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QuickView for DRD1;jsessionid=79023935D86667886B3A7E9A74510861;jsessionid=CF1C1FFC4F0A17BE62DAE4F1ACEB7DA9 (gene)


Gene Symbol:
Drd1 Rattus norvegicus Rattus norvegicus
Full name:
dopamine receptor D1
Synonyms:
D1a, Drd-1, Drd1a, D(1A) dopamine receptor, Dopamine-1A receptor, dopamine receptor D1A
Genomic Location:
Chr 17: 16655120-16658949
Description:
induces dopamine sensitive adenylate cyclase activation; plays a role in regulating food intake
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012546
XM_006253599
XM_006253600
Protein Names
P21669
G3V933



GO Molecular Function

neurotransmitter receptor activity | cation binding | dopamine neurotransmitter receptor activity, coupled via Gs | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | G-protein coupled receptor activity | dopamine binding | D3 dopamine receptor binding | signaling receptor binding | G-protein coupled amine receptor activity | ATPase binding | dopamine receptor binding | signaling receptor activity | protein heterodimerization activity | angiotensin receptor binding | ion binding | organic cyclic compound binding | protein binding | protein phosphatase binding | protein dimerization activity | dopamine neurotransmitter receptor activity | G-protein coupled receptor binding | G-protein coupled serotonin receptor activity | drug binding | phosphatase binding | G-protein alpha-subunit binding

