QuickView for ERCC2;jsessionid=A230E78121AA7A91C54FDDBD660DDB57;jsessionid=2CC198C4A2215E3ED4B84E3570E05122;jsessionid=C76511DB3ACA4BCCEDC8098C2384E744 (gene)
- Gene Symbol:
- Ercc2
Rattus norvegicus - Full name:
- ERCC excision repair 2, TFIIH core complex helicase subunit
- Synonyms:
- TFIIH basal transcription factor complex helicase XPD subunit, excision repair cross-complementation group 2, excision repair cross-complementing rodent repair deficiency, complementation group 2, rCG54110-like
- Genomic Location:
- N/A
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Bos taurus , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
nucleic acid binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | protein serine/threonine kinase activity | ATPase activity | pyrophosphatase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | ATP-dependent 5'-3' DNA helicase activity | ATP binding | protein N-terminus binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | damaged DNA binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA helicase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | hydrolase activity, acting on acid anhydrides | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | kinase activity | heterocyclic compound binding | 5'-3' DNA helicase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | protein C-terminus binding | small molecule binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | molting cycle | response to radiation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | extracellular structure organization | erythrocyte homeostasis | myeloid cell differentiation | cell differentiation | bone mineralization | nervous system development | multicellular organism growth | positive regulation of DNA recombination | neurogenesis | erythrocyte maturation | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | axon ensheathment | cell maturation | developmental growth | immune system development | response to hypoxia | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | myeloid cell development | central nervous system myelination | tissue development | regulation of binding | DNA geometric change | regulation of cellular process | regulation of metabolic process | gliogenesis | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | central nervous system myelin formation | cellular component organization | ATP-dependent DNA helicase activity | response to UV | response to stimulus | regulation of DNA recombination | regulation of mitotic cell cycle phase transition | oligodendrocyte development | chromosome segregation | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell cycle phase transition | ensheathment of neurons | hematopoietic progenitor cell differentiation | protein serine/threonine kinase activity | axon ensheathment in central nervous system | programmed cell death | hair follicle maturation | nucleotide-excision repair, DNA duplex unwinding | cellular nitrogen compound metabolic process | extracellular matrix organization | regulation of DNA binding | nucleic acid phosphodiester bond hydrolysis | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | protein modification process | RNA polymerase II CTD heptapeptide repeat kinase activity | cellular biosynthetic process | embryo development | macromolecule modification | myeloid cell homeostasis | DNA repair | hair cell differentiation | regulation of nucleic acid-templated transcription | apoptotic process | ATP-dependent 5'-3' DNA helicase activity | response to light stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | myelination | multicellular organism development | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | UV protection | regulation of transcription by RNA polymerase II | response to oxidative stress | positive regulation of mitotic recombination | epidermal cell differentiation | homeostasis of number of cells | stem cell differentiation | cell proliferation | biosynthetic process | cell division | aromatic compound biosynthetic process | glial cell differentiation | phosphorylation | epidermis development | skin development | protein phosphorylation | post-embryonic development | erythrocyte development | phosphate-containing compound metabolic process | DNA duplex unwinding | chordate embryonic development | regulation of cellular metabolic process | homeostatic process | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of mitotic cell cycle | DNA helicase activity | positive regulation of molecular function | neuron differentiation | protein metabolic process | hair cycle | DNA metabolic process | nucleotide-excision repair, DNA incision | anatomical structure development | metabolic process | nucleotide-excision repair | regulation of RNA biosynthetic process | developmental maturation | embryonic organ development | regulation of mitotic recombination | oligodendrocyte differentiation | hair cycle process | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | cell death | animal organ development | gene expression | skin epidermis development | biomineral tissue development | positive regulation of binding | transcription, DNA-templated | embryonic cleavage | anatomical structure formation involved in morphogenesis | transcription-coupled nucleotide-excision repair | regulation of transcription, DNA-templated | glial cell development | cell development | positive regulation of DNA binding | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | hematopoietic stem cell differentiation | positive regulation of DNA metabolic process | kinase activity | developmental process | organelle organization | erythrocyte differentiation | cellular protein modification process | myelin assembly | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | DNA conformation change | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | spinal cord development | in utero embryonic development | positive regulation of metabolic process | chromosome organization | ossification | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | 5'-3' DNA helicase activity | aging | hair follicle development | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | MMXD complex | protein kinase complex | cell | nuclear lumen | transcription factor complex | cytoplasm | spindle | intracellular organelle | carboxy-terminal domain protein kinase complex | protein-containing complex | nucleoplasm | nuclear cyclin-dependent protein kinase holoenzyme complex | transferase complex | microtubule cytoskeleton | serine/threonine protein kinase complex | membrane-bounded organelle | holo TFIIH complex | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | core TFIIH complex | cytosol | cytoskeleton | intracellular | cyclin-dependent protein kinase activating kinase holoenzyme complex | RNA polymerase II, holoenzyme
