QuickView for FGG;jsessionid=A495DD3ED94381376F15BFA99E76F20A;jsessionid=E827497E8500ACF2495133EE7CD4EAF8 (gene)
- Gene Symbol:
- Fgg
Mus musculus - Full name:
- fibrinogen gamma chain
- Synonyms:
- 3010002H13Rik, AI256424, fibrinogen gamma chain, fibrinogen, gamma polypeptide
- Genomic Location:
- Chr 3: 82811818-82818971
- Description:
-
This gene encodes the gamma subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Mice lacking the encoded protein did not possess detectable amounts of plasma fibrinogen. Pregnant mice lacking the encoded protein die due to heavy bleeding during delivery. This gene is located adjacent to the genes encoding fibrinoge...
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
structural molecule activity | cation binding | signaling receptor binding | identical protein binding | ion binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein dimerization activity | metal ion binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | adaptive immune response | regulation of blood vessel diameter | positive regulation of blood circulation | proteolysis | regulation of localization | cell-substrate adhesion | regulation of programmed cell death | establishment of localization | negative regulation of cellular process | protein processing | response to metal ion | defense response | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of peptide hormone secretion | positive regulation of protein secretion | cellular process | secretion | localization | zymogen activation | protein transport | negative regulation of signaling | regulation of platelet aggregation | positive regulation of heterotypic cell-cell adhesion | macromolecule localization | hemostasis | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | response to inorganic substance | positive regulation of vasoconstriction | negative regulation of apoptotic signaling pathway | regulation of platelet activation | negative regulation of wound healing | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | platelet aggregation | regulation of peptide secretion | response to stimulus | negative regulation of epithelial cell apoptotic process | positive regulation of protein metabolic process | negative regulation of cell adhesion | regulation of blood vessel size | response to stress | regulation of heterotypic cell-cell adhesion | regulation of blood circulation | positive regulation of cell-cell adhesion | secretion by cell | positive regulation of hormone secretion | regulation of protein transport | blood circulation | cellular component assembly | regulation of wound healing | regulation of peptide transport | regulation of cell adhesion | blood coagulation | positive regulation of peptide secretion | positive regulation of exocytosis | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | wound healing | blood coagulation, fibrin clot formation | regulation of extrinsic apoptotic signaling pathway | platelet activation | positive regulation of secretion | organic substance transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of blood coagulation | regulation of nitrogen compound metabolic process | peptide transport | protein polymerization | positive regulation of intracellular signal transduction | regulation of endothelial cell apoptotic process | negative regulation of extrinsic apoptotic signaling pathway | regulation of cellular protein metabolic process | cellular protein-containing complex assembly | protein maturation | protein activation cascade | regulation of apoptotic signaling pathway | regulation of epithelial cell apoptotic process | fibrinolysis | negative regulation of response to wounding | negative regulation of cell-cell adhesion | peptide secretion | regulation of cellular metabolic process | negative regulation of cell activation | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of tube size | positive regulation of transport | positive regulation of peptide hormone secretion | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | coagulation | negative regulation of homotypic cell-cell adhesion | protein-containing complex assembly | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | regulation of homotypic cell-cell adhesion | response to wounding | regulation of intracellular signal transduction | regulation of exocytosis | regulation of vasoconstriction | metabolic process | regulation of body fluid levels | negative regulation of programmed cell death | regulation of tube diameter | amide transport | regulation of vesicle-mediated transport | regulation of secretion | cell adhesion | immune response | organic substance metabolic process | gene expression | regulation of cell activation | regulation of protein secretion | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | establishment of protein localization | cell-cell adhesion | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | regulation of response to wounding | regulation of cell communication | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | cell-matrix adhesion | protein localization | positive regulation of phosphorylation | negative regulation of coagulation | regulation of transport | regulation of cell-cell adhesion | innate immune response | response to calcium ion | negative regulation of blood coagulation | plasminogen activation | positive regulation of metabolic process | immune system process | negative regulation of platelet activation | negative regulation of platelet aggregation | regulation of protein localization | regulation of cell death | protein secretion | negative regulation of cell death | homotypic cell-cell adhesion | positive regulation of signaling | regulation of signaling | negative regulation of endothelial cell apoptotic process | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | cytoplasmic vesicle | cell | external side of plasma membrane | cytoplasm | intracellular organelle | platelet alpha granule | fibrinogen complex | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | vesicle | cytoplasmic region | extracellular region | cell cortex | membrane-bounded organelle | organelle | extracellular space | cell periphery | blood microparticle | intracellular vesicle | cell surface | intracellular | membrane
