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QuickView for GCLC;jsessionid=9458CF7126141EC75D74CCC3AA559853;jsessionid=5CA591CF9359CF3616ABBADB5C723DF9 (gene)


Gene Symbol:
GCLC Canis lupus familiaris Canis lupus familiaris
Full name:
glutamate-cysteine ligase, catalytic subunit
Synonyms:
N/A
Genomic Location:
Chr 12: 24003154-24050367
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Protein Names
No proteins found.



GO Molecular Function

ADP binding | cofactor binding | cation binding | magnesium ion binding | carboxylic acid binding | ribonucleotide binding | nucleotide binding | coenzyme binding | carbohydrate derivative binding | anion binding | adenyl nucleotide binding | amino acid binding | purine nucleotide binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | protein binding | protein dimerization activity | glutamate binding | purine ribonucleotide binding | adenyl ribonucleotide binding | organic acid binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

sulfur compound metabolic process | regulation of programmed cell death | response to hormone | negative regulation of cellular process | negative regulation of RNA biosynthetic process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | positive regulation of protein catabolic process | cellular process | cellular homeostasis | dicarboxylic acid metabolic process | regulation of mitochondrial membrane potential | negative regulation of signaling | serine family amino acid metabolic process | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | negative regulation of apoptotic signaling pathway | cellular amino acid metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | regulation of mitochondrial depolarization | cellular component organization | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | regulation of blood vessel size | response to stress | cell redox homeostasis | regulation of protein ubiquitination | programmed cell death | positive regulation of proteolysis involved in cellular protein catabolic process | response to temperature stimulus | positive regulation of proteolysis | apoptotic mitochondrial changes | blood circulation | negative regulation of metabolic process | cofactor metabolic process | mitochondrion organization | regulation of nucleic acid-templated transcription | regulation of membrane potential | apoptotic process | sulfur amino acid metabolic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | glutamate metabolic process | regulation of membrane depolarization | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | monosaccharide metabolic process | small molecule metabolic process | response to oxidative stress | negative regulation of extrinsic apoptotic signaling pathway | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | carbohydrate metabolic process | regulation of apoptotic signaling pathway | response to xenobiotic stimulus | regulation of cellular metabolic process | L-ascorbic acid metabolic process | regulation of protein metabolic process | homeostatic process | regulation of RNA metabolic process | negative regulation of protein ubiquitination | regulation of tube size | carboxylic acid metabolic process | regulation of proteasomal ubiquitin-dependent protein catabolic process | response to organic substance | vitamin metabolic process | metabolic process | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | regulation of proteasomal protein catabolic process | chemical homeostasis | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | response to heat | ion homeostasis | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | response to arsenic-containing substance | regulation of transcription, DNA-templated | organic acid metabolic process | cysteine metabolic process | organelle organization | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | regulation of signaling | multicellular organismal process

GO Cellular Component

cell | cytoplasm | cytosol | intracellular