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QuickView for FGA;jsessionid=99A47BBCFF75D02249FAB1AEC3EA0BD9;jsessionid=402932446A06BBBB90DD058EA358D6BE (gene)


Gene Symbol:
Fga Rattus norvegicus Rattus norvegicus
Full name:
fibrinogen alpha chain
Synonyms:
Ac1873, Fba5e, fibrinogen alpha chain, fibrinogen, A alpha polypeptide, fibrinogen, alpha polypeptide
Genomic Location:
Chr 2: 174737640-174753599
Description:
plays a role in blood coagulation; may be involved in liver regeneration
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Protein Names
A1L114
Q7TQ70



GO Molecular Function

structural molecule activity | cation binding | signaling receptor binding | ion binding | cell adhesion molecule binding | protein binding | metal ion binding

GO Biological Process

regulation of ERK1 and ERK2 cascade | adaptive immune response | regulation of blood vessel diameter | response to radiation | positive regulation of locomotion | positive regulation of blood circulation | response to cytokine | proteolysis | regulation of localization | cell-substrate adhesion | response to isoquinoline alkaloid | regulation of programmed cell death | response to X-ray | response to cycloheximide | defense response to other organism | response to hormone | response to hydroxyisoflavone | negative regulation of cellular process | protein processing | response to metal ion | defense response | response to growth hormone | response to drug | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | regulation of peptide hormone secretion | positive regulation of protein secretion | response to antibiotic | cellular process | response to morphine | regulation of cell motility | zymogen activation | negative regulation of signaling | response to estradiol | positive regulation of heterotypic cell-cell adhesion | hemostasis | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | induction of bacterial agglutination | response to inorganic substance | response to peptide hormone | positive regulation of vasoconstriction | negative regulation of apoptotic signaling pathway | regeneration | negative regulation of wound healing | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | hepaticobiliary system development | positive regulation of cellular protein metabolic process | cellular component organization | platelet aggregation | regulation of peptide secretion | response to stimulus | negative regulation of epithelial cell apoptotic process | positive regulation of protein metabolic process | regulation of blood vessel size | response to stress | regulation of heterotypic cell-cell adhesion | regulation of blood circulation | response to peptide | positive regulation of cell-cell adhesion | regulation of smooth muscle cell migration | response to alcohol | positive regulation of hormone secretion | cellular response to organic cyclic compound | regulation of protein transport | blood circulation | cellular component assembly | regulation of wound healing | regulation of peptide transport | regulation of cell adhesion | response to phenylpropanoid | blood coagulation | positive regulation of peptide secretion | positive regulation of exocytosis | response to nitrogen compound | cellular response to interleukin-6 | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | antibacterial humoral response | regulation of MAPK cascade | positive regulation of smooth muscle cell migration | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | wound healing | blood coagulation, fibrin clot formation | regulation of extrinsic apoptotic signaling pathway | platelet activation | blood coagulation, common pathway | positive regulation of secretion | response to ketone | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | response to ammonium ion | liver development | regulation of blood coagulation | regulation of nitrogen compound metabolic process | regulation of cell migration | protein polymerization | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of endothelial cell apoptotic process | acute-phase response | negative regulation of extrinsic apoptotic signaling pathway | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | cellular response to granulocyte colony-stimulating factor | cellular protein-containing complex assembly | protein maturation | response to toxic substance | protein activation cascade | regulation of apoptotic signaling pathway | response to xenobiotic stimulus | regulation of epithelial cell apoptotic process | fibrinolysis | negative regulation of response to wounding | response to bacterium | regulation of cellular metabolic process | liver regeneration | humoral immune response | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of locomotion | regulation of tube size | positive regulation of transport | positive regulation of peptide hormone secretion | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | coagulation | response to genistein | antimicrobial humoral response | protein-containing complex assembly | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | gland development | response to wounding | response to antineoplastic agent | regulation of intracellular signal transduction | regulation of exocytosis | response to insulin | anatomical structure development | regulation of vasoconstriction | metabolic process | regulation of body fluid levels | negative regulation of programmed cell death | regulation of tube diameter | regulation of vesicle-mediated transport | regulation of secretion | behavior | cell adhesion | immune response | organic substance metabolic process | animal organ development | gene expression | regulation of protein secretion | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | response to alkaloid | cell-cell adhesion | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | response to fungicide | regulation of response to wounding | regulation of cell communication | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | cell-matrix adhesion | response to organic cyclic compound | positive regulation of phosphorylation | response to biotic stimulus | developmental process | envenomation resulting in modulation of blood coagulation in other organism | response to thyroid hormone | negative regulation of coagulation | regulation of transport | regulation of cell-cell adhesion | innate immune response | response to organonitrogen compound | response to calcium ion | negative regulation of blood coagulation | plasminogen activation | response to anesthetic | positive regulation of metabolic process | acute inflammatory response | immune system process | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | response to interleukin-6 | negative regulation of cell death | response to ionizing radiation | homotypic cell-cell adhesion | response to other organism | positive regulation of signaling | regulation of signaling | negative regulation of endothelial cell apoptotic process | animal organ regeneration | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | external side of plasma membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | platelet alpha granule | fibrinogen complex | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | vesicle | cytoplasmic region | extracellular region | cell cortex | membrane-bounded organelle | organelle | extracellular space | cell periphery | blood microparticle | rough endoplasmic reticulum | intracellular vesicle | cell surface | intracellular | membrane