cellular component movement | G-protein coupled chemoattractant receptor activity | second-messenger-mediated signaling | positive regulation of cell migration | cellular response to cytokine stimulus | cation homeostasis | regulation of leukocyte migration | cytokine receptor activity | regulation of muscle cell apoptotic process | cellular cation homeostasis | cell communication | metanephros development | positive regulation of leukocyte chemotaxis | receptor internalization | inflammatory response | leukocyte chemotaxis | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of locomotion | renal system development | calcium-mediated signaling | acute inflammatory response to antigenic stimulus | response to organic substance | tissue morphogenesis | import into cell | positive regulation of vascular permeability | anatomical structure development | cell surface receptor signaling pathway | metabolic process | interleukin-8 receptor activity | regulation of neutrophil migration | negative regulation of programmed cell death | positive regulation of neutrophil chemotaxis | chemical homeostasis | endocytosis | positive regulation of cell death | regulation of myeloid cell apoptotic process | immune response | organic substance metabolic process | animal organ development | metanephric tubule development | positive regulation of leukocyte migration | positive regulation of programmed cell death | ion homeostasis | phospholipase C-activating G-protein coupled receptor signaling pathway | cell activation | positive regulation of cardiac muscle cell apoptotic process | C-C chemokine receptor activity | chemokine receptor activity | signaling | G-protein coupled peptide receptor activity | negative regulation of leukocyte apoptotic process | anatomical structure morphogenesis | regulation of developmental process | receptor-mediated endocytosis | metanephric tubule morphogenesis | developmental process | tube development | receptor metabolic process | cellular defense response | positive regulation of granulocyte chemotaxis | C-X-C chemokine receptor activity | cellular metal ion homeostasis | central nervous system development | acute inflammatory response | immune system process | cellular metabolic process | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | neutrophil migration | chemotaxis | divalent inorganic cation homeostasis | positive regulation of angiogenesis | signal transduction | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | mast cell granule | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | plasma membrane | vacuole | lytic vacuole | membrane-bounded organelle | organelle | lysosome | cell periphery | cell surface | intracellular | membrane
