QuickView for CYP1A1;jsessionid=5B4BAB496B1F3AAEDB44A6F2C495DE16;jsessionid=8020AEF0BD182F438FE574BA83FC2DBA;jsessionid=9CE26132C6CF0C013A456254717D1EC1 (gene)
- Gene Symbol:
- Cyp1a1
Rattus norvegicus - Full name:
- cytochrome P450, family 1, subfamily a, polypeptide 1
- Synonyms:
- AHH, AHRR, CP11, CYP1, Cyp45c, Cypc45c, P-450MC, P1-450, P450-C, P450DX, cytochrome P450 1A1, CYPIA1, P450MT2, P450form6, aryl hydrocarbon hydroxylase, cytochrome P1-450, cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c), cytochrome P450, 1a1, cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c), cytochrome P450-C, cytochrome P450MT2, dioxin-inducible, flavoprotein-linked monooxygenase, microsomal monooxygenase, xenobiotic monooxygenase
- Genomic Location:
- Chr 8: 61462207-61468237
- Description:
-
monooxygenase that plays a role in dioxin metabolism and detoxification which is 3-methylcholanthrene-inducible
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | vitamin D 24-hydroxylase activity | cation binding | enzyme binding | steroid hydroxylase activity | iron ion binding | demethylase activity | oxidoreductase activity, acting on diphenols and related substances as donors | catalytic activity | estrogen 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | protein binding | transition metal ion binding | heme binding | flavonoid 3'-monooxygenase activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity
GO Biological Process
response to extracellular stimulus | regulation of cell cycle process | response to virus | response to nutrient levels | response to nematode | response to lipopolysaccharide | regulation of cell cycle G1/S phase transition | isoprenoid biosynthetic process | positive regulation of G1/S transition of mitotic cell cycle | eye development | response to immobilization stress | vitamin D 24-hydroxylase activity | response to metal ion | cell differentiation | response to drug | reactive oxygen species metabolic process | xenobiotic catabolic process | regulation of G1/S transition of mitotic cell cycle | response to antibiotic | hydrogen peroxide biosynthetic process | cellular process | organic substance catabolic process | toxin metabolic process | multicellular organismal reproductive process | response to hypoxia | terpenoid biosynthetic process | regulation of cell cycle | response to inorganic substance | tissue development | porphyrin-containing compound metabolic process | regulation of cellular process | parturition | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | retinoic acid biosynthetic process | hepaticobiliary system development | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | epithelium development | cellular aromatic compound metabolic process | cellular lipid metabolic process | cellular response to metal ion | response to stimulus | monocarboxylic acid metabolic process | regulation of mitotic cell cycle phase transition | lipid hydroxylation | cellular response to xenobiotic stimulus | response to stress | demethylase activity | regulation of cell cycle phase transition | reproduction | cellular response to inorganic substance | response to molecule of bacterial origin | cellular response to organic cyclic compound | cofactor metabolic process | reactive oxygen species biosynthetic process | amine metabolic process | oxidoreductase activity, acting on diphenols and related substances as donors | cellular biosynthetic process | response to iron ion | response to herbicide | retinoid metabolic process | estrogen 16-alpha-hydroxylase activity | response to external biotic stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | antibiotic metabolic process | lipid metabolic process | regulation of hormone levels | positive regulation of cell cycle | positive regulation of mitotic cell cycle | response to lipid | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | 9-cis-retinoic acid biosynthetic process | cofactor biosynthetic process | liver development | dibenzo-p-dioxin metabolic process | small molecule metabolic process | response to nutrient | cell proliferation | biosynthetic process | hepatocyte differentiation | response to hyperoxia | flavonoid metabolic process | digestive tract development | response to vitamin A | lipid biosynthetic process | response to toxic substance | response to xenobiotic stimulus | positive regulation of cell cycle G1/S phase transition | sensory organ development | response to bacterium | retinoic acid metabolic process | aromatic compound catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | lipid modification | response to insecticide | regulation of mitotic cell cycle | drug metabolic process | carboxylic acid metabolic process | multicellular organism reproduction | maternal process involved in parturition | response to organic substance | gland development | digestive system development | response to wounding | anatomical structure development | positive regulation of mitotic cell cycle phase transition | metabolic process | oxidation-reduction process | 9-cis-retinoic acid metabolic process | organic substance metabolic process | response to copper ion | response to vitamin | animal organ development | diterpenoid metabolic process | response to iron(III) ion | camera-type eye development | steroid metabolic process | coumarin metabolic process | response to arsenic-containing substance | response to organic cyclic compound | organic acid metabolic process | dibenzo-p-dioxin catabolic process | hormone metabolic process | response to biotic stimulus | isoprenoid metabolic process | developmental process | positive regulation of cell cycle process | flavonoid 3'-monooxygenase activity | tube development | epithelial cell differentiation | heterocycle metabolic process | demethylation | hydrogen peroxide metabolic process | insecticide metabolic process | cellular metabolic process | cellular response to organic substance | cellular response to copper ion | oxidoreductase activity | aromatase activity | response to food | aging | response to other organism | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane
