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QuickView for Camk2a;jsessionid=1C7B94D95AD51FED352F5D87747EDBA9;jsessionid=4CC20CC8985EE4E08DB29C43A2C73547;jsessionid=A1A8C59867B42C7BD43CACC93BEB9E5E;jsessionid=27477AB657C1D422EAE7F8847DC0FABF (gene)


Gene Symbol:
Camk2a Rattus norvegicus Rattus norvegicus
Full name:
calcium/calmodulin-dependent protein kinase II alpha
Synonyms:
PK2CDD, PKCCD, calcium/calmodulin-dependent protein kinase type II subunit alpha, Ca2+/calmodulin-dependent protein kinase II alpha, alpha CaM kinase II, caM kinase II subunit alpha, caM-kinase II alpha chain, caMK-II subunit alpha, calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha subunit, calcium/calmodulin-dependent protein kinase type II alpha chain
Genomic Location:
Chr 18: 56879247-56948537
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012920
Protein Names
P11275



GO Molecular Function

calcium-dependent protein kinase activity | cation binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | calcium-dependent protein serine/threonine kinase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | GTPase activating protein binding | calmodulin-dependent protein kinase activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | calmodulin binding | metal ion binding | heterocyclic compound binding | glutamate receptor binding | small molecule binding

GO Biological Process

cell morphogenesis | dendritic spine development | regulation of neurogenesis | neuron projection morphogenesis | regulation of cellular localization | positive regulation of apoptotic process | regulation of cell development | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | regulation of mitochondrial membrane permeability involved in apoptotic process | peptidyl-amino acid modification | establishment of localization | response to hormone | regulation of protein localization to membrane | regulation of cardiac muscle cell apoptotic process | cell differentiation | nervous system development | cell part morphogenesis | NMDA selective glutamate receptor signaling pathway | neurogenesis | calcium-dependent protein kinase activity | generation of neurons | membrane organization | cellular process | regulation of neuron migration | regulation of cell motility | localization | cell projection morphogenesis | metal ion transport | neuron development | regulation of neuronal synaptic plasticity | positive regulation of muscle cell apoptotic process | response to peptide hormone | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | cellular response to organonitrogen compound | cellular component organization | response to stimulus | peptidyl-threonine phosphorylation | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | response to stress | postsynaptic neurotransmitter receptor diffusion trapping | response to peptide | protein serine/threonine kinase activity | programmed cell death | cellular localization | divalent metal ion transport | response to ischemia | cell cycle G1/S phase transition | apoptotic mitochondrial changes | G-protein coupled receptor signaling pathway | protein modification process | modulation of chemical synaptic transmission | mitochondrion organization | macromolecule modification | regulation of nucleic acid-templated transcription | regulation of neurotransmitter levels | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | multicellular organism development | cellular response to peptide hormone stimulus | phosphorus metabolic process | peptidyl-threonine autophosphorylation | localization within membrane | regulation of gene expression | regulation of mitochondrial membrane permeability | cellular response to peptide | cell cycle | mitochondrial transport | calcium-dependent protein serine/threonine kinase activity | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | phosphorylation | mitotic cell cycle phase transition | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | cellular response to angiotensin | receptor localization to synapse | mitochondrial membrane organization | regulation of muscle cell apoptotic process | angiotensin-activated signaling pathway | cell communication | regulation of cellular metabolic process | protein-containing complex localization | G1/S transition of mitotic cell cycle | regulation of locomotion | regulation of RNA metabolic process | positive regulation of transport | positive regulation of molecular function | response to angiotensin | neuron differentiation | protein metabolic process | calmodulin-dependent protein kinase activity | response to organic substance | calmodulin dependent kinase signaling pathway | regulation of DNA-binding transcription factor activity | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of protein localization to plasma membrane | regulation of RNA biosynthetic process | calcium ion transport | regulation of secretion | positive regulation of cell death | protein kinase activity | neuron projection development | organic substance metabolic process | cell death | positive regulation of ion transport | positive regulation of NF-kappaB transcription factor activity | positive regulation of programmed cell death | dendrite morphogenesis | positive regulation of cardiac muscle cell apoptotic process | regulation of cell communication | regulation of membrane permeability | signaling | regulation of transcription, DNA-templated | cell development | cellular protein metabolic process | anatomical structure morphogenesis | cation transport | glutamate receptor signaling pathway | dendrite development | regulation of nervous system development | regulation of developmental process | regulation of ion transport | kinase activity | developmental process | organelle organization | peptidyl-serine phosphorylation | regulation of calcium ion transport | cellular protein modification process | regulation of transport | response to organonitrogen compound | cell cycle phase transition | regulation of synaptic plasticity | ion transport | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | ionotropic glutamate receptor signaling pathway | positive regulation of calcium ion transport | signal transduction | regulation of signaling | regulation of neurotransmitter secretion | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

presynaptic membrane | dendritic spine | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | postsynaptic specialization membrane | cell body | cell | neuronal cell body | postsynaptic cytosol | synaptic membrane | cytoplasm | dendrite cytoplasm | intracellular organelle | dendritic tree | presynapse | glutamatergic postsynaptic density | protein-containing complex | cell projection | postsynaptic membrane | neuron spine | postsynapse | plasma membrane bounded cell projection cytoplasm | plasma membrane | postsynaptic density | asymmetric synapse | cytoplasmic region | mitochondrion | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cell periphery | axon | cytosol | calcium- and calmodulin-dependent protein kinase complex | intracellular | cell junction | membrane