QuickView for CYH;jsessionid=0AFA9A1CB6138069DE284B8D89367130;jsessionid=77DF2C93E9C081BBD93A0CB990093CAB (gene)

Gene Symbol:

Cma1 Mus musculus

Full name:

chymase 1, mast cell

Synonyms:

MMCP-5, Mcp-5, Mcp5, Mcpt5, chymase, alpha-chymase, mast cell chymase 1, mast cell protease 5, mast cell protease I

Genomic Location:

Chr 14: 56560288-56563498

Description:

This gene encodes a serine protease that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. The encoded preproprotein undergoes proteolytic processing to generate a functi...

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This gene encodes a serine protease that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. The encoded preproprotein undergoes proteolytic processing to generate a functional enzyme with elastase-like activity. Mice lacking the encoded protein exhibit significant attenuation of ischemia-reperfusion injury of the skeletal muscle. This gene is located in a cluster of related mast cell protease genes on chromosome 14.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

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