QuickView for FDFT1;jsessionid=39A2EA10DF6587251E49AE65A487A927;jsessionid=E7B650450C2D9390D75A315F288847ED;jsessionid=6B91124304B25949E5D3FD7BCA36ABA9 (gene)
- Gene Symbol:
- Fdft1
Rattus norvegicus - Full name:
- farnesyl diphosphate farnesyl transferase 1
- Synonyms:
- squalene synthase, FPP:FPP farnesyltransferase, SQS, SS, farnesyl diphosphate farnesyltransferase, squalene synthetase
- Genomic Location:
- Chr 15: 42425336-42453390
- Description:
-
catalyzes the conversion of trans-farnesyl diphosphate to squalene; plays a role in biosynthesis of cholesterol and of isoprenoids
- Orthologs:
- Homo sapiens , Mus musculus , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
farnesyl-diphosphate farnesyltransferase activity | transferase activity, transferring alkyl or aryl (other than methyl) groups | prenyltransferase activity | farnesyltranstransferase activity | catalytic activity | transferase activity | squalene synthase activity
GO Biological Process
isoprenoid biosynthetic process | phospholipid metabolic process | sterol metabolic process | cellular process | organic cyclic compound metabolic process | steroid biosynthetic process | cellular lipid metabolic process | alcohol metabolic process | ergosterol biosynthetic process | cellular biosynthetic process | organic hydroxy compound metabolic process | phosphorus metabolic process | lipid metabolic process | organophosphate metabolic process | sterol biosynthetic process | small molecule metabolic process | biosynthetic process | cholesterol biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | metabolic process | cholesterol metabolic process | organic substance metabolic process | steroid metabolic process | farnesyl diphosphate metabolic process | isoprenoid metabolic process | cellular metabolic process | ergosterol metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
