QuickView for ESR1;jsessionid=0DB6BE8A5883FF19F872749310D60664;jsessionid=AF0807D7198946A688747D0B5E7F0842 (gene)

GO Molecular Function

sequence-specific DNA binding | beta-catenin binding | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | hormone receptor binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | protein kinase binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | lipid binding | estrogen receptor binding | signaling receptor binding | transcription coactivator binding | TFIIB-class transcription factor binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | steroid hormone receptor activity | chromatin binding | ATPase binding | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | identical protein binding | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | nuclear hormone receptor binding | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | estrogen receptor activity | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | TBP-class protein binding | RNA polymerase II transcription factor binding | estrogen response element binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transition metal ion binding | steroid hormone receptor binding | steroid binding | transcription cofactor binding | metal ion binding | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | developmental process involved in reproduction | ovarian follicle development | mammary gland duct morphogenesis | prostate gland growth | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | gonad development | regulation of programmed cell death | female gonad development | regulation of immune system process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | epithelial cell proliferation involved in mammary gland duct elongation | negative regulation of RNA biosynthetic process | cell differentiation | positive regulation of fibroblast proliferation | organ growth | negative regulation of gene silencing by RNA | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | regulation of transcription initiation from RNA polymerase II promoter | cellular process | regulation of branching involved in prostate gland morphogenesis | regulation of production of miRNAs involved in gene silencing by miRNA | nuclear receptor activity | localization | epithelial tube morphogenesis | negative regulation of signaling | developmental growth | reproductive system development | response to estradiol | female pregnancy | transcription factor activity, direct ligand regulated sequence-specific DNA binding | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | macromolecule localization | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of immune response | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | regulation of gene silencing by miRNA | prostate gland epithelium morphogenesis | urogenital system development | mammary gland morphogenesis | development of primary sexual characteristics | response to stimulus | gland morphogenesis | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | ovulation cycle | tube morphogenesis | epithelial cell development | development of primary female sexual characteristics | reproduction | cellular localization | androgen metabolic process | rhythmic process | regulation of gene silencing | cellular nitrogen compound metabolic process | axis elongation | cellular response to organic cyclic compound | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | regulation of morphogenesis of a branching structure | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | regulation of toll-like receptor signaling pathway | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | mammary gland development | antral ovarian follicle growth | lipid metabolic process | vagina development | regulation of hormone levels | mammary gland lobule development | regulation of gene expression | negative regulation of gene silencing by miRNA | response to lipid | branching involved in prostate gland morphogenesis | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | intracellular estrogen receptor signaling pathway | negative regulation of DNA-binding transcription factor activity | positive regulation of protein complex assembly | regulation of transcription by RNA polymerase II | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | protein localization to organelle | stem cell differentiation | cell proliferation | biosynthetic process | aromatic compound biosynthetic process | regulation of RNA polymerase II transcriptional preinitiation complex assembly | mammary gland epithelial cell proliferation | ovulation cycle process | protein localization to chromatin | response to estrogen | cell communication | regulation of cellular metabolic process | female genitalia development | cellular response to estrogen stimulus | positive regulation of cell proliferation | regulation of RNA metabolic process | genitalia development | estrogen receptor activity | positive regulation of molecular function | negative regulation of gene silencing | multicellular organism reproduction | maternal process involved in female pregnancy | development of primary male sexual characteristics | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | regulation of fibroblast proliferation | DNA-binding transcription factor activity | response to organic substance | gland development | regulation of innate immune response | tissue morphogenesis | branching morphogenesis of an epithelial tube | epithelial cell proliferation | male sex differentiation | regulation of animal organ morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | developmental growth involved in morphogenesis | branch elongation of an epithelium | metabolic process | positive regulation of DNA-templated transcription, initiation | negative regulation of I-kappaB kinase/NF-kappaB signaling | regulation of RNA biosynthetic process | prostate epithelial cord elongation | negative regulation of transcription, DNA-templated | male gonad development | cellular protein localization | regulation of gene silencing by RNA | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | mammary gland branching involved in pregnancy | mammary gland epithelium development | cellular response to steroid hormone stimulus | prostate gland morphogenesis | transcription, DNA-templated | intracellular receptor signaling pathway | morphogenesis of a branching epithelium | mammary gland alveolus development | uterus development | cellular response to estradiol stimulus | steroid metabolic process | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | protein localization | regulation of production of small RNA involved in gene silencing by RNA | hormone metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | cellular macromolecule localization | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | reproductive structure development | regulation of developmental process | developmental process | intracellular steroid hormone receptor signaling pathway | branch elongation involved in mammary gland duct branching | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | response to steroid hormone | regulation of inflammatory response | branching involved in mammary gland duct morphogenesis | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | positive regulation of transcription initiation from RNA polymerase II promoter | protein localization to chromosome | signal transduction | regulation of signaling | positive regulation of gene expression | negative regulation of production of miRNAs involved in gene silencing by miRNA | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | transcriptional preinitiation complex | protein-containing complex | protein-DNA complex | plasma membrane | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | nuclear chromatin | transcriptionally active chromatin | intracellular | membrane

PATHWAYS

PID_SMAD2_3NUCLEAR_PATHWAY | PID_HDAC_CLASSII_PATHWAY | PID_ER_NONGENOMIC_PATHWAY | PID_LKB1_PATHWAY | PID_TELOMERASE_PATHWAY | PID_ATF2_PATHWAY | PID_AP1_PATHWAY | PID_FOXM1_PATHWAY | PID_ERA_GENOMIC_PATHWAY | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | PID_HNF3A_PATHWAY | REACTOME_SIGNALING_BY_ERBB4 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

PROTEIN FAMILY

No protein families found.