QuickView for ERCC2;jsessionid=A230E78121AA7A91C54FDDBD660DDB57;jsessionid=2CC198C4A2215E3ED4B84E3570E05122;jsessionid=7F602042B3896CEAC57D24AE6334634A (gene)
- Gene Symbol:
- Xpd
D. melanogaster - Full name:
- Xeroderma pigmentosum D
- Synonyms:
- CG9433, DhR3, DhXPD, DmelCG9433, Dmel_CG9433, DmXPD, Xpd, XPD, XPD/ERCC2
- Genomic Location:
- Chr 2R: 17058508-17062009
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Bos taurus , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
nucleic acid binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | protein serine/threonine kinase activity | ATPase activity | pyrophosphatase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | ATP-dependent 5'-3' DNA helicase activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | damaged DNA binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA helicase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | hydrolase activity, acting on acid anhydrides | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | transcription factor activity, core RNA polymerase binding | kinase activity | heterocyclic compound binding | 5'-3' DNA helicase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | response to radiation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | regulation of syncytial blastoderm mitotic cell cycle | negative regulation of cellular process | positive regulation of DNA recombination | regulation of organelle organization | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | regulation of mitotic nuclear division | regulation of embryonic development | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | DNA geometric change | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | cellular component organization | ATP-dependent DNA helicase activity | response to UV | response to stimulus | regulation of DNA recombination | regulation of mitotic cell cycle phase transition | response to stress | negative regulation of G2/M transition of mitotic cell cycle | cellular nitrogen compound biosynthetic process | regulation of cell cycle phase transition | protein serine/threonine kinase activity | nucleotide-excision repair, DNA duplex unwinding | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | positive regulation of RNA biosynthetic process | protein modification process | RNA polymerase II CTD heptapeptide repeat kinase activity | cellular biosynthetic process | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | ATP-dependent 5'-3' DNA helicase activity | regulation of cell cycle G2/M phase transition | response to light stimulus | nitrogen compound metabolic process | negative regulation of mitotic cell cycle phase transition | negative regulation of cell cycle G2/M phase transition | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of mitotic cell cycle, embryonic | regulation of gene expression | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | response to oxidative stress | positive regulation of mitotic recombination | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | DNA duplex unwinding | regulation of cellular metabolic process | DNA-templated transcriptional open complex formation | regulation of RNA metabolic process | regulation of mitotic cell cycle | DNA helicase activity | protein metabolic process | DNA metabolic process | nucleotide-excision repair, DNA incision | metabolic process | nucleotide-excision repair | regulation of RNA biosynthetic process | regulation of mitotic recombination | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | negative regulation of cell cycle | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of developmental process | positive regulation of DNA metabolic process | transcription factor activity, core RNA polymerase binding | kinase activity | organelle organization | cellular protein modification process | transcriptional open complex formation at RNA polymerase II promoter | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | DNA conformation change | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | promoter clearance from RNA polymerase II promoter | cellular metabolic process | negative regulation of cell cycle process | 5'-3' DNA helicase activity | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
polytene chromosome interband | nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | polytene chromosome | RNA polymerase II transcription factor complex | protein kinase complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | carboxy-terminal domain protein kinase complex | protein-containing complex | polytene chromosome puff | nucleoplasm | transferase complex | serine/threonine protein kinase complex | membrane-bounded organelle | holo TFIIH complex | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | RNA polymerase complex | membrane-enclosed lumen | core TFIIH complex | intracellular | RNA polymerase II, holoenzyme
