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QuickView for DAP5;jsessionid=FB2E7534520E78F90AFC78600E1A4D2E;jsessionid=86E13641386A1DB701830FBCB0DF4955;jsessionid=7C827AC763997687EA5F1B572E73DA75 (gene)


Gene Symbol:
Eif4g2 Mus musculus Mus musculus
Full name:
eukaryotic translation initiation factor 4, gamma 2
Synonyms:
DAP-5, E130105L11Rik, Nat1, Natm1, p97, eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, eif4g2, novel APOBEC-1 target 1, translation repressor Nat1
Genomic Location:
Chr 7: 118211499-118226544
Description:
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G, that contains the binding site...
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
HEN1_02 ACAWNRNSRCGG_UNKNOWN MZF1_01 CDPCR3HD_01 PAX5_01 HSF2_01 SRY_01 SRY_02 MYB_Q6 CATRRAGC_UNKNOWN
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for let-7 Predicted Gene Targets for miR-101 Predicted Gene Targets for miR-139 Predicted Gene Targets for miR-144 Predicted Gene Targets for miR-146 Predicted Gene Targets for miR-19 Predicted Gene Targets for miR-194 Predicted Gene Targets for miR-20 Predicted Gene Targets for miR-208 Predicted Gene Targets for miR-25





GO Molecular Function

nucleic acid binding | mRNA binding | translation initiation factor activity | translation factor activity, RNA binding | organic cyclic compound binding | protein binding | heterocyclic compound binding | RNA binding

GO Biological Process

positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cell development | regulation of autophagy | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | positive regulation of axonogenesis | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular component organization | regulation of translational initiation | peptide biosynthetic process | positive regulation of protein metabolic process | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | translation initiation factor activity | cellular nitrogen compound metabolic process | negative regulation of metabolic process | regulation of cellular component size | regulation of axon extension | cellular biosynthetic process | translational initiation | system development | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | regulation of axonogenesis | regulation of neuron differentiation | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of cell projection organization | cellular amide metabolic process | translation | positive regulation of cell differentiation | translation factor activity, RNA binding | biosynthetic process | regulation of cellular protein metabolic process | positive regulation of dendritic spine development | negative regulation of autophagy | regulation of cellular metabolic process | regulation of protein metabolic process | peptide metabolic process | positive regulation of dendrite development | positive regulation of axon extension | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of growth | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | organic substance metabolic process | gene expression | amide biosynthetic process | regulation of dendrite development | positive regulation of developmental growth | regulation of dendritic spine development | positive regulation of growth | regulation of developmental growth | cellular protein metabolic process | regulation of cell size | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | cellular metabolic process | positive regulation of cell morphogenesis involved in differentiation | regulation of translation | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

neuron projection | cell | cytoplasm | eukaryotic translation initiation factor 4F complex | protein-containing complex | cell projection | axon | cytosol | intracellular