QuickView for GCH1;jsessionid=6EA3B109937AA8A1EC8F77524F2605A2;jsessionid=2E0A9F74E47DBD087B6D3587DD979E58 (gene)
- Gene Symbol:
- Gch1
Mus musculus - Full name:
- GTP cyclohydrolase 1
- Synonyms:
- GTP-CH, GTPCH, Gch, GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I
- Genomic Location:
- Chr 14: 47773570-47809077
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , HNF4_01 , TATA_C , TATA_01 , E2F_Q3 , E2F1_Q3 , PPAR_DR1_Q2 , ACATTCC_MIR1_MIR206 , GTGACTT_MIR224 , ACCAAAG_MIR9
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
kinase binding | translation initiation factor binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | guanyl ribonucleotide binding | cofactor binding | ribonucleoside binding | cation binding | protein kinase binding | enzyme binding | mitogen-activated protein kinase binding | ribonucleotide binding | nucleotide binding | coenzyme binding | hydrolase activity | GTP-dependent protein binding | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | cyclohydrolase activity | protein binding | protein homodimerization activity | zinc ion binding | protein dimerization activity | GTP binding | hydrolase activity, acting on acid anhydrides | transition metal ion binding | GTP cyclohydrolase activity | nucleoside binding | calcium ion binding | purine ribonucleotide binding | GTP cyclohydrolase I activity | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding
GO Biological Process
positive regulation of heart contraction | protein homooligomerization | regulation of blood vessel diameter | positive regulation of blood circulation | regulation of serotonin biosynthetic process | response to cytokine | regulation of cellular response to oxidative stress | regulation of response to oxidative stress | response to lipopolysaccharide | catechol-containing compound metabolic process | pteridine-containing compound biosynthetic process | defense response | polyol metabolic process | phenol-containing compound metabolic process | tetrahydrofolate metabolic process | cellular process | regulation of removal of superoxide radicals | positive regulation of nitric-oxide synthase activity | positive regulation of oxidoreductase activity | positive regulation of catalytic activity | folic acid-containing compound biosynthetic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | regulation of lung blood pressure | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | folic acid-containing compound metabolic process | tetrahydrobiopterin biosynthetic process | tetrahydrofolate biosynthetic process | response to stimulus | dihydrobiopterin metabolic process | response to pain | regulation of blood vessel size | response to stress | cellular nitrogen compound biosynthetic process | alcohol metabolic process | regulation of blood circulation | regulation of heart rate | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | catecholamine biosynthetic process | blood circulation | cofactor metabolic process | cellular component assembly | cellular biosynthetic process | pteridine-containing compound metabolic process | dopamine metabolic process | negative regulation of blood pressure | regulation of cellular response to stress | regulation of neurotransmitter levels | positive regulation of monooxygenase activity | organic hydroxy compound metabolic process | regulation of superoxide metabolic process | response to external biotic stimulus | nitrogen compound metabolic process | coenzyme biosynthetic process | neuromuscular process controlling posture | protein complex oligomerization | regulation of catalytic activity | regulation of nitric-oxide synthase activity | response to lipid | nervous system process | regulation of blood pressure | cofactor biosynthetic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | cellular amide metabolic process | dopamine biosynthetic process | tetrahydrobiopterin metabolic process | biosynthetic process | diol biosynthetic process | aromatic compound biosynthetic process | regulation of heart contraction | response to bacterium | regulation of cellular metabolic process | regulation of tube size | drug metabolic process | carboxylic acid metabolic process | positive regulation of molecular function | positive regulation of heart rate | protein-containing complex assembly | multicellular organismal response to stress | response to organic substance | catecholamine metabolic process | regulation of response to reactive oxygen species | vasodilation | metabolic process | regulation of tube diameter | immune response | organic substance metabolic process | amide biosynthetic process | response to interferon-gamma | regulation of oxidoreductase activity | neuromuscular process | organic acid metabolic process | protein heterooligomerization | response to biotic stimulus | regulation of reactive oxygen species metabolic process | innate immune response | cellular modified amino acid metabolic process | heterocycle metabolic process | positive regulation of metabolic process | immune system process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | positive regulation of blood vessel diameter | response to other organism | cellular response to lipopolysaccharide | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cytoplasmic vesicle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | endomembrane system | nucleoplasm | nuclear envelope | vesicle | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular vesicle | intracellular | membrane
