QuickView for GRIN2A;jsessionid=392C44D40FCF62555F971B693FEADCE8;jsessionid=9F5AFA94B3C751D37AB19DC7A0BE8FCC (gene)
- Gene Symbol:
- Grin2a
Rattus norvegicus - Full name:
- glutamate ionotropic receptor NMDA type subunit 2A
- Synonyms:
- GluN2A, NMDAR2A, NR2A, glutamate receptor ionotropic, NMDA 2A, N-methyl D-aspartate receptor subtype 2A, N-methyl-D-aspartate receptor subunit 2A, glutamate [NMDA] receptor subunit epsilon-1, glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- Genomic Location:
- Chr 10: 5588936-6006076
- Description:
-
may play a role in synaptic transmission, learning and memory
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
transmitter-gated ion channel activity | kinase binding | ligand-gated calcium channel activity | neurotransmitter receptor activity | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | protein kinase binding | neurotransmitter binding | transmembrane signaling receptor activity | carboxylic acid binding | enzyme binding | protein-containing complex binding | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | signaling receptor binding | anion binding | ATPase binding | amino acid binding | NMDA glutamate receptor activity | cation transmembrane transporter activity | signaling receptor activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | protein heterodimerization activity | scaffold protein binding | extracellular ligand-gated ion channel activity | glutamate receptor activity | ion binding | cell adhesion molecule binding | protein binding | zinc ion binding | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | protein dimerization activity | voltage-gated cation channel activity | excitatory extracellular ligand-gated ion channel activity | extracellularly glutamate-gated ion channel activity | glutamate binding | transition metal ion binding | cation channel activity | glutamate-gated calcium ion channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | organic acid binding | metal ion binding | ion channel activity | substrate-specific channel activity | glutamate receptor binding | small molecule binding
GO Biological Process
transmitter-gated ion channel activity | brain development | response to radiation | detection of stimulus | cellular response to zinc ion | protein localization to cell periphery | intracellular signal transduction | calcium ion transmembrane import into cytosol | positive regulation of apoptotic process | cytosolic calcium ion transport | catechol-containing compound metabolic process | ligand-gated calcium channel activity | regulation of programmed cell death | hippocampus development | establishment of localization | response to metal ion | cell differentiation | excitatory postsynaptic potential | detection of mechanical stimulus involved in sensory perception | nervous system development | response to drug | cellular chemical homeostasis | neurogenesis | voltage-gated ion channel activity | response to antibiotic | sensory perception of mechanical stimulus | phenol-containing compound metabolic process | positive regulation of neurological system process | cellular process | response to magnesium ion | localization | cellular homeostasis | positive regulation of synaptic transmission | passive transmembrane transporter activity | metal ion transport | visual learning | chemical synaptic transmission | regulation of neuronal synaptic plasticity | learning | macromolecule localization | protein localization to postsynaptic membrane | response to growth factor | response to inorganic substance | establishment of localization in cell | regulation of neurological system process | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | organic cyclic compound metabolic process | ligand-gated ion channel activity | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | cellular component organization | calcium ion homeostasis | cellular response to metal ion | head development | calcium ion transport into cytosol | associative learning | response to stimulus | serotonin metabolic process | ion gated channel activity | regulation of long-term synaptic potentiation | response to cocaine | response to stress | response to peptide | positive regulation of long-term synaptic potentiation | cellular response to inorganic substance | cellular localization | divalent metal ion transport | response to alcohol | rhythmic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | dopamine metabolic process | cell surface receptor signaling pathway involved in cell-cell signaling | metal ion homeostasis | response to ethanol | regulation of membrane potential | detection of abiotic stimulus | regulation of neurotransmitter levels | locomotion | organic hydroxy compound metabolic process | response to nitrogen compound | regulation of long-term neuronal synaptic plasticity | response to light stimulus | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | modulation of excitatory postsynaptic potential | multicellular organism development | calcium ion transmembrane transport | response to amino acid | learning or memory | response to dsRNA | protein complex oligomerization | response to methylmercury | ion transmembrane transport | regulation of sensory perception of pain | telencephalon development | detection of mechanical stimulus involved in sensory perception of pain | regulation of postsynaptic membrane potential | protein localization to membrane | response to lipid | nervous system process | cellular response to peptide | synaptic signaling | NMDA glutamate receptor activity | cation transmembrane transporter activity | cellular ion homeostasis | sleep | response to manganese ion | response to ammonium ion | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | cognition | neurotransmitter metabolic process | sensory perception of pain | extracellular ligand-gated ion channel activity | startle response | protein tetramerization | response to toxic substance | response to xenobiotic stimulus | cellular response to amino acid stimulus | cation homeostasis | protein localization to synapse | cellular cation homeostasis | cell communication | cellular response to amyloid-beta | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | cellular response to dsRNA | homeostatic process | limbic system development | response to zinc ion | cerebral cortex development | drug metabolic process | calcium-mediated signaling | cation transmembrane transport | protein-containing complex assembly | response to organic substance | visual behavior | ionotropic glutamate receptor activity | catecholamine metabolic process | response to wounding | response to mechanical stimulus | detection of stimulus involved in sensory perception | metal ion transmembrane transporter activity | anatomical structure development | response to amine | cell surface receptor signaling pathway | voltage-gated cation channel activity | metabolic process | directional locomotion | regulation of protein catabolic process | cellular protein localization | chemical homeostasis | calcium ion transport | behavior | positive regulation of cell death | organic substance metabolic process | animal organ development | forebrain development | excitatory extracellular ligand-gated ion channel activity | pallium development | extracellularly glutamate-gated ion channel activity | positive regulation of programmed cell death | ion homeostasis | inorganic cation transmembrane transport | response to alkaloid | detection of mechanical stimulus | positive regulation of excitatory postsynaptic potential | cation channel activity | memory | negative regulation of protein catabolic process | negative regulation of protein metabolic process | sensory perception | response to fungicide | regulation of cell communication | transmembrane transport | action potential | glutamate-gated calcium ion channel activity | signaling | inorganic cation transmembrane transporter activity | response to amyloid-beta | response to organic cyclic compound | neuromuscular process | protein localization | voltage-gated channel activity | cation transport | cellular macromolecule localization | channel activity | glutamate receptor signaling pathway | response to biotic stimulus | developmental process | calcium channel activity | cellular response to manganese ion | response to organonitrogen compound | cellular metal ion homeostasis | heterocycle metabolic process | response to calcium ion | central nervous system development | ion channel activity | response to anesthetic | spinal cord development | regulation of synaptic plasticity | response to amphetamine | ion transport | cellular metabolic process | long-term synaptic potentiation | cellular response to organic substance | regulation of cell death | response to carbohydrate | ionotropic glutamate receptor signaling pathway | divalent inorganic cation homeostasis | substrate-specific channel activity | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | multicellular organismal process | cellular response to magnesium ion
GO Cellular Component
presynaptic membrane | dendritic spine | exocytic vesicle | integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | postsynaptic specialization membrane | cytoplasmic vesicle | cell | plasma membrane protein complex | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | cytoplasm | intracellular organelle | NMDA selective glutamate receptor complex | receptor complex | endoplasmic reticulum | dendritic tree | presynapse | protein-containing complex | cell projection | secretory vesicle | postsynaptic membrane | endomembrane system | neuron spine | postsynapse | plasma membrane | postsynaptic density membrane | vesicle | transport vesicle | postsynaptic density | asymmetric synapse | integral component of postsynaptic membrane | integral component of plasma membrane | synaptic vesicle | integral component of postsynaptic density membrane | membrane-bounded organelle | organelle | postsynaptic specialization | axon terminus | cell periphery | axon | ionotropic glutamate receptor complex | transmembrane transporter complex | neuron projection terminus | cation channel complex | ion channel complex | intracellular vesicle | cell surface | intracellular | cell junction | membrane | integral component of postsynaptic specialization membrane | intrinsic component of plasma membrane
