QuickView for DAP5;jsessionid=FB2E7534520E78F90AFC78600E1A4D2E;jsessionid=BF6898520BD110107E2E605F633B855C;jsessionid=64BFAB78DFDB0ACBAE9BAF623CB782A0;jsessionid=3677F49E36C1524A51A02BA1696A390E (gene)
- Gene Symbol:
- EIF4G2
Homo sapiens - Full name:
- eukaryotic translation initiation factor 4 gamma 2
- Synonyms:
- AAG1, DAP5, NAT1, P97, eukaryotic translation initiation factor 4 gamma 2, DAP-5, aging-associated protein 1, death-associated protein 5, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, eukaryotic translation initiation factor 4G-like 1
- Genomic Location:
- Chr 11: 10775169-10787158
- Description:
-
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-139 , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-146 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-194 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-208 , Predicted Gene Targets for miR-25
- Cytogenetic Map:
-
11p15.4
GO Molecular Function
cadherin binding | nucleic acid binding | mRNA binding | translation initiation factor activity | translation factor activity, RNA binding | organic cyclic compound binding | cell adhesion molecule binding | protein binding | heterocyclic compound binding | RNA binding
GO Biological Process
regulation of autophagy | negative regulation of cellular process | cellular process | regulation of cell cycle | negative regulation of cellular metabolic process | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | regulation of translational initiation | peptide biosynthetic process | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | translation initiation factor activity | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | translational initiation | nitrogen compound metabolic process | regulation of gene expression | cell cycle | regulation of nitrogen compound metabolic process | cellular amide metabolic process | translation | translation factor activity, RNA binding | biosynthetic process | regulation of cellular protein metabolic process | negative regulation of autophagy | regulation of cellular metabolic process | regulation of protein metabolic process | peptide metabolic process | protein metabolic process | regulation of growth | cell cycle arrest | metabolic process | organic substance metabolic process | cell death | gene expression | amide biosynthetic process | negative regulation of cell cycle | positive regulation of growth | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of cell growth | cellular metabolic process | regulation of translation | regulation of cellular component organization | macromolecule metabolic process
GO Cellular Component
adherens junction | cell | cytoplasm | cell-cell adherens junction | cell-cell junction | eukaryotic translation initiation factor 4F complex | protein-containing complex | cytosol | intracellular | cell junction | membrane
