QuickView for CYP1B1;jsessionid=3953E34A356F416CB15FC0085D20B0B2;jsessionid=0635DA906C0EFAE788421E90FF3005D6;jsessionid=B30E8BEFE29661F7E037F1E6C59CD002 (gene)
- Gene Symbol:
- Cyp1b1
Rattus norvegicus - Full name:
- cytochrome P450, family 1, subfamily b, polypeptide 1
- Synonyms:
- cytochrome P450 1B1, CYPIB1, P450RAP, cytochrome P450, subfamily 1B, polypeptide 1, cytochrome P450RAP
- Genomic Location:
- Chr 6: 2545653-2553767
- Description:
-
plays a role in polycyclic aromatic hydrocarbon metabolism in adrenal microsomes
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cofactor binding | cation binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity
GO Biological Process
response to extracellular stimulus | cellular response to luteinizing hormone stimulus | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to nutrient levels | extracellular structure organization | response to cytokine | cell motility | developmental process involved in reproduction | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | cellular response to progesterone stimulus | gonad development | regulation of programmed cell death | eye development | response to luteinizing hormone | nitric oxide biosynthetic process | response to hormone | DNA modification | negative regulation of cellular process | positive regulation of developmental process | response to dexamethasone | cellular response to tumor necrosis factor | nervous system development | response to drug | reactive oxygen species metabolic process | epithelial cell migration | cellular response to cortisol stimulus | benzene-containing compound metabolic process | estrogen metabolic process | positive regulation of cellular component movement | response to cortisol | response to antibiotic | blood vessel morphogenesis | response to organophosphorus | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | regulation of cell motility | localization | toxin metabolic process | positive regulation of reactive oxygen species metabolic process | reproductive system development | response to progesterone | response to estradiol | epithelium migration | multicellular organismal reproductive process | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | response to inorganic substance | response to peptide hormone | tissue development | intrinsic apoptotic signaling pathway | response to hydrogen peroxide | negative regulation of cell motility | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | cellular component organization | cellular lipid metabolic process | endothelial cell-cell adhesion | development of primary sexual characteristics | regulation of vasculature development | response to stimulus | vasculature development | monocarboxylic acid metabolic process | positive regulation of protein metabolic process | negative regulation of cell adhesion | cellular response to xenobiotic stimulus | response to stress | positive regulation of JAK-STAT cascade | endothelial cell migration | ganglion development | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | alcohol metabolic process | regulation of cell proliferation | ovulation cycle | tube morphogenesis | response to peptide | regulation of smooth muscle cell migration | programmed cell death | supramolecular fiber organization | reproduction | positive regulation of vascular endothelial growth factor production | response to alcohol | cardiovascular system development | retinol metabolic process | rhythmic process | cellular nitrogen compound metabolic process | cellular response to toxic substance | extracellular matrix organization | cellular response to organic cyclic compound | reactive oxygen species biosynthetic process | regulation of cell adhesion | cellular biosynthetic process | macromolecule modification | blood vessel development | trabecular meshwork development | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | regulation of neurotransmitter levels | locomotion | organic hydroxy compound metabolic process | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | retinoid metabolic process | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | cellular response to antibiotic | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | cell migration | monooxygenase activity | cellular response to peptide hormone stimulus | response to purine-containing compound | response to follicle-stimulating hormone | positive regulation of smooth muscle cell migration | lipid metabolic process | cellular response to oxidative stress | regulation of hormone levels | regulation of gene expression | response to ketone | cellular response to stress | response to lipid | cellular response to peptide | retina vasculature morphogenesis in camera-type eye | cellular response to gonadotropin stimulus | positive regulation of cellular metabolic process | dibenzo-p-dioxin metabolic process | regulation of nitrogen compound metabolic process | regulation of cell migration | small molecule metabolic process | positive regulation of STAT cascade | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | response to corticosteroid | regulation of cellular component movement | response to nutrient | response to oxidative stress | neurotransmitter metabolic process | positive regulation of cell migration | cellular response to cytokine stimulus | biosynthetic process | regulation of cellular protein metabolic process | angiogenesis | cellular response to glucocorticoid stimulus | regulation of cell adhesion mediated by integrin | response to toxic substance | membrane lipid catabolic process | response to xenobiotic stimulus | endocrine system development | cellular response to corticosteroid stimulus | sensory organ development | cellular response to drug | cell communication | regulation of cellular metabolic process | cellular lipid catabolic process | positive regulation of DNA biosynthetic process | regulation of protein metabolic process | positive regulation of signal transduction | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | regulation of locomotion | regulation of RNA metabolic process | apoptotic signaling pathway | long-chain fatty acid metabolic process | retinal metabolic process | intrinsic apoptotic signaling pathway in response to oxidative stress | drug metabolic process | carboxylic acid metabolic process | cellular aldehyde metabolic process | multicellular organism reproduction | reactive nitrogen species metabolic process | development of primary male sexual characteristics | response to organic substance | gland development | retina development in camera-type eye | regulation of JAK-STAT cascade | male sex differentiation | DNA metabolic process | response to antineoplastic agent | retinal blood vessel morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | metabolic process | membrane lipid metabolic process | regulation of RNA biosynthetic process | oxidation-reduction process | male gonad development | adrenal gland development | cellular response to hydrogen peroxide | positive regulation of cell death | cell adhesion | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | lipid catabolic process | organic substance metabolic process | cell death | animal organ development | response to reactive oxygen species | epithelial cell-cell adhesion | negative regulation of cellular component movement | positive regulation of programmed cell death | diterpenoid metabolic process | cellular response to cAMP | cellular response to steroid hormone stimulus | fatty acid metabolic process | cell-cell adhesion | positive regulation of cytokine production | response to gonadotropin | response to cAMP | camera-type eye development | anatomical structure formation involved in morphogenesis | estrous cycle | icosanoid metabolic process | steroid metabolic process | neurotransmitter biosynthetic process | regulation of cell communication | negative regulation of molecular function | response to arsenic-containing substance | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | response to indole-3-methanol | collagen fibril organization | organic acid metabolic process | regulation of cytokine production | hormone metabolic process | anatomical structure morphogenesis | reproductive structure development | isoprenoid metabolic process | regulation of developmental process | cell death in response to oxidative stress | positive regulation of DNA metabolic process | developmental process | regulation of DNA biosynthetic process | nitric oxide metabolic process | tube development | regulation of reactive oxygen species metabolic process | negative regulation of cell adhesion mediated by integrin | negative regulation of cell proliferation | response to organonitrogen compound | heterocycle metabolic process | regulation of vascular endothelial growth factor production | positive regulation of metabolic process | retina vasculature development in camera-type eye | cellular metabolic process | response to tumor necrosis factor | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cell motility | oxidoreductase activity | response to steroid hormone | aromatase activity | regulation of translation | circulatory system development | arachidonic acid metabolic process | negative regulation of locomotion | positive regulation of angiogenesis | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | mitochondrion | membrane-bounded organelle | nucleus | organelle | intracellular | membrane
