QuickView for EGFR;jsessionid=905410D974C2C275ED72E0A203A028A4;jsessionid=7F6E58F454CB8355B9F533845AEDEC25 (gene)
- Gene Symbol:
- EGFR
Bos taurus - Full name:
- epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
- Synonyms:
- N/A
- Genomic Location:
- Chr 22: 612700-790626
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
CEBPA_01 , NKX25_01 , HLF_01 , P53_02 , TITF1_Q3 , PAX2_02 , AFP1_Q6 , CEBPDELTA_Q6 , P53_DECAMER_Q2 , CEBP_Q2_01
GO Molecular Function
actin binding | transmembrane receptor protein tyrosine kinase activity | actin filament binding | epidermal growth factor-activated receptor activity | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | growth factor binding | molecular function regulator | catalytic activity | chromatin binding | ATP binding | ubiquitin-like protein ligase binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | identical protein binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | hormone binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | protein phosphatase binding | ubiquitin protein ligase binding | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | nitric-oxide synthase regulator activity | protein kinase activity | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | phosphatase binding | epidermal growth factor binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of cyclin-dependent protein serine/threonine kinase activity | regulation of ERK1 and ERK2 cascade | brain development | molting cycle | response to radiation | cell morphogenesis | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | cell motility | developmental process involved in reproduction | regulation of cellular localization | regulation of localization | regulation of cell cycle G1/S phase transition | morphogenesis of an epithelium | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | eye development | response to hormone | negative regulation of cellular process | regulation of MAP kinase activity | response to metal ion | regulation of protein localization to membrane | positive regulation of epithelial cell proliferation | positive regulation of fibroblast proliferation | nervous system development | regulation of G1/S transition of mitotic cell cycle | positive regulation of phosphate metabolic process | regulation of DNA replication | peptidyl-tyrosine phosphorylation | positive regulation of cellular component movement | salivary gland morphogenesis | regulation of DNA repair | epidermal growth factor-activated receptor activity | positive regulation of cellular biosynthetic process | cellular process | regulation of production of miRNAs involved in gene silencing by miRNA | regulation of cell motility | localization | forebrain cell migration | positive regulation of peptidyl-serine phosphorylation | reproductive system development | response to estradiol | positive regulation of protein kinase activity | negative regulation of apoptotic process | digestive tract morphogenesis | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | regulation of canonical Wnt signaling pathway | tissue development | regulation of cell differentiation | regulation of protein kinase B signaling | peptidyl-tyrosine autophosphorylation | regulation of cellular process | positive regulation of cell growth | negative regulation of cardiocyte differentiation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | positive regulation of cyclin-dependent protein kinase activity | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | epithelium development | cellular response to organonitrogen compound | regulation of gene silencing by miRNA | cellular component organization | positive regulation of response to DNA damage stimulus | cellular response to metal ion | response to UV | head development | response to stimulus | positive regulation of NIK/NF-kappaB signaling | regulation of cellular protein localization | regulation of mitotic cell cycle phase transition | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | gland morphogenesis | response to stress | positive regulation of nitric oxide mediated signal transduction | positive regulation of cellular protein localization | regulation of cell proliferation | tube morphogenesis | regulation of cell cycle phase transition | telencephalon cell migration | positive regulation of protein kinase C activity | reproduction | cellular response to inorganic substance | cellular response to cadmium ion | regulation of gene silencing | cellular response to organic cyclic compound | ERBB signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | embryo development | macromolecule modification | positive regulation of production of miRNAs involved in gene silencing by miRNA | molecular function regulator | embryonic placenta development | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | locomotion | response to nitrogen compound | cellular response to hormone stimulus | response to light stimulus | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | cell migration | response to UV-A | positive regulation of DNA replication | regulation of MAPK cascade | phosphorus metabolic process | response to amino acid | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | cellular response to oxidative stress | regulation of phosphorylation | regulation of nitric-oxide synthase activity | telencephalon development | positive regulation of cell cycle | positive regulation of protein localization to plasma membrane | regulation of gene expression | cellular response to stress | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | eyelid development in camera-type eye | animal organ morphogenesis | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | morphogenesis of an epithelial fold | response to oxidative stress | positive regulation of cell migration | cell proliferation | response to cadmium ion | regulation of cellular protein metabolic process | phosphorylation | digestive tract development | epidermis development | skin development | cerebral cortex cell migration | cellular response to amino acid stimulus | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of protein localization to membrane | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | cerebral cortex development | regulation of mitotic cell cycle | protein tyrosine kinase activity | positive regulation of molecular function | protein metabolic process | regulation of fibroblast proliferation | positive regulation of protein modification process | regulation of growth | hair cycle | response to organic substance | gland development | tissue morphogenesis | digestive system development | regulation of kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of protein catabolic process | regulation of protein localization to plasma membrane | regulation of RNA biosynthetic process | negative regulation of programmed cell death | embryonic organ development | nitric-oxide synthase regulator activity | hair cycle process | cell adhesion | regulation of gene silencing by RNA | regulation of response to DNA damage stimulus | protein kinase activity | cellular response to reactive oxygen species | organic substance metabolic process | animal organ development | response to reactive oxygen species | forebrain development | pallium development | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | skin epidermis development | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | cell-cell adhesion | regulation of JNK cascade | positive regulation of MAPK cascade | camera-type eye development | positive regulation of canonical Wnt signaling pathway | regulation of peptidyl-serine phosphorylation | negative regulation of protein catabolic process | negative regulation of protein metabolic process | cellular response to estradiol stimulus | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | positive regulation of growth | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | response to organic cyclic compound | regulation of epithelial cell proliferation | regulation of production of small RNA involved in gene silencing by RNA | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | anatomical structure morphogenesis | positive regulation of MAP kinase activity | reproductive structure development | positive regulation of gene silencing by miRNA | regulation of developmental process | positive regulation of DNA metabolic process | kinase activity | developmental process | regulation of cell growth | cellular protein modification process | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | in utero embryonic development | positive regulation of metabolic process | regulation of nitric oxide mediated signal transduction | positive regulation of Wnt signaling pathway | cellular metabolic process | placenta development | cellular response to organic substance | regulation of protein localization | exocrine system development | regulation of cell death | positive regulation of cell motility | salivary gland development | negative regulation of cell death | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of signaling | hair follicle development | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | positive regulation of DNA repair | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | early endosome membrane | late endosome | organelle membrane | cytoplasmic vesicle | cell | multivesicular body | multivesicular body, internal vesicle | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | endosome membrane | protein-containing complex | endomembrane system | plasma membrane | membrane raft | vesicle | perinuclear region of cytoplasm | endosome | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | early endosome | basolateral plasma membrane | multivesicular body, internal vesicle lumen | intracellular vesicle | cell surface | endocytic vesicle | intracellular | membrane | vesicle lumen
