QuickView for ESR2;jsessionid=0B554F1DF3682731CD496775216E9BA9;jsessionid=2E7892FCE43B0FB029F4F26EE68BCC58 (gene)

GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | lipid binding | signaling receptor binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | steroid hormone receptor activity | chromatin binding | estradiol binding | steroid hormone binding | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | promoter-specific chromatin binding | identical protein binding | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | ion binding | organic cyclic compound binding | hormone binding | transcription regulatory region sequence-specific DNA binding | estrogen receptor activity | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | estrogen response element binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transition metal ion binding | drug binding | steroid binding | metal ion binding | heterocyclic compound binding | peroxisome proliferator activated receptor binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | brain development | regulation of blood vessel diameter | positive regulation of macromolecule biosynthetic process | response to nutrient levels | cell motility | behavioral fear response | developmental process involved in reproduction | ovarian follicle development | positive regulation of apoptotic process | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | gonad development | regulation of programmed cell death | female gonad development | response to hormone | response to hydroxyisoflavone | negative regulation of neuron death | neuron migration | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | response to dexamethasone | negative regulation of RNA biosynthetic process | cell differentiation | defense response | nervous system development | response to water | response to drug | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | response to antibiotic | hormone-mediated signaling pathway | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | response to human chorionic gonadotropin | nuclear receptor activity | localization | cell maturation | negative regulation of signaling | reproductive system development | response to estradiol | transcription factor activity, direct ligand regulated sequence-specific DNA binding | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | Sertoli cell differentiation | positive regulation of nitrogen compound metabolic process | diencephalon development | response to inorganic substance | negative regulation of cellular metabolic process | regulation of behavior | tissue development | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | epithelial cell maturation involved in prostate gland development | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | prostate gland epithelium morphogenesis | urogenital system development | development of primary sexual characteristics | head development | response to stimulus | regulation of feeding behavior | metencephalon development | positive regulation of protein metabolic process | regulation of blood vessel size | gland morphogenesis | response to stress | regulation of intracellular steroid hormone receptor signaling pathway | hypothalamus development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | ovulation cycle | Sertoli cell proliferation | epithelial cell development | programmed cell death | development of primary female sexual characteristics | reproduction | response to alcohol | rhythmic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | blood circulation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | positive regulation of ERBB signaling pathway | response to ethanol | response to phenylpropanoid | regulation of nucleic acid-templated transcription | locomotion | cellular response to magnetism | apoptotic process | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | response to activity | cell migration | regulation of MAPK cascade | learning or memory | epithelial cell differentiation involved in prostate gland development | cerebellum development | hormone-mediated apoptotic signaling pathway | vagina development | regulation of phosphorylation | regulation of gene expression | response to ketone | response to lipid | nervous system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | negative regulation of smooth muscle cell proliferation | regulation of nitrogen compound metabolic process | intracellular estrogen receptor signaling pathway | positive regulation of intracellular signal transduction | response to corticosteroid | regulation of transcription by RNA polymerase II | response to magnetism | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | amygdala development | cognition | negative regulation of intracellular steroid hormone receptor signaling pathway | cell proliferation | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | hindbrain development | response to toxic substance | response to xenobiotic stimulus | cellular response to drug | response to estrogen | epithelial cell maturation | cell communication | regulation of cellular metabolic process | female genitalia development | response to testosterone | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of androgen receptor signaling pathway | limbic system development | regulation of protein phosphorylation | regulation of RNA metabolic process | regulation of tube size | genitalia development | estrogen receptor activity | apoptotic signaling pathway | response to insecticide | positive regulation of molecular function | response to genistein | multicellular organism reproduction | development of primary male sexual characteristics | multicellular organismal response to stress | fear response | negative regulation of epithelial cell proliferation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | positive regulation of protein modification process | response to organic substance | gland development | negative regulation of behavior | tissue morphogenesis | epithelial cell proliferation | male sex differentiation | response to antineoplastic agent | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | Sertoli cell development | anatomical structure development | metabolic process | negative regulation of feeding behavior | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | male gonad development | regulation of tube diameter | behavior | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | gene expression | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | regulation of phosphate metabolic process | cellular response to steroid hormone stimulus | prostate gland morphogenesis | transcription, DNA-templated | response to gonadotropin | response to bisphenol A | positive regulation of MAPK cascade | intracellular receptor signaling pathway | uterus development | estrous cycle | response to water deprivation | negative regulation of androgen receptor signaling pathway | cellular response to estradiol stimulus | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | regulation of ERBB signaling pathway | regulation of epithelial cell proliferation | positive regulation of phosphorylation | positive regulation of epidermal growth factor receptor signaling pathway | anatomical structure morphogenesis | prostate gland development | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | behavioral defense response | intracellular steroid hormone receptor signaling pathway | response to salt | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | regulation of smooth muscle cell proliferation | response to steroid hormone | negative regulation of cell death | positive regulation of blood vessel diameter | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | cytoplasm | intracellular organelle | protein-containing complex | cell projection | protein-DNA complex | plasma membrane | perikaryon | cilium | perinuclear region of cytoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane

PATHWAYS

PID_ER_NONGENOMIC_PATHWAY | PID_ERB_GENOMIC_PATHWAY | PID_ERA_GENOMIC_PATHWAY | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

PROTEIN FAMILY

Nuclear hormone receptor, ligand-binding domain | Zinc finger, nuclear hormone receptor-type | Nuclear hormone receptor | Zinc finger, NHR/GATA-type | Estrogen receptor beta, N-terminal | Oestrogen receptor/oestrogen-related receptor | Estrogen receptor beta/gamma | Nuclear hormone receptor-like domain superfamily