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QuickView for CYP19A1;jsessionid=978C054C561902D3EFEE91B316A880E5;jsessionid=6E6DA37910860D37B1CA8761A43CADCD (gene)


Gene Symbol:
Cyp19a1 Rattus norvegicus Rattus norvegicus
Full name:
cytochrome P450, family 19, subfamily a, polypeptide 1
Synonyms:
Aromatase, Cyp19, Cyp19a, p450arom, aromatase, CYPXIX, Cytochrome P450, 19, aromatase, P-450AROM, cytochrome P-450AROM, cytochrome P450 19A1, cytochrome P450 19A1-like, cytochrome P450 family 19 subfamily a, cytochrome P450, subfamily 19, estrogen synthase, estrogen synthetase
Genomic Location:
Chr 8: 57651960-57672055
Description:
catalyzes end-step estrogen formation from androgens and aromatization of testosterone to estradiol
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_017085
Protein Names
No proteins found.



GO Molecular Function

cofactor binding | cation binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity

GO Biological Process

regulation of leukocyte chemotaxis | brain development | response to radiation | negative regulation of immune system process | cellular response to glucose stimulus | developmental process involved in reproduction | intracellular signal transduction | regulation of localization | prostate gland growth | response to isoquinoline alkaloid | gonad development | female gonad development | hippocampus development | regulation of immune system process | response to hormone | myeloid cell differentiation | negative regulation of cellular process | response to metal ion | bone development | cell differentiation | negative regulation of tissue remodeling | nervous system development | response to water | response to drug | organ growth | cellular chemical homeostasis | estrogen biosynthetic process | benzene-containing compound metabolic process | glucose homeostasis | estrogen metabolic process | negative regulation of chronic inflammatory response | regulation of lipid transport | regulation of bone remodeling | cellular process | organic substance catabolic process | response to morphine | negative regulation of inflammatory response | regulation of cell motility | cellular homeostasis | dicarboxylic acid metabolic process | developmental growth | reproductive system development | response to estradiol | immune system development | multicellular organismal reproductive process | regulation of estradiol secretion | regulation of chemotaxis | response to growth factor | negative regulation of cell migration | diencephalon development | negative regulation of macrophage migration | response to inorganic substance | negative regulation of cell motility | regulation of cellular process | xenobiotic metabolic process | catabolic process | negative regulation of chemotaxis | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | steroid biosynthetic process | negative regulation of bone resorption | response to cesium ion | urogenital system development | development of primary sexual characteristics | head development | response to stimulus | monocarboxylic acid metabolic process | cellular response to fibroblast growth factor stimulus | cellular response to xenobiotic stimulus | response to stress | hypothalamus development | ovulation cycle | cellular response to hydrostatic pressure | response to glucose | development of primary female sexual characteristics | reproduction | negative regulation of leukocyte chemotaxis | androgen metabolic process | rhythmic process | cellular nitrogen compound metabolic process | positive regulation of hormone secretion | hemopoiesis | regulation of synapse structure or activity | cellular biosynthetic process | response to herbicide | leukocyte differentiation | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | antibiotic metabolic process | cellular glucose homeostasis | hormone biosynthetic process | mammary gland development | response to follicle-stimulating hormone | steroid catabolic process | lipid metabolic process | regulation of hormone levels | regulation of hormone secretion | telencephalon development | positive regulation of secretion | response to ketone | cellular response to stress | response to lipid | cellular response to gonadotropin stimulus | myeloid leukocyte differentiation | response to ammonium ion | dibenzo-p-dioxin metabolic process | regulation of cell migration | small molecule metabolic process | cellular amide metabolic process | regulation of cellular component movement | second-messenger-mediated signaling | luteinization | granulocyte differentiation | cellular ketone metabolic process | biosynthetic process | phthalate metabolic process | lipid biosynthetic process | response to toxic substance | positive regulation of lipid localization | testosterone biosynthetic process | response to xenobiotic stimulus | endocrine system development | regulation of leukocyte migration | ovulation cycle process | response to estrogen | cell communication | androgen catabolic process | female genitalia development | response to testosterone | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | homeostatic process | limbic system development | response to monosaccharide | regulation of locomotion | positive regulation of transport | genitalia development | drug metabolic process | carboxylic acid metabolic process | bile acid metabolic process | calcium-mediated signaling | multicellular organism reproduction | positive regulation of estradiol secretion | development of primary male sexual characteristics | response to organic substance | gland development | hormone catabolic process | male sex differentiation | biphenyl metabolic process | anatomical structure development | regulation of chronic inflammatory response | metabolic process | oxidation-reduction process | male gonad development | melatonin metabolic process | regulation of bone resorption | adrenal gland development | cellular response to carbohydrate stimulus | regulation of tissue remodeling | chemical homeostasis | regulation of secretion | lipid catabolic process | organic substance metabolic process | animal organ development | forebrain development | pallium development | C21-steroid hormone metabolic process | negative regulation of cellular component movement | negative regulation of macrophage chemotaxis | calcineurin-mediated signaling | response to alkaloid | response to gonadotropin | cellular response to follicle-stimulating hormone stimulus | uterus development | steroid metabolic process | regulation of cell communication | signaling | response to organic cyclic compound | organic acid metabolic process | response to hydrostatic pressure | hormone metabolic process | prostate gland development | reproductive structure development | negative regulation of leukocyte migration | developmental process | regulation of transport | response to fibroblast growth factor | response to organonitrogen compound | heterocycle metabolic process | regulation of macrophage chemotaxis | central nervous system development | negative regulation of bone remodeling | response to anesthetic | cellular response to water stimulus | skeletal system development | positive regulation of lipid transport | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | female sex differentiation | cellular response to organic substance | sex differentiation | response to carbohydrate | oxidoreductase activity | aromatase activity | regulation of inflammatory response | carbohydrate homeostasis | negative regulation of locomotion | response to ionizing radiation | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | multicellular organismal process

GO Cellular Component

dendritic spine | exocytic vesicle | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | distal axon | terminal bouton | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | presynapse | cell projection | secretory vesicle | endomembrane system | neuron spine | postsynapse | vesicle | transport vesicle | synaptic vesicle | membrane-bounded organelle | organelle | axon terminus | axon | neuron projection terminus | cytosol | intracellular vesicle | intracellular | membrane