GO Biological Process

positive regulation of cyclase activity | positive regulation of release of sequestered calcium ion into cytosol | response to extracellular stimulus | negative regulation of phosphorylation | brain development | regulation of blood vessel diameter | response to radiation | cellular response to decreased oxygen levels | positive regulation of locomotion | response to nutrient levels | positive regulation of behavior | cell motility | behavioral fear response | regulation of cellular localization | positive regulation of lyase activity | intracellular signal transduction | regulation of localization | subpallium development | response to isoquinoline alkaloid | peptidyl-amino acid modification | hippocampus development | establishment of localization | response to hormone | response to dopamine | astrocyte development | neuron migration | negative regulation of cellular process | negative regulation of kinase activity | social behavior | histone modification | cell differentiation | defense response | nervous system development | response to drug | negative regulation of protein phosphorylation | cellular chemical homeostasis | neurogenesis | positive regulation of phosphate metabolic process | prepulse inhibition | positive regulation of cellular component movement | generation of neurons | response to antibiotic | intracellular transport | dopamine transport | regulation of circadian sleep/wake cycle | cellular process | response to morphine | regulation of cell motility | localization | cellular homeostasis | chromatin organization | positive regulation of synaptic transmission | protein transport | dopamine neurotransmitter receptor activity, coupled via Gs | forebrain cell migration | negative regulation of signaling | visual learning | chemical synaptic transmission | cerebral cortex GABAergic interneuron differentiation | neuron development | walking behavior | regulation of neuronal synaptic plasticity | central nervous system neuron differentiation | synapse assembly | response to estradiol | habituation | positive regulation of membrane potential | cerebral cortex neuron differentiation | multicellular organismal reproductive process | learning | macromolecule localization | response to hypoxia | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | forebrain neuron differentiation | establishment of localization in cell | negative regulation of cellular metabolic process | response to peptide hormone | regulation of behavior | negative regulation of cell motility | regulation of cellular process | regulation of metabolic process | gliogenesis | regulation of cytosolic calcium ion concentration | protein import into nucleus | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | smooth muscle contraction | cellular component organization | calcium ion homeostasis | head development | conditioned taste aversion | G-protein coupled receptor activity | muscle contraction | associative learning | response to stimulus | maternal behavior | regulation of feeding behavior | regulation of long-term synaptic potentiation | positive regulation of protein metabolic process | regulation of blood vessel size | response to cocaine | cellular response to hypoxia | response to stress | intracellular protein transport | positive regulation of cation transmembrane transport | negative regulation of circadian rhythm | monosaccharide transmembrane transport | negative regulation of protein kinase activity | positive regulation of feeding behavior | multicellular organismal homeostasis | regulation of blood circulation | response to peptide | protein localization to nucleus | positive regulation of long-term synaptic potentiation | G-protein coupled amine receptor activity | telencephalon cell migration | peristalsis | reproduction | cellular localization | organic hydroxy compound transport | response to alcohol | regulation of dopamine metabolic process | cellular response to organic cyclic compound | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | neuronal action potential | cellular component assembly | protein modification process | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | macromolecule modification | cell-cell signaling | GABAergic neuron differentiation | synaptic transmission, dopaminergic | metal ion homeostasis | response to ethanol | regulation of catecholamine metabolic process | regulation of membrane potential | locomotion | response to nitrogen compound | regulation of long-term neuronal synaptic plasticity | central nervous system neuron development | regulation of calcium ion transport into cytosol | cellular response to hormone stimulus | response to light stimulus | response to nicotine | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | negative regulation of phosphate metabolic process | positive regulation of calcium ion transmembrane transport | multicellular organism development | negative regulation of catalytic activity | response to activity | cell migration | regulation of synaptic transmission, glutamatergic | cellular response to peptide hormone stimulus | phosphorus metabolic process | response to amino acid | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | histone H3-S10 phosphorylation | adenylate cyclase-activating G-protein coupled receptor signaling pathway | cellular response to insulin stimulus | regulation of catalytic activity | forebrain neuron development | regulation of phosphorylation | nonassociative learning | cellular response to ammonium ion | telencephalon development | cerebral cortex GABAergic interneuron development | regulation of gene expression | organic substance transport | cellular response to stress | response to lipid | nervous system process | cellular response to peptide | synaptic signaling | adult walking behavior | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | adult locomotory behavior | response to ammonium ion | positive regulation of ion transmembrane transport | cellular response to oxygen levels | striatum development | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | peptide transport | hexose transmembrane transport | regulation of cellular component movement | synapse organization | protein localization to organelle | behavioral response to cocaine | import into nucleus | second-messenger-mediated signaling | cerebral cortex GABAergic interneuron migration | cognition | regulation of release of sequestered calcium ion into cytosol | positive regulation of adenylate cyclase activity | positive regulation of cell migration | locomotory behavior | regulation of cellular protein metabolic process | eating behavior | glial cell differentiation | phosphorylation | parental behavior | regulation of calcium ion transmembrane transport | startle response | response to toxic substance | regulation of cyclase activity | response to xenobiotic stimulus | regulation of circadian sleep/wake cycle, sleep | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | protein import | cellular response to drug | dopamine receptor signaling pathway | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | response to catecholamine | astrocyte differentiation | cyclic-nucleotide-mediated signaling | dentate gyrus development | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | limbic system development | regulation of protein phosphorylation | phospholipase C-activating dopamine receptor signaling pathway | regulation of locomotion | histone phosphorylation | regulation of tube size | positive regulation of transport | response to retinoic acid | carbohydrate transport | carbohydrate transmembrane transport | long term synaptic depression | positive regulation of molecular function | calcium-mediated signaling | neuron differentiation | multicellular organism reproduction | response to monoamine | activation of adenylate cyclase activity | multicellular organismal response to stress | fear response | protein metabolic process | positive regulation of protein modification process | response to organic substance | negative regulation of behavior | visual behavior | cAMP-mediated signaling | regulation of kinase activity | establishment of protein localization to organelle | response to insulin | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | response to amine | regulation of vasoconstriction | reproductive behavior | vasodilation | metabolic process | dopamine neurotransmitter receptor activity | mating behavior | regulation of tube diameter | cellular protein localization | glucose import | histone-serine phosphorylation | amide transport | chemical homeostasis | forebrain generation of neurons | behavior | organic substance metabolic process | regulation of sequestering of calcium ion | mating | nuclear transport | grooming behavior | animal organ development | positive regulation of ion transport | forebrain development | pallium development | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | negative regulation of circadian sleep/wake cycle, sleep | ion homeostasis | regulation of phosphate metabolic process | G-protein coupled serotonin receptor activity | response to alkaloid | regulation of ion transmembrane transport | phospholipase C-activating G-protein coupled receptor signaling pathway | establishment of protein localization | orbitofrontal cortex development | temperature homeostasis | drug transport | glucose transmembrane transport | regulation of adenylate cyclase activity | memory | adult behavior | negative regulation of protein metabolic process | interneuron migration from the subpallium to the cortex | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | interneuron migration | transmembrane transport | action potential | signaling | covalent chromatin modification | feeding behavior | glial cell development | response to organic cyclic compound | neuromuscular process | cell development | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | cation transport | cellular macromolecule localization | operant conditioning | positive regulation of calcium ion transport into cytosol | nucleocytoplasmic transport | ammonium transport | regulation of circadian rhythm | G-protein coupled serotonin receptor signaling pathway | regulation of ion transport | developmental process | organelle organization | behavioral defense response | peptidyl-serine phosphorylation | regulation of calcium ion transport | cellular protein modification process | monoamine transport | sensitization | regulation of transport | serotonin receptor signaling pathway | response to organonitrogen compound | cellular metal ion homeostasis | transmission of nerve impulse | negative regulation of synaptic transmission | cellular response to dopamine | central nervous system development | response to anesthetic | positive regulation of metabolic process | chromosome organization | regulation of synaptic plasticity | response to amphetamine | ion transport | adenylate cyclase-activating dopamine receptor signaling pathway | cellular metabolic process | long-term synaptic potentiation | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | response to steroid hormone | response to food | negative regulation of cell death | positive regulation of blood vessel diameter | divalent inorganic cation homeostasis | negative regulation of locomotion | sexual reproduction | positive regulation of calcium ion transport | muscle system process | positive regulation of signaling | cellular response to catecholamine stimulus | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

dendritic spine | non-motile cilium | integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | ciliary membrane | somatodendritic compartment | organelle membrane | cell projection membrane | cell body | cell | neuronal cell body | distal axon | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | dendritic tree | presynapse | nuclear outer membrane-endoplasmic reticulum membrane network | cell projection | endomembrane system | neuron spine | endoplasmic reticulum membrane | postsynapse | plasma membrane | cilium | dendritic spine head | membrane raft | integral component of plasma membrane | membrane-bounded organelle | dendritic shaft | nucleus | organelle | axon terminus | cell periphery | axon | neuron projection terminus | plasma membrane raft | dendritic spine neck | intracellular | caveola | membrane | intrinsic component of plasma membrane