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QuickView for GCN2;jsessionid=EDA9BF8F9468D4BB7E75667668C1837D;jsessionid=FD3246E2AF43801961B3ACC1101C1681 (gene)


Gene Symbol:
Eif2ak4 Rattus norvegicus Rattus norvegicus
Full name:
eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms:
eIF-2-alpha kinase GCN2, GCN2-like protein
Genomic Location:
Chr 3: 104820242-104906289
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Saccharomyces cerevisiae Danio rerio Schizosaccharomyces pombe Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene


Transcripts Names
XM_230462
XM_001074965
NM_001105744
Protein Names
No proteins found.



GO Molecular Function

nucleic acid binding | ribonucleotide binding | tRNA binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | eukaryotic translation initiation factor 2alpha kinase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | translation regulator activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding | RNA binding

GO Biological Process

positive regulation of immune response | regulation of translational initiation by eIF2 alpha phosphorylation | response to extracellular stimulus | response to radiation | cell morphogenesis | positive regulation of macromolecule biosynthetic process | response to nutrient levels | response to endoplasmic reticulum stress | long-term memory | regulation of neurogenesis | neuron projection morphogenesis | regulation of cell development | regulation of autophagy | regulation of immune system process | negative regulation of translation in response to stress | negative regulation of cellular process | cell differentiation | induction by virus of host autophagy | nervous system development | cellular response to extracellular stimulus | cell part morphogenesis | neurogenesis | generation of neurons | interaction with symbiont | neuron projection extension | positive regulation of cellular biosynthetic process | cellular process | cellular response to cold | cell projection morphogenesis | positive regulation of synaptic transmission | developmental growth | neuron development | positive regulation of adaptive immune response | negative regulation of viral life cycle | learning | endoplasmic reticulum unfolded protein response | positive regulation of defense response to virus by host | regulation of defense response to virus | cellular response to starvation | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of behavior | regulation of cell differentiation | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | negative regulation of CREB transcription factor activity | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular component organization | cellular response to topologically incorrect protein | T cell activation | response to UV | regulation of translational initiation | response to stimulus | regulation of feeding behavior | regulation of long-term synaptic potentiation | modulation by virus of host process | positive regulation of immune system process | positive regulation of protein metabolic process | response to cold | cellular response to light stimulus | response to stress | positive regulation of translational initiation in response to stress | leukocyte activation involved in immune response | posttranscriptional regulation of gene expression | positive regulation of long-term synaptic potentiation | response to starvation | protein serine/threonine kinase activity | response to temperature stimulus | negative regulation of viral genome replication | negative regulation of metabolic process | protein modification process | modulation of chemical synaptic transmission | macromolecule modification | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to light stimulus | system development | cellular response to nutrient levels | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | learning or memory | positive regulation of translational initiation in response to starvation | cellular response to DNA damage stimulus | regulation of phosphorylation | cellular response to amino acid starvation | modulation by host of viral process | regulation of neuron differentiation | regulation of gene expression | cellular response to stress | nervous system process | cell cycle | eukaryotic translation initiation factor 2alpha kinase activity | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | cellular response to radiation | protein autophosphorylation | regulation of nitrogen compound metabolic process | negative regulation of DNA-binding transcription factor activity | negative regulation of viral process | cognition | regulation of cellular protein metabolic process | phosphorylation | negative regulation by host of viral process | T cell activation involved in immune response | protein phosphorylation | phosphate-containing compound metabolic process | cellular response to UV | cell communication | regulation of cellular metabolic process | cell activation involved in immune response | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | viral process | regulation of viral process | lymphocyte activation | eiF2alpha phosphorylation in response to endoplasmic reticulum stress | positive regulation of translational initiation | neuron differentiation | protein metabolic process | response to organic substance | translation regulator activity | cell cycle arrest | negative regulation of translational initiation in response to stress | regulation of DNA-binding transcription factor activity | anatomical structure development | developmental growth involved in morphogenesis | cell projection organization | metabolic process | regulation of adaptive immune response | regulation of RNA biosynthetic process | behavior | immune response | protein kinase activity | neuron projection development | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of neuron differentiation | negative regulation of cellular protein metabolic process | negative regulation by host of viral genome replication | regulation of phosphate metabolic process | negative regulation of translation | positive regulation of autophagy | cell activation | negative regulation of cell cycle | memory | negative regulation of protein metabolic process | positive regulation of translation in response to stress | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | cell development | cellular protein metabolic process | response to unfolded protein | anatomical structure morphogenesis | regulation of translation in response to stress | regulation of nervous system development | regulation of developmental process | regulation of translation in response to endoplasmic reticulum stress | negative regulation of translational initiation | kinase activity | developmental process | cellular protein modification process | viral translation | modulation by virus of host morphology or physiology | developmental cell growth | regulation of defense response to virus by host | response to amino acid starvation | positive regulation of metabolic process | regulation of synaptic plasticity | regulation of eIF2 alpha phosphorylation by amino acid starvation | immune system process | cellular metabolic process | regulation of viral genome replication | cellular response to leucine starvation | cellular response to organic substance | DNA damage checkpoint | regulation of translation | cell cycle checkpoint | regulation of viral life cycle | negative regulation of cell development | negative regulation of cell differentiation | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of translational initiation in response to stress | regulation of phosphorus metabolic process

GO Cellular Component

cytosolic ribosome | polysome | cell | cytoplasm | intracellular organelle | ribosome | protein-containing complex | ribonucleoprotein complex | organelle | cytosol | intracellular