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QuickView for ENG;jsessionid=DA8418571AF35E1CD8994477639793A5;jsessionid=232ACA3D910F62FC047133E43092BCD8;jsessionid=FA8E9A422B40005B991DDBF284DAB5E8 (gene)


Gene Symbol:
Eng Rattus norvegicus Rattus norvegicus
Full name:
endoglin
Synonyms:
endoglin
Genomic Location:
N/A
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Canis lupus familiaris Bos taurus Pan troglodytes Gallus gallus
External Links:
Entrez Gene


Transcripts Names
NM_001010968
XM_017591971
Protein Names
Q3KR75
Q6Q3E8



GO Molecular Function

transforming growth factor beta binding | cytokine binding | transforming growth factor beta-activated receptor activity | BMP binding | transmembrane signaling receptor activity | galactose binding | transforming growth factor beta receptor binding | signaling receptor binding | carbohydrate derivative binding | cytokine receptor binding | protein serine/threonine kinase activity | growth factor binding | monosaccharide binding | catalytic activity | signaling receptor activity | identical protein binding | type I transforming growth factor beta receptor binding | carbohydrate binding | protein binding | protein homodimerization activity | transmembrane receptor protein serine/threonine kinase activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | glycosaminoglycan binding | transferase activity | type II transforming growth factor beta receptor binding | transforming growth factor beta receptor, cytoplasmic mediator activity | kinase activity | small molecule binding

