QuickView for DRD5;jsessionid=395AACFE97BCA25BF3ADBDF92C58552B;jsessionid=7520C77661F71FAEE39D655175D59236 (gene)
- Gene Symbol:
- Drd5
Rattus norvegicus - Full name:
- dopamine receptor D5
- Synonyms:
- D1B, D(1B) dopamine receptor, d(5) dopamine receptor, dopamine D5 receptor, dopamine receptor 5
- Genomic Location:
- Chr 14: 77768060-77769487
- Description:
-
dopamine receptor; may play a role in stimulation of adenylyl cyclase, activation of phospholipase C, and phosphatidylinositol phosphate metabolism in the central nervous system
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
neurotransmitter receptor activity | cation binding | dopamine neurotransmitter receptor activity, coupled via Gs | transmembrane signaling receptor activity | G-protein coupled receptor activity | dopamine binding | signaling receptor activity | ion binding | organic cyclic compound binding | protein binding | dopamine neurotransmitter receptor activity | drug binding | G-protein alpha-subunit binding
GO Biological Process
negative regulation of phosphorylation | regulation of blood vessel diameter | response to radiation | regulation of systemic arterial blood pressure by hormone | intracellular signal transduction | regulation of localization | negative regulation of cellular process | negative regulation of kinase activity | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | response to drug | reactive oxygen species metabolic process | negative regulation of protein phosphorylation | cellular process | regulation of cell motility | dopamine neurotransmitter receptor activity, coupled via Gs | negative regulation of signaling | visual learning | chemical synaptic transmission | negative regulation of NAD(P)H oxidase activity | regulation of neuronal synaptic plasticity | multicellular organismal reproductive process | learning | negative regulation of cell migration | negative regulation of cellular metabolic process | negative regulation of cell motility | regulation of cellular process | regulation of metabolic process | cellular response to organonitrogen compound | regulation of systemic arterial blood pressure mediated by a chemical signal | G-protein coupled receptor activity | associative learning | response to stimulus | positive regulation of blood pressure | female mating behavior | regulation of blood vessel size | response to cocaine | response to stress | negative regulation of protein kinase activity | regulation of female receptivity | reproduction | cellular response to organic cyclic compound | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | modulation of chemical synaptic transmission | cell-cell signaling | synaptic transmission, dopaminergic | negative regulation of blood pressure | negative regulation of blood vessel diameter | response to nitrogen compound | regulation of long-term neuronal synaptic plasticity | response to light stimulus | reproductive process | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of phosphorylation | wound healing | nonassociative learning | nervous system process | regulation of blood pressure | synaptic signaling | regulation of systemic arterial blood pressure | response to ammonium ion | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | second-messenger-mediated signaling | cognition | regulation of cellular protein metabolic process | vasoconstriction | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure | response to toxic substance | response to xenobiotic stimulus | regulation of systemic arterial blood pressure by vasopressin | dopamine receptor signaling pathway | endocrine process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | response to catecholamine | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of locomotion | regulation of tube size | long term synaptic depression | multicellular organism reproduction | response to monoamine | response to organic substance | visual behavior | cAMP-mediated signaling | regulation of kinase activity | response to wounding | response to amine | reproductive behavior | metabolic process | dopamine neurotransmitter receptor activity | mating behavior | regulation of tube diameter | behavior | mating | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | regulation of phosphate metabolic process | response to alkaloid | negative regulation of protein metabolic process | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | signaling | regulation of oxidoreductase activity | response to organic cyclic compound | regulation of NAD(P)H oxidase activity | sensitization | negative regulation of oxidoreductase activity | response to organonitrogen compound | transmission of nerve impulse | negative regulation of synaptic transmission | response to anesthetic | regulation of synaptic plasticity | response to amphetamine | adenylate cyclase-activating dopamine receptor signaling pathway | cellular metabolic process | cellular response to organic substance | negative regulation of locomotion | sexual reproduction | cellular response to catecholamine stimulus | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
brush border | dendritic spine | non-motile cilium | integral component of membrane | dendrite | synapse | neuron projection | ciliary membrane | somatodendritic compartment | organelle membrane | cell projection membrane | cell body | cell | neuronal cell body | intrinsic component of membrane | brush border membrane | dendritic tree | cell projection | neuron spine | postsynapse | plasma membrane | cilium | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | axon | intracellular | membrane | intrinsic component of plasma membrane
