QuickView for CYP2C9;jsessionid=36FCD54D4B13603F300D3370E344E585;jsessionid=890DB861FFCC86326A604E9F8147BF3B (gene)
- Gene Symbol:
- Cyp2c11
Rattus norvegicus - Full name:
- cytochrome P450, subfamily 2, polypeptide 11
- Synonyms:
- CYP2CII, Cyp2c, Cyp2c11l, cytochrome P450 2C11, CYPIIC11, P-450(M-1), P450-UT-A, P450H, UT-2, cytochrome P-450(M-1), cytochrome P450 2C11-like, cytochrome P450, 2c29, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 11, cytochrome P450-UT-2, cytochrome P450-UT-A, cytochrome P450H
- Genomic Location:
- Chr 1: 243281320-243320945
- Description:
-
most abundant member of the p450 xenobiotic-inducible superfamily in non-stimulated liver; metabolizes xenobiotics and testosterone
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | testosterone 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity | arachidonic acid epoxygenase activity
GO Biological Process
response to drug | cellular process | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | response to stimulus | cellular response to xenobiotic stimulus | drug catabolic process | testosterone 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | small molecule metabolic process | exogenous drug catabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | drug metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | organic acid metabolic process | cellular metabolic process | oxidoreductase activity | aromatase activity | arachidonic acid epoxygenase activity
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
