QuickView for EDNRA;jsessionid=0CAC7CD07C8B644158743F3BBCEECE2A;jsessionid=1AA62B472DC811DD91BFC18A977C4D3A (gene)
- Gene Symbol:
- Ednra
Rattus norvegicus - Full name:
- endothelin receptor type A
- Synonyms:
- ET-A, ET-AR, Endor, Eta, RGD1559432, endothelin-1 receptor, endothelin A receptor, endothelin-1 receptor-like
- Genomic Location:
- Chr 19: 32046233-32108001
- Description:
-
binds endothelin 1 and induces an increase in intracellular calcium
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | endothelin receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity
GO Biological Process
positive regulation of release of sequestered calcium ion into cytosol | regulation of leukocyte chemotaxis | regulation of ERK1 and ERK2 cascade | respiratory gaseous exchange | regulation of blood vessel diameter | positive regulation of locomotion | renal filtration | response to lipopolysaccharide | regulation of cellular localization | intracellular signal transduction | regulation of localization | morphogenesis of an epithelium | response to isoquinoline alkaloid | regulation of programmed cell death | vascular smooth muscle contraction | establishment of localization | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | response to drug | cellular chemical homeostasis | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | tonic smooth muscle contraction | mesenchyme development | blood vessel morphogenesis | fibroblast proliferation | histamine secretion | artery smooth muscle contraction | cellular process | secretion | response to morphine | regulation of cell motility | localization | cellular homeostasis | epithelial tube morphogenesis | glomerular filtration | azole transport | multicellular organismal reproductive process | regulation of chemotaxis | negative regulation of apoptotic process | response to hypoxia | positive regulation of nitrogen compound metabolic process | tissue development | histamine transport | autonomic nervous system development | regulation of cellular process | parturition | regulation of apoptotic process | regulation of metabolic process | positive regulation of neutrophil migration | regulation of cytosolic calcium ion concentration | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | smooth muscle contraction | calcium ion homeostasis | regulation of neutrophil chemotaxis | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | head development | G-protein coupled receptor activity | muscle contraction | branching involved in blood vessel morphogenesis | response to stimulus | vasculature development | cellular response to mechanical stimulus | mesenchymal cell development | positive regulation of immune system process | positive regulation of protein metabolic process | regulation of blood vessel size | response to stress | positive regulation of cation transmembrane transport | regulation of cell proliferation | tube morphogenesis | reproduction | cardiovascular system development | response to molecule of bacterial origin | blood circulation | G-protein coupled receptor signaling pathway | regulation of odontogenesis | embryo development | metal ion homeostasis | blood vessel development | negative regulation of blood vessel diameter | response to nitrogen compound | regulation of calcium ion transport into cytosol | response to external biotic stimulus | system development | response to oxygen levels | reproductive process | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | multicellular organism development | regulation of MAPK cascade | positive regulation of inflammatory response | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of granulocyte chemotaxis | regulation of phosphorylation | positive regulation of chemotaxis | organic substance transport | response to lipid | nervous system process | copulation | regulation of blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | response to ammonium ion | positive regulation of ion transmembrane transport | enteric nervous system development | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | endothelin receptor activity | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of release of sequestered calcium ion into cytosol | stem cell differentiation | positive regulation of cell migration | cell proliferation | sensory perception of pain | endothelin receptor signaling pathway | regulation of cellular protein metabolic process | vasoconstriction | angiogenesis | regulation of calcium ion transmembrane transport | positive regulation of odontogenesis | response to xenobiotic stimulus | cation homeostasis | regulation of leukocyte migration | response to bacterium | chordate embryonic development | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of leukocyte chemotaxis | regulation of protein metabolic process | positive regulation of signal transduction | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | protein kinase C-activating G-protein coupled receptor signaling pathway | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of tube size | positive regulation of transport | multicellular organism reproduction | maternal process involved in parturition | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | Rho protein signal transduction | branching morphogenesis of an epithelial tube | response to mechanical stimulus | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | mesenchymal cell differentiation | regulation of neutrophil migration | negative regulation of programmed cell death | smooth muscle cell proliferation | positive regulation of neutrophil chemotaxis | regulation of tube diameter | chemical homeostasis | regulation of sequestering of calcium ion | mating | regulation of glucose transmembrane transport | animal organ development | positive regulation of ion transport | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | regulation of ion transmembrane transport | phospholipase C-activating G-protein coupled receptor signaling pathway | renal system process | positive regulation of MAPK cascade | stem cell development | morphogenesis of a branching epithelium | anatomical structure formation involved in morphogenesis | sensory perception | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | muscle cell proliferation | signaling | G-protein coupled peptide receptor activity | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | cation transport | positive regulation of calcium ion transport into cytosol | response to biotic stimulus | ammonium transport | regulation of developmental process | regulation of ion transport | developmental process | regulation of calcium ion transport | tube development | regulation of transport | Ras protein signal transduction | neurotransmitter transport | positive regulation of kidney development | response to organonitrogen compound | neural crest cell differentiation | positive regulation of granulocyte chemotaxis | cellular metal ion homeostasis | response to anesthetic | in utero embryonic development | positive regulation of metabolic process | ion transport | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | circulatory system development | regulation of inflammatory response | aging | divalent inorganic cation homeostasis | penile erection | neural crest cell development | sexual reproduction | positive regulation of calcium ion transport | muscle system process | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | organelle membrane | nuclear membrane | cell | intrinsic component of membrane | intracellular organelle | membrane microdomain | endomembrane system | plasma membrane | nuclear envelope | membrane raft | T-tubule | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane
