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QuickView for GRIA2;jsessionid=FEB761F02F75E298FB641085E860D29C;jsessionid=AF0140E90EDA7D25E0AEEF8B4C406A8F (gene)


Gene Symbol:
Gria2 Rattus norvegicus Rattus norvegicus
Full name:
glutamate ionotropic receptor AMPA type subunit 2
Synonyms:
GluA2, GluR-K2, GluR2, gluR-B, glutamate receptor 2, AMPA-selective glutamate receptor 2, glutamate receptor B, glutamate receptor, ionotropic, AMPA 2
Genomic Location:
Chr 2: 172266138-172385285
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated ca...
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_001083811
NM_017261
Protein Names
P19491
Q9R174



GO Molecular Function

transmitter-gated ion channel activity | kinase binding | neurotransmitter receptor activity | peptide binding | channel regulator activity | amyloid-beta binding | passive transmembrane transporter activity | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | molecular function regulator | protein domain specific binding | cytoskeletal protein binding | ATPase binding | kainate selective glutamate receptor activity | cation transmembrane transporter activity | amide binding | signaling receptor activity | transporter activity | identical protein binding | ion transmembrane transporter activity | AMPA glutamate receptor activity | extracellular ligand-gated ion channel activity | glutamate receptor activity | protein binding | calcium channel regulator activity | potassium channel activity | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | potassium ion transmembrane transporter activity | excitatory extracellular ligand-gated ion channel activity | extracellularly glutamate-gated ion channel activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | SNARE binding | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | PDZ domain binding | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | establishment of localization | response to metal ion | excitatory postsynaptic potential | response to antibiotic | cellular process | channel regulator activity | localization | positive regulation of synaptic transmission | passive transmembrane transporter activity | metal ion transport | chemical synaptic transmission | macromolecule localization | response to inorganic substance | regulation of cellular process | regulation of metabolic process | transmembrane transporter activity | ligand-gated ion channel activity | cellular component organization | response to stimulus | ion gated channel activity | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of membrane potential | regulation of synaptic transmission, glutamatergic | protein complex oligomerization | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | kainate selective glutamate receptor activity | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | vesicle-mediated transport | cellular potassium ion transport | response to lithium ion | ion transmembrane transporter activity | potassium ion transport | AMPA glutamate receptor activity | extracellular ligand-gated ion channel activity | protein tetramerization | response to toxic substance | cell communication | regulation of cellular metabolic process | receptor internalization | cation transmembrane transport | calcium channel regulator activity | potassium channel activity | protein-containing complex assembly | ionotropic glutamate receptor activity | import into cell | metal ion transmembrane transporter activity | cell surface receptor signaling pathway | potassium ion transmembrane transporter activity | metabolic process | endocytosis | sodium ion transmembrane transport | organic substance metabolic process | excitatory extracellular ligand-gated ion channel activity | extracellularly glutamate-gated ion channel activity | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | sodium channel activity | establishment of protein localization | cation channel activity | response to fungicide | regulation of cell communication | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | protein localization | cation transport | channel activity | glutamate receptor signaling pathway | receptor-mediated endocytosis | regulation of receptor recycling | receptor metabolic process | potassium ion transmembrane transport | ion channel activity | ion transport | cellular metabolic process | ionotropic glutamate receptor signaling pathway | substrate-specific channel activity | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

presynaptic membrane | dendritic spine | exocytic vesicle | integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | organelle membrane | postsynaptic specialization membrane | cytoplasmic vesicle | cell body | cell | neuronal cell body | plasma membrane protein complex | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | transport vesicle membrane | cytoplasm | dendrite cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | dendritic tree | presynapse | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | secretory vesicle | postsynaptic membrane | endomembrane system | neuron spine | endoplasmic reticulum membrane | postsynapse | plasma membrane bounded cell projection cytoplasm | plasma membrane | perikaryon | exocytic vesicle membrane | postsynaptic density membrane | vesicle | transport vesicle | postsynaptic density | asymmetric synapse | cytoplasmic region | site of polarized growth | integral component of postsynaptic membrane | integral component of plasma membrane | synaptic vesicle | integral component of postsynaptic density membrane | membrane-bounded organelle | dendritic shaft | organelle | postsynaptic specialization | vesicle membrane | axon terminus | cell periphery | axon | ionotropic glutamate receptor complex | transmembrane transporter complex | growth cone | neuron projection terminus | cation channel complex | ion channel complex | synaptic vesicle membrane | intracellular vesicle | cell surface | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | AMPA glutamate receptor complex | integral component of postsynaptic specialization membrane | intrinsic component of plasma membrane