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QuickView for DDR1;jsessionid=A62048C9B5C46E575B916215427609E7;jsessionid=7878C8BBD4C895199188BC6754707826 (gene)


Gene Symbol:
Ddr1 Mus musculus Mus musculus
Full name:
discoidin domain receptor family, member 1
Synonyms:
6030432F18, AI323681, CD167a, Cak, Nep, PTK3A, epithelial discoidin domain-containing receptor 1, CD167 antigen-like family member A, cell adhesion kinase, discoidin receptor tyrosine kinase, epithelial discoidin domain receptor 1, protein-tyrosine kinase MPK-6, tyrosine kinase DDR, tyrosine-protein kinase CAK
Genomic Location:
Chr 17: 35818512-35841084
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

transmembrane receptor protein tyrosine kinase activity | protein tyrosine kinase collagen receptor activity | cation binding | transmembrane signaling receptor activity | protein-containing complex binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | collagen binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | collagen receptor activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of ERK1 and ERK2 cascade | cell morphogenesis | cell motility | neuron projection morphogenesis | mammary gland duct morphogenesis | cell-substrate adhesion | morphogenesis of an epithelium | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | establishment of localization | negative regulation of cellular process | cell differentiation | protein tyrosine kinase collagen receptor activity | nervous system development | regulation of extracellular matrix organization | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | generation of neurons | neuron projection extension | cellular process | secretion | localization | cell projection morphogenesis | epithelial tube morphogenesis | negative regulation of signaling | developmental growth | neuron development | female pregnancy | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | tissue development | peptidyl-tyrosine autophosphorylation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | mammary gland morphogenesis | smooth muscle cell-matrix adhesion | response to stimulus | wound healing, spreading of cells | regulation of extracellular matrix disassembly | positive regulation of protein metabolic process | gland morphogenesis | response to stress | regulation of cell proliferation | tube morphogenesis | reproduction | protein modification process | regulation of cell adhesion | macromolecule modification | epiboly | locomotion | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | cell migration | regulation of MAPK cascade | phosphorus metabolic process | mammary gland development | regulation of phosphorylation | wound healing | mammary gland lobule development | axon development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | morphogenesis of an epithelial sheet | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | cell communication | regulation of cellular metabolic process | smooth muscle cell migration | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | protein tyrosine kinase activity | neuron differentiation | protein metabolic process | muscle cell migration | positive regulation of protein modification process | regulation of growth | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | collagen receptor activity | lactation | response to wounding | regulation of intracellular signal transduction | collagen-activated tyrosine kinase receptor signaling pathway | anatomical structure development | developmental growth involved in morphogenesis | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of body fluid levels | negative regulation of programmed cell death | ear development | body fluid secretion | cell adhesion | protein kinase activity | neuron projection development | organic substance metabolic process | animal organ development | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | mammary gland epithelium development | positive regulation of MAPK cascade | collagen-activated signaling pathway | morphogenesis of a branching epithelium | mammary gland alveolus development | regulation of cell communication | negative regulation of signal transduction | signaling | cell-matrix adhesion | cell development | positive regulation of phosphorylation | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | kinase activity | developmental process | regulation of cell growth | cellular protein modification process | tube development | negative regulation of cell proliferation | developmental cell growth | embryo implantation | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | branching involved in mammary gland duct morphogenesis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

brush border | integral component of membrane | cell | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | cell periphery | basolateral plasma membrane | intracellular | membrane | intrinsic component of plasma membrane