QuickView for CYP51A1;jsessionid=10E106E3A01D6492F8D4A3BF34871034;jsessionid=11DAA59A17F8556A847A9A722FECF30C (gene)
- Gene Symbol:
- Cyp51
Rattus norvegicus - Full name:
- cytochrome P450, family 51
- Synonyms:
- Cyp51a1, RATCP14DM, lanosterol 14-alpha demethylase, CYPLI, Cytochrom P450 Lanosterol 14 alpha-demethylase, LDM, P450-14DM, P45014DM, P450LI, cytochrome P450 51A1, cytochrome P450 Lanosterol 14 alpha-demethylase, cytochrome P450, subfamily 51, cytochrome P450-14DM, cytochrome P45014DM, cytochrome P450LI, sterol 14-alpha demethylase
- Genomic Location:
- Chr 4: 26752677-26771131
- Description:
-
gene amplification is detected in some endometrial carcinomas
- Orthologs:
- Homo sapiens , Mus musculus , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | sterol 14-demethylase activity | cation binding | iron ion binding | demethylase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
sterol 14-demethylase activity | sterol metabolic process | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | demethylase activity | alcohol metabolic process | regulation of steroid biosynthetic process | regulation of steroid metabolic process | organic hydroxy compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | regulation of cholesterol biosynthetic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | sterol biosynthetic process | small molecule metabolic process | regulation of cholesterol metabolic process | biosynthetic process | cholesterol biosynthetic process | lipid biosynthetic process | regulation of lipid biosynthetic process | metabolic process | cholesterol metabolic process | oxidation-reduction process | cholesterol biosynthetic process via 24,25-dihydrolanosterol | organic substance metabolic process | steroid metabolic process | demethylation | regulation of lipid metabolic process | oxidoreductase activity
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane
