QuickView for FYN;jsessionid=6659D6867AF419E40DB99E86E95937ED;jsessionid=48DB068966540EAD47BA9C93CD384FF2;jsessionid=0867555B5B1D7DF50E448D8B389B2C36 (gene)
- Gene Symbol:
- Fyn
Mus musculus - Full name:
- Fyn proto-oncogene
- Synonyms:
- AI448320, AW552119, tyrosine-protein kinase Fyn, Src Kinase p59, p59-Fyn, proto-oncogene c-Fyn, proto-oncogene tyrosine-protein kinase Fyn
- Genomic Location:
- Chr 10: 39089892-39285187
- Orthologs:
- Homo sapiens , Rattus norvegicus , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
ELK1_01 , MZF1_02 , CDP_01 , CDPCR3HD_01 , FOXD3_01 , MYB_Q6 , LMO2COM_02 , ETS1_B , ETS2_B , CART1_01
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
phosphatidylinositol 3-kinase binding | ephrin receptor binding | CD8 receptor binding | cation binding | alpha-tubulin binding | hormone receptor binding | G-protein coupled glutamate receptor binding | enzyme binding | protein-containing complex binding | ribonucleotide binding | disordered domain specific binding | nucleotide binding | CD4 receptor binding | signaling receptor binding | carbohydrate derivative binding | type 5 metabotropic glutamate receptor binding | catalytic activity | ion channel binding | protein domain specific binding | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | tau protein binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | peptide hormone receptor binding | purine ribonucleoside triphosphate binding | T cell receptor binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | G-protein coupled receptor binding | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | non-membrane spanning protein tyrosine kinase activity | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | growth factor receptor binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | glutamate receptor binding | small molecule binding
GO Biological Process
positive regulation of immune response | response to extracellular stimulus | brain development | adaptive immune response | cell morphogenesis | regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of cysteine-type endopeptidase activity | regulation of intracellular protein transport | heart process | response to nutrient levels | detection of stimulus | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | immune response-regulating signaling pathway | regulation of cellular localization | cellular response to platelet-derived growth factor stimulus | regulation of cell development | regulation of localization | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | regulation of cell shape | negative regulation of neuron death | neuron migration | negative regulation of cellular process | positive regulation of developmental process | regulation of protein localization to membrane | cell differentiation | immune response-activating cell surface receptor signaling pathway | T cell receptor signaling pathway | detection of mechanical stimulus involved in sensory perception | nervous system development | cellular response to extracellular stimulus | response to drug | response to glycine | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | generation of neurons | response to antibiotic | sensory perception of mechanical stimulus | regulation of neuron death | cellular process | localization | axon ensheathment | cell projection morphogenesis | negative regulation of signaling | negative regulation of synapse organization | neuron development | negative regulation of apoptotic process | regulation of proteolysis | response to growth factor | positive regulation of catalytic activity | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | negative regulation of cellular metabolic process | regulation of cell differentiation | negative regulation of apoptotic signaling pathway | activated T cell proliferation | peptidyl-tyrosine autophosphorylation | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | response to transforming growth factor beta | T cell activation | head development | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | mononuclear cell proliferation | positive regulation of phosphatidylinositol 3-kinase signaling | positive regulation of JAK-STAT cascade | positive regulation of cellular protein localization | regulation of protein ubiquitination | response to peptide | positive regulation of cysteine-type endopeptidase activity | ensheathment of neurons | response to L-glutamate | response to alcohol | positive regulation of proteolysis | immune response-activating signal transduction | regulation of protein transport | negative regulation of metabolic process | protein modification process | regulation of synapse structure or activity | regulation of peptide transport | macromolecule modification | regulation of intracellular transport | response to ethanol | negative regulation of dendritic spine maintenance | detection of abiotic stimulus | locomotion | response to nitrogen compound | negative regulation of neuron apoptotic process | regulation of calcium ion transport into cytosol | system development | cellular response to nutrient levels | nitrogen compound metabolic process | regulation of signal transduction | myelination | positive regulation of neuron projection development | multicellular organism development | cell migration | regulation of peptidase activity | phosphorus metabolic process | response to amino acid | regulation of catalytic activity | regulation of phosphorylation | detection of mechanical stimulus involved in sensory perception of pain | regulation of neuron differentiation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | nervous system process | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of protein localization to nucleus | regulation of synapse organization | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of cell projection organization | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | response to nutrient | positive regulation of hydrolase activity | positive regulation of cell differentiation | negative regulation of extrinsic apoptotic signaling pathway | response to platelet-derived growth factor | cell proliferation | leukocyte proliferation | positive regulation of protein localization to nucleus | sensory perception of pain | regulation of cellular protein metabolic process | phosphorylation | positive regulation of endopeptidase activity | regulation of calcium ion transmembrane transport | positive regulation of neuron death | response to toxic substance | regulation of apoptotic signaling pathway | cellular response to amino acid stimulus | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | cellular response to drug | cell communication | regulation of cellular metabolic process | positive regulation of protein localization to membrane | regulation of neuron apoptotic process | positive regulation of tyrosine phosphorylation of STAT protein | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of establishment of protein localization | regulation of protein phosphorylation | cellular response to glycine | negative regulation of protein ubiquitination | positive regulation of transport | lymphocyte activation | protein tyrosine kinase activity | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | neuron differentiation | activation of immune response | protein metabolic process | cellular response to nutrient | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | negative regulation of cell projection organization | regulation of JAK-STAT cascade | response to mechanical stimulus | detection of stimulus involved in sensory perception | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | cell projection organization | metabolic process | positive regulation of cell development | regulation of protein catabolic process | regulation of protein targeting | negative regulation of programmed cell death | regulation of calcium ion import across plasma membrane | positive regulation of cell death | immune response | protein kinase activity | neuron projection development | organic substance metabolic process | negative regulation of gene expression | animal organ development | forebrain development | negative regulation of cellular protein metabolic process | T cell proliferation | regulation of phosphate metabolic process | regulation of dendritic spine maintenance | regulation of ion transmembrane transport | antigen receptor-mediated signaling pathway | detection of mechanical stimulus | positive regulation of intracellular transport | regulation of postsynapse organization | cell activation | positive regulation of protein transport | dendrite morphogenesis | negative regulation of protein catabolic process | negative regulation of protein metabolic process | sensory perception | regulation of calcium ion import | lymphocyte proliferation | non-membrane spanning protein tyrosine kinase activity | regulation of cell communication | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | response to amyloid-beta | cell development | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | regulation of endopeptidase activity | dendrite development | regulation of nervous system development | regulation of developmental process | regulation of ion transport | kinase activity | developmental process | regulation of calcium ion transport | cellular protein modification process | positive regulation of protein targeting to membrane | regulation of transport | response to organonitrogen compound | regulation of glutamate receptor signaling pathway | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | cellular response to L-glutamate | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | cytoplasmic side of plasma membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | extrinsic component of membrane | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | cytoplasmic side of membrane | extrinsic component of plasma membrane | cytoplasm | intracellular organelle | actin cytoskeleton | membrane microdomain | dendritic tree | glial cell projection | cell projection | endomembrane system | postsynapse | plasma membrane | extrinsic component of cytoplasmic side of plasma membrane | membrane raft | vesicle | postsynaptic density | asymmetric synapse | mitochondrion | endosome | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cell periphery | cytosol | intracellular vesicle | actin filament | cytoskeleton | intracellular | membrane | supramolecular complex