GO Biological Process

negative regulation of phosphorylation | ventricular cardiac muscle tissue morphogenesis | positive regulation of macromolecule biosynthetic process | detection of stimulus | extracellular structure organization | cell motility | muscle tissue development | endothelial cell development | regulation of cell development | regulation of localization | positive regulation of collagen metabolic process | heart trabecula morphogenesis | morphogenesis of an epithelium | regulation of programmed cell death | smooth muscle cell differentiation | establishment of localization | response to hormone | regulation of transforming growth factor beta receptor signaling pathway | cell migration involved in endocardial cushion formation | dorsal aorta development | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | bone development | regulation of cardiac muscle cell apoptotic process | cell differentiation | endothelial cell differentiation | nervous system development | epithelial to mesenchymal transition | response to drug | transforming growth factor beta-activated receptor activity | negative regulation of protein phosphorylation | epithelial to mesenchymal transition involved in endocardial cushion formation | positive regulation of phosphate metabolic process | mesenchyme development | cardiac atrium morphogenesis | blood vessel morphogenesis | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | secretion | establishment of blood-brain barrier | regulation of cell motility | localization | epithelial tube morphogenesis | heart morphogenesis | negative regulation of signaling | determination of left/right symmetry | positive regulation of epithelial to mesenchymal transition | positive regulation of pathway-restricted SMAD protein phosphorylation | negative regulation of nucleic acid-templated transcription | response to hypoxia | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | positive regulation of muscle cell differentiation | muscle structure development | muscle cell differentiation | negative regulation of cell motility | regulation of angiogenesis | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | trabecula morphogenesis | positive regulation of cellular protein metabolic process | regulation of neural crest cell differentiation | negative regulation of protein autophosphorylation | epithelium development | cellular component organization | ventricular trabecula myocardium morphogenesis | response to transforming growth factor beta | sprouting angiogenesis | muscle organ morphogenesis | branching involved in blood vessel morphogenesis | regulation of vasculature development | response to stimulus | positive regulation of blood pressure | vasculature development | muscle cell development | cellular response to mechanical stimulus | positive regulation of protein metabolic process | determination of heart left/right asymmetry | establishment of endothelial blood-brain barrier | response to stress | regulation of cell proliferation | vascular smooth muscle cell differentiation | atrial cardiac muscle tissue morphogenesis | tube morphogenesis | cardiac muscle tissue development | muscle tissue morphogenesis | epithelial cell development | protein serine/threonine kinase activity | extracellular matrix constituent secretion | central nervous system vasculogenesis | secretion by cell | cardiovascular system development | cardiac ventricle morphogenesis | extracellular matrix organization | blood circulation | negative regulation of metabolic process | positive regulation of BMP signaling pathway | positive regulation of RNA biosynthetic process | protein modification process | detection of oxygen | embryo development | regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | macromolecule modification | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | cell chemotaxis | blood vessel development | regulation of nucleic acid-templated transcription | locomotion | endocardial cushion development | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | endothelium development | detection of chemical stimulus | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | cell migration | regulation of BMP signaling pathway | phosphorus metabolic process | regulation of collagen biosynthetic process | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of phosphorylation | wound healing | regulation of nitric-oxide synthase activity | cardiac epithelial to mesenchymal transition | artery development | determination of bilateral symmetry | regulation of gene expression | outflow tract morphogenesis | response to lipid | regulation of blood pressure | endocardial cushion morphogenesis | regulation of protein autophosphorylation | embryonic heart tube morphogenesis | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | regulation of smooth muscle cell differentiation | atrioventricular canal morphogenesis | animal organ morphogenesis | establishment of endothelial barrier | regulation of nitrogen compound metabolic process | regulation of cell migration | cardiac jelly development | enzyme linked receptor protein signaling pathway | cardiac atrium development | positive regulation of intracellular signal transduction | response to corticosteroid | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of smooth muscle cell differentiation | positive regulation of cell differentiation | regulation of cell proliferation involved in heart morphogenesis | regulation of cellular protein metabolic process | angiogenesis | mesenchyme morphogenesis | phosphorylation | cardiac septum morphogenesis | detection of hypoxia | heart looping | protein phosphorylation | phosphate-containing compound metabolic process | regulation of muscle cell apoptotic process | striated muscle tissue development | cardiac muscle tissue morphogenesis | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of collagen metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | chronological cell aging | heart development | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | regulation of stem cell differentiation | regulation of cellular response to growth factor stimulus | cell aging | embryonic morphogenesis | positive regulation of systemic arterial blood pressure | smooth muscle tissue development | venous blood vessel development | cell migration involved in heart development | cellular response to transforming growth factor beta stimulus | negative regulation of monooxygenase activity | embryonic organ morphogenesis | negative regulation of epithelial cell proliferation | protein metabolic process | transmembrane receptor protein serine/threonine kinase activity | cardiac ventricle development | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | artery morphogenesis | branching morphogenesis of an epithelial tube | response to wounding | response to mechanical stimulus | regulation of animal organ morphogenesis | negative regulation of pathway-restricted SMAD protein phosphorylation | regulation of intracellular signal transduction | ventricular cardiac muscle tissue development | embryonic heart tube development | anatomical structure development | cell surface receptor signaling pathway | aorta development | metabolic process | mesenchymal cell differentiation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | negative regulation of endothelial cell proliferation | endocardial cushion to mesenchymal transition | protein kinase activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of endothelial cell proliferation | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | dorsal aorta morphogenesis | regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | regulation of heart morphogenesis | regulation of phosphate metabolic process | aorta morphogenesis | morphogenesis of a branching epithelium | transforming growth factor beta receptor signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | endocardial cushion formation | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of developmental process | kinase activity | developmental process | regulation of muscle cell differentiation | negative regulation of nitric-oxide synthase activity | vascular smooth muscle cell development | cardiac septum development | cellular protein modification process | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | negative regulation of oxidoreductase activity | positive regulation of nucleic acid-templated transcription | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | venous blood vessel morphogenesis | regulation of epithelial to mesenchymal transition | cardiac chamber development | central nervous system development | positive regulation of metabolic process | positive regulation of vascular smooth muscle cell differentiation | skeletal system development | positive regulation of collagen biosynthetic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | response to steroid hormone | circulatory system development | aging | chemotaxis | negative regulation of locomotion | positive regulation of angiogenesis | extracellular matrix disassembly | positive regulation of cardiac epithelial to mesenchymal transition | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | regulation of pathway-restricted SMAD protein phosphorylation | positive regulation of gene expression | outflow tract septum morphogenesis | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | endothelial microparticle | external side of plasma membrane | receptor complex | protein-containing complex | plasma membrane | extracellular region | extracellular space | cell periphery | blood microparticle | cell surface | membrane