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QuickView for Fli-1;jsessionid=151134CBCE45DEFBCD0236A93F578AB4;jsessionid=8D91B414E76BD9F9681CEC3B57915547 (gene)


Gene Symbol:
FLII Homo sapiens Homo sapiens
Full name:
FLII, actin remodeling protein
Synonyms:
FLI, FLIL, Fli1, protein flightless-1 homolog, flightless I actin binding protein, flightless I homolog
Genomic Location:
Chr 17: 18088875-18102780
Description:
This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chro...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17p11.2





GO Molecular Function

actin binding | actin filament binding | protein-containing complex binding | cytoskeletal protein binding | protein binding

GO Biological Process

RNA metabolic process | actin filament-based process | actin cytoskeleton organization | cellular process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | actin filament severing | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | regulation of nitrogen compound metabolic process | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | cytoskeleton organization | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | organelle organization | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

brush border | intracellular membrane-bounded organelle | adherens junction | microtubule organizing center | focal adhesion | cell | nuclear lumen | cytoplasm | cell-substrate junction | intracellular organelle | nucleoplasm | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cell-substrate adherens junction | cytosol | cytoskeleton | intracellular | cell junction