QuickView for DRD4;jsessionid=E44ADEA453EDA7335C97BFD4B0E8FC12;jsessionid=357ECAAEEAE0FF97774091D744BF9DA4 (gene)
- Gene Symbol:
- Drd4
Rattus norvegicus - Full name:
- dopamine receptor D4
- Synonyms:
- D4RA, D(4) dopamine receptor, d(2C) dopamine receptor, dopamine D4 receptor, dopamine receptor 4
- Genomic Location:
- Chr 1: 201485597-201488784
- Description:
-
may play a role in exploratory behavior and motor coordination; may be involved in lesion induced hyperactivity
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
neurotransmitter receptor activity | epinephrine binding | cation binding | transmembrane signaling receptor activity | SH3 domain binding | G-protein coupled receptor activity | dopamine binding | G-protein coupled amine receptor activity | protein domain specific binding | signaling receptor activity | identical protein binding | ion binding | organic cyclic compound binding | protein binding | dopamine neurotransmitter receptor activity | G-protein coupled serotonin receptor activity | norepinephrine binding | drug binding | dopamine neurotransmitter receptor activity, coupled via Gi/Go | metal ion binding
GO Biological Process
long-chain fatty acid transport | response to radiation | chemosensory behavior | behavioral fear response | positive regulation of ion transmembrane transporter activity | regulation of sodium ion transmembrane transporter activity | regulation of cellular localization | negative regulation of peptide secretion | regulation of localization | negative regulation of voltage-gated calcium channel activity | lipid transport | regulation of sodium ion transport | eye development | establishment of localization | response to hormone | negative regulation of cellular process | regulation of MAP kinase activity | positive regulation of sodium ion transmembrane transporter activity | defense response | response to drug | positive regulation of phosphate metabolic process | negative regulation of protein secretion | positive regulation of neurological system process | cellular process | secretion | monocarboxylic acid transport | regulation of cell motility | localization | positive regulation of synaptic transmission | regulation of calcium-mediated signaling | regulation of sodium ion transmembrane transport | negative regulation of smooth muscle cell migration | chemical synaptic transmission | anion transport | learning | positive regulation of protein kinase activity | macromolecule localization | negative regulation of secretion | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | negative regulation of establishment of protein localization | regulation of neurological system process | negative regulation of cell motility | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled receptor activity | regulation of peptide secretion | associative learning | response to stimulus | negative regulation of protein transport | acid secretion | positive regulation of protein metabolic process | response to cocaine | response to stress | positive regulation of cation transmembrane transport | regulation of cell proliferation | circadian rhythm | G-protein coupled amine receptor activity | regulation of smooth muscle cell migration | negative regulation of transporter activity | rhythmic process | regulation of dopamine metabolic process | negative regulation of transport | regulation of protein transport | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | regulation of peptide transport | modulation of chemical synaptic transmission | cell-cell signaling | synaptic transmission, dopaminergic | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | activation of protein kinase activity | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of catecholamine metabolic process | regulation of membrane potential | regulation of neurotransmitter levels | response to nitrogen compound | response to light stimulus | regulation of proton transport | system development | regulation of penile erection | regulation of signal transduction | negative regulation of secretion by cell | modulation of excitatory postsynaptic potential | multicellular organism development | regulation of MAPK cascade | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | arachidonic acid secretion | fatty acid transport | regulation of postsynaptic membrane potential | organic substance transport | response to lipid | nervous system process | synaptic signaling | regulation of sodium:proton antiporter activity | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of smooth muscle cell proliferation | adult locomotory behavior | response to ammonium ion | positive regulation of ion transmembrane transport | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of intracellular signal transduction | regulation of cellular component movement | organic acid transport | behavioral response to cocaine | cognition | olfactory behavior | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | negative regulation of vascular associated smooth muscle cell migration | locomotory behavior | regulation of cellular protein metabolic process | organic anion transport | negative regulation of ion transport | regulation of calcium ion transmembrane transport | response to toxic substance | regulation of voltage-gated calcium channel activity | response to xenobiotic stimulus | sensory organ development | dopamine receptor signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | short-term memory | negative regulation of cation channel activity | positive regulation of transporter activity | negative regulation of calcium ion transport | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of locomotion | negative regulation of vascular smooth muscle cell proliferation | positive regulation of transport | response to histamine | positive regulation of molecular function | activation of MAPK activity | multicellular organismal response to stress | fear response | inhibitory postsynaptic potential | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | retina development in camera-type eye | regulation of kinase activity | regulation of intracellular signal transduction | anatomical structure development | response to amine | cell surface receptor signaling pathway | lipid localization | dopamine neurotransmitter receptor activity | positive regulation of penile erection | regulation of secretion | behavior | negative regulation of ion transmembrane transporter activity | animal organ development | positive regulation of ion transport | positive regulation of sodium ion transport | negative regulation of cellular component movement | regulation of protein secretion | positive regulation of sodium ion transmembrane transport | positive regulation of kinase activity | regulation of phosphate metabolic process | G-protein coupled serotonin receptor activity | response to alkaloid | regulation of ion transmembrane transport | positive regulation of MAPK cascade | positive regulation of excitatory postsynaptic potential | camera-type eye development | memory | adult behavior | olfactory learning | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | adenylate cyclase-inhibiting dopamine receptor signaling pathway | regulation of cell communication | positive regulation of sodium:proton antiporter activity | negative regulation of molecular function | signaling | response to organic cyclic compound | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | carboxylic acid transport | positive regulation of MAP kinase activity | regulation of circadian rhythm | G-protein coupled serotonin receptor signaling pathway | regulation of ion transport | developmental process | behavioral defense response | regulation of calcium ion transport | regulation of transport | negative regulation of cell proliferation | dopamine neurotransmitter receptor activity, coupled via Gi/Go | serotonin receptor signaling pathway | regulation of cation channel activity | response to organonitrogen compound | photoperiodism | response to anesthetic | positive regulation of metabolic process | regulation of calcium ion transmembrane transporter activity | response to amphetamine | ion transport | regulation of protein localization | regulation of smooth muscle cell proliferation | response to steroid hormone | negative regulation of locomotion | positive regulation of signaling | signal transduction | regulation of signaling | regulation of neurotransmitter secretion | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
dendritic spine | integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | organelle membrane | cell body | cell | neuronal cell body | distal axon | intrinsic component of membrane | terminal bouton | cytoplasm | dendritic tree | presynapse | cell projection | neuron spine | postsynapse | plasma membrane | vesicle | cytoplasmic region | integral component of plasma membrane | cell cortex | membrane-bounded organelle | organelle | vesicle membrane | axon terminus | cell periphery | axon | neuron projection terminus | intracellular | membrane | intrinsic component of plasma membrane
