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QuickView for DMSA;jsessionid=B2D1EB755E1133E744B4718A2FA4249F;jsessionid=AAE6013ABDF5DD6E500789AF0280D01F (gene)


Gene Symbol:
STAG1 Homo sapiens Homo sapiens
Full name:
stromal antigen 1
Synonyms:
MRD47, SA1, SCC3A, cohesin subunit SA-1, SCC3 homolog 1, nuclear protein stromal antigen 1
Genomic Location:
Chr 3: 137538689-137953935
Description:
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
NFAT_Q4_01 TGGAAA_NFAT_Q4_01 CTTGTAT_MIR381 GATTGGY_NFY_Q6_01 NFMUE1_Q6 OCT1_B TAL1ALPHAE47_01 TCANNTGAY_SREBP1_01 CREBP1CJUN_01 ATF6_01
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3q22.3





GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | chromatin binding | protein binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | regulation of organelle organization | positive regulation of cellular biosynthetic process | cellular process | regulation of mitotic nuclear division | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of mitotic spindle organization | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | chromosome segregation | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of mitotic spindle assembly | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | cell cycle | regulation of spindle assembly | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | cell division | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of mitotic cell cycle | regulation of microtubule-based process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of organelle assembly | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | chromosome, centromeric region | cell | nuclear lumen | cytoplasm | spindle | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | chromatin | microtubule cytoskeleton | spindle pole | cohesin complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear matrix | cytosol | cytoskeleton | mitotic spindle pole | intracellular | mitotic spindle | nuclear periphery | condensed chromosome