QuickView for CYP1A2;jsessionid=F4F5809F9872B691A4E05DAE012E3409;jsessionid=8F7941B210F8DF0B783F8012006B4841 (gene)
- Gene Symbol:
- Cyp1a2
Rattus norvegicus - Full name:
- cytochrome P450, family 1, subfamily a, polypeptide 2
- Synonyms:
- CYPD45, P-450d, RATCYPD45, cytochrome P450 1A2, CYPIA2, Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d), P-448, P450-D, cholesterol 25-hydroxylase, cytochrome P-448, cytochrome P-450d, cytochrome P450, 1a2, cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d), cytochrome P450-D
- Genomic Location:
- Chr 8: 61439090-61445532
- Description:
-
a monooxygenase that may play a role in xenobiotic metabolism
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | enzyme binding | iron ion binding | demethylase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | protein binding | caffeine oxidase activity | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity
GO Biological Process
response to lipopolysaccharide | response to immobilization stress | response to hormone | response to metal ion | respiratory tube development | response to drug | reactive oxygen species metabolic process | generation of precursor metabolites and energy | hydrogen peroxide biosynthetic process | cellular process | organic substance catabolic process | alkaloid metabolic process | toxin metabolic process | response to estradiol | cellular respiration | response to inorganic substance | porphyrin-containing compound metabolic process | regulation of metabolic process | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | cellular response to metal ion | response to stimulus | monocarboxylic acid metabolic process | respiratory system development | cellular response to xenobiotic stimulus | response to stress | demethylase activity | cellular response to inorganic substance | cellular response to cadmium ion | response to molecule of bacterial origin | cofactor metabolic process | reactive oxygen species biosynthetic process | cellular biosynthetic process | drug catabolic process | response to external biotic stimulus | system development | nitrogen compound metabolic process | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | antibiotic metabolic process | steroid catabolic process | lipid metabolic process | regulation of gene expression | response to lipid | cofactor biosynthetic process | dibenzo-p-dioxin metabolic process | small molecule metabolic process | oxidative deethylation | exogenous drug catabolic process | biosynthetic process | response to cadmium ion | response to xenobiotic stimulus | oxidative demethylation | post-embryonic development | response to bacterium | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | drug metabolic process | carboxylic acid metabolic process | monoterpenoid metabolic process | caffeine oxidase activity | response to organic substance | anatomical structure development | metabolic process | oxidation-reduction process | lipid catabolic process | organic substance metabolic process | response to copper ion | animal organ development | lung development | steroid metabolic process | response to organic cyclic compound | organic acid metabolic process | response to biotic stimulus | isoprenoid metabolic process | energy derivation by oxidation of organic compounds | developmental process | tube development | toxin biosynthetic process | heterocycle metabolic process | demethylation | hydrogen peroxide metabolic process | cellular metabolic process | cellular response to copper ion | oxidoreductase activity | aromatase activity | response to other organism | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
