QuickView for EcR;jsessionid=BB78354AC07BC482EDBF0E364213B78F;jsessionid=CAF5278BB5B23116B44B69206110439F (gene)
- Gene Symbol:
- NR1H3
Bos taurus - Full name:
- nuclear receptor subfamily 1, group H, member 3
- Synonyms:
- LXRalpha
- Genomic Location:
- Chr 15: 77482206-77489355
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
MZF1_01 , IK2_01 , HNF4_01 , CEBPDELTA_Q6 , MAZ_Q6 , PU1_Q6 , TFIII_Q6 , CACBINDINGPROTEIN_Q6 , PPAR_DR1_Q2 , HNF4_DR1_Q3
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | retinoic acid receptor binding | nuclear receptor activity | cation binding | hormone receptor binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | signaling receptor binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | steroid hormone receptor activity | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | nuclear hormone receptor binding | ion binding | organic cyclic compound binding | retinoid X receptor binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transition metal ion binding | transcription coregulator activity | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | negative regulation of leukocyte activation | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | response to lipopolysaccharide | negative regulation of peptide secretion | regulation of cholesterol transport | regulation of localization | regulation of immune system process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | negative regulation of protein secretion | regulation of lipid transport | hormone-mediated signaling pathway | negative regulation of proteolysis | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | nuclear receptor activity | negative regulation of pancreatic juice secretion | positive regulation of cholesterol efflux | regulation of digestive system process | transcription factor activity, direct ligand regulated sequence-specific DNA binding | negative regulation of nucleic acid-templated transcription | negative regulation of secretion | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | negative regulation of cholesterol storage | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | regulation of peptide secretion | response to stimulus | negative regulation of protein transport | negative regulation of secretion of lysosomal enzymes | cellular nitrogen compound biosynthetic process | sterol homeostasis | cholesterol homeostasis | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | negative regulation of transport | cellular response to organic cyclic compound | regulation of protein transport | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | regulation of peptide transport | cellular biosynthetic process | regulation of lipid storage | regulation of nucleic acid-templated transcription | negative regulation of macrophage activation | cellular response to hormone stimulus | response to external biotic stimulus | nitrogen compound metabolic process | negative regulation of secretion by cell | negative regulation of cold-induced thermogenesis | lipid metabolic process | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | negative regulation of lipid storage | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | positive regulation of cholesterol transport | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | triglyceride homeostasis | positive regulation of lipid localization | regulation of macrophage activation | response to bacterium | cell communication | regulation of cellular metabolic process | negative regulation of cell activation | regulation of protein metabolic process | homeostatic process | transcription coactivator activity | regulation of RNA metabolic process | positive regulation of transport | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regulation of establishment of protein localization | response to organic substance | metabolic process | regulation of RNA biosynthetic process | regulation of body fluid levels | negative regulation of transcription, DNA-templated | chemical homeostasis | regulation of secretion | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | regulation of cell activation | regulation of protein secretion | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | negative regulation of protein metabolic process | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of nuclear receptor transcription coactivator activity | cellular macromolecule biosynthetic process | response to biotic stimulus | regulation of cholesterol efflux | acylglycerol homeostasis | negative regulation of transcription by RNA polymerase II | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of lipid transport | cellular metabolic process | cellular response to organic substance | regulation of protein localization | response to steroid hormone | regulation of inflammatory response | lipid homeostasis | response to other organism | signal transduction | positive regulation of gene expression | cellular response to lipopolysaccharide | macromolecule metabolic process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | transcription factor complex | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | intracellular
