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QuickView for GAD65;jsessionid=D642737D9EDD5E1769367D090DE6D195;jsessionid=4250FF5AD38254B503C332306EA0FC10;jsessionid=7140D362596C185EE1A7EBB0B3410539;jsessionid=60FDDB942DF57098B9178249E1277F8E (gene)


Gene Symbol:
Gad2 Rattus norvegicus Rattus norvegicus
Full name:
glutamate decarboxylase 2
Synonyms:
gad65, glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 2 (islet), glutamate decarboxylase 65 kDa isoform, glutamic acid decarboxylase 2, glutamic acid decarboxylase 65
Genomic Location:
Chr 17: 96259428-96321857
Description:
catalyzes synthesis of gamma-Aminobutyric acid (GABA), the most widely distributed inhibitory neurotransmitter
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012563
Protein Names
Q05683



GO Molecular Function

cofactor binding | carboxylic acid binding | vitamin binding | coenzyme binding | lyase activity | carbon-carbon lyase activity | pyridoxal phosphate binding | catalytic activity | anion binding | amino acid binding | glutamate decarboxylase activity | protein heterodimerization activity | carboxy-lyase activity | ion binding | organic cyclic compound binding | vitamin B6 binding | protein binding | protein dimerization activity | glutamate binding | drug binding | organic acid binding | heterocyclic compound binding | small molecule binding

GO Biological Process

succinate metabolic process | response to drug | cellular amino acid catabolic process | cellular process | organic substance catabolic process | dicarboxylic acid metabolic process | chemical synaptic transmission | cellular amino acid metabolic process | catabolic process | response to stimulus | dicarboxylic acid catabolic process | carboxylic acid catabolic process | cellular biosynthetic process | cell-cell signaling | regulation of neurotransmitter levels | nitrogen compound metabolic process | glutamate metabolic process | synaptic signaling | small molecule metabolic process | glutamate decarboxylation to succinate | neurotransmitter metabolic process | biosynthetic process | glutamate catabolic process | cell communication | drug metabolic process | carboxylic acid metabolic process | metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | neurotransmitter biosynthetic process | signaling | organic acid metabolic process | cellular metabolic process

GO Cellular Component

presynaptic membrane | exocytic vesicle | intracellular membrane-bounded organelle | synapse | neuron projection | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | synaptic membrane | transport vesicle membrane | cytoplasm | intracellular organelle | presynapse | Golgi apparatus | cell projection | secretory vesicle | endomembrane system | plasma membrane | exocytic vesicle membrane | vesicle | transport vesicle | perinuclear region of cytoplasm | anchored component of membrane | synaptic vesicle | Golgi membrane | membrane-bounded organelle | organelle | inhibitory synapse | vesicle membrane | cell periphery | axon | synaptic vesicle membrane | cytosol | intracellular vesicle | intracellular | cell junction | membrane | cytoplasmic vesicle membrane