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QuickView for Gja1;jsessionid=F04D5EAE79C76B2271C8D702C236C8BB;jsessionid=D27482472257090C08B38EA8203F16D7 (gene)


Gene Symbol:
Gja1 Mus musculus Mus musculus
Full name:
gap junction protein, alpha 1
Synonyms:
AU042049, AW546267, Cnx43, Cx43, Cx43alpha1, Gja-1, Npm1, connexin43, gap junction alpha-1 protein, alpha 1 connexin, connexin-43, gap junction 43 kDa heart protein, gap junction membrane channel protein alpha 1
Genomic Location:
Chr 10: 56097153-56110224
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):


Transcripts Names
NM_010288
Protein Names
Q8C4N2
P23242
Q544I7



GO Molecular Function

kinase binding | gap junction channel activity involved in cell communication by electrical coupling | passive transmembrane transporter activity | gap junction channel activity involved in cardiac conduction electrical coupling | protein kinase binding | enzyme binding | disordered domain specific binding | transmembrane transporter activity | SH3 domain binding | signaling receptor binding | gap junction channel activity | beta-tubulin binding | protein domain specific binding | cytoskeletal protein binding | transporter activity | ion transmembrane transporter activity | scaffold protein binding | protein tyrosine kinase binding | protein binding | wide pore channel activity | connexin binding | PDZ domain binding | tubulin binding | channel activity

GO Biological Process

limb development | regulation of blood vessel diameter | cell morphogenesis | reflex | regulation of ventricular cardiac muscle cell membrane repolarization | positive regulation of blood circulation | positive regulation of behavior | cell motility | neuron projection morphogenesis | purine nucleotide transport | regulation of localization | gap junction channel activity involved in cell communication by electrical coupling | morphogenesis of an epithelium | positive regulation of striated muscle tissue development | regulation of ventricular cardiac muscle cell membrane depolarization | eye development | establishment of localization | neuron migration | negative regulation of cellular process | positive regulation of developmental process | embryonic appendage morphogenesis | regulation of heart growth | cell differentiation | defense response | positive regulation of cell communication by chemical coupling | negative regulation of organ growth | nervous system development | epithelial to mesenchymal transition | positive regulation of protein catabolic process | response to drug | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | regulation of peptide hormone secretion | generation of neurons | positive regulation of protein secretion | mesenchyme development | negative regulation of DNA metabolic process | blood vessel morphogenesis | regulation of bone remodeling | regulation of cardiac muscle cell proliferation | pattern specification process | cellular process | negative regulation of DNA biosynthetic process | secretion | negative regulation of muscle organ development | localization | cellular homeostasis | cell projection morphogenesis | epithelial tube morphogenesis | limb morphogenesis | cell maturation | tissue remodeling | heart morphogenesis | passive transmembrane transporter activity | developmental growth | neuron development | negative regulation of developmental growth | determination of left/right symmetry | gap junction channel activity involved in cardiac conduction electrical coupling | cell communication by chemical coupling | anion transport | regulation of striated muscle tissue development | positive regulation of nitrogen compound metabolic process | epicardial cell to mesenchymal cell transition | regulation of fear response | negative regulation of cellular metabolic process | regulation of bone mineralization | regulation of behavior | tissue development | regulation of cell differentiation | positive regulation of vasoconstriction | regeneration | negative regulation of wound healing | regulation of cellular process | regulation of osteoblast differentiation | regulation of metabolic process | regulation of cytosolic calcium ion concentration | regulation of bicellular tight junction assembly | regulation of blood vessel remodeling | transmembrane transporter activity | purine ribonucleotide transport | epithelium development | establishment of cell polarity | cellular component organization | calcium ion homeostasis | negative regulation of cardiac muscle tissue development | regulation of peptide secretion | response to stimulus | vasculature development | embryonic limb morphogenesis | positive regulation of cold-induced thermogenesis | regulation of insulin secretion | positive regulation of protein metabolic process | regulation of blood vessel size | determination of heart left/right asymmetry | response to stress | regulation of cell proliferation | tube morphogenesis | regulation of blood circulation | epithelial cell development | positive regulation of behavioral fear response | programmed cell death | gap junction channel activity | cardiovascular system development | positive regulation of hormone secretion | negative regulation of muscle tissue development | regulation of protein transport | blood circulation | vascular transport | negative regulation of metabolic process | cellular component assembly | regulation of wound healing | regulation of peptide transport | embryo development | response to pH | cell-cell signaling | metal ion homeostasis | cell communication by electrical coupling | blood vessel development | positive regulation of peptide secretion | regulation of membrane potential | locomotion | apoptotic process | atrial ventricular junction remodeling | system development | negative regulation of growth | multicellular organism development | cell migration | mammary gland development | protein complex oligomerization | positive regulation of muscle organ development | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | regulation of ossification | wound healing | determination of bilateral symmetry | regulation of gene expression | cellular response to pH | positive regulation of secretion | organic substance transport | regulation of behavioral fear response | regulation of blood pressure | regulation of membrane depolarization | embryonic heart tube morphogenesis | regulation of systemic arterial blood pressure | cellular ion homeostasis | animal organ morphogenesis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | ion transmembrane transporter activity | positive regulation of cell differentiation | ATP transport | milk ejection reflex | regulation of glomerular filtration | positive regulation of ossification | organic anion transport | cell communication by electrical coupling involved in cardiac conduction | heart looping | regulation of heart contraction | positive regulation of glomerular filtration | cation homeostasis | establishment or maintenance of cell polarity | sensory organ development | negative regulation of response to wounding | chordate embryonic development | negative regulation of cardiac muscle cell proliferation | epithelial cell maturation | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | adenine nucleotide transport | regulation of atrial cardiac muscle cell membrane depolarization | inflammatory response | regulation of protein metabolic process | negative regulation of striated muscle tissue development | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of establishment of protein localization | embryo development ending in birth or egg hatching | regulation of tube size | positive regulation of transport | positive regulation of peptide hormone secretion | negative regulation of cell growth | embryonic morphogenesis | positive regulation of osteoblast differentiation | neuron differentiation | embryonic organ morphogenesis | chronic inflammatory response | protein-containing complex assembly | negative regulation of epithelial cell proliferation | regulation of establishment of protein localization | regulation of growth | gland development | regulation of cardiac muscle tissue development | positive regulation of insulin secretion | tissue morphogenesis | wide pore channel activity | lactation | response to wounding | embryonic heart tube development | anatomical structure development | nucleobase-containing compound transport | regulation of vasoconstriction | cell projection organization | mesenchymal cell differentiation | regulation of protein catabolic process | developmental maturation | regulation of body fluid levels | embryonic organ development | regulation of tube diameter | cell communication involved in cardiac conduction | regulation of tissue remodeling | negative regulation of endothelial cell proliferation | chemical homeostasis | regulation of secretion | body fluid secretion | neuron projection development | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of endothelial cell proliferation | establishment of epithelial cell polarity | regulation of protein secretion | ion homeostasis | regulation of ion transmembrane transport | renal system process | positive regulation of muscle tissue development | drug transport | positive regulation of protein transport | camera-type eye development | skeletal muscle tissue regeneration | regulation of response to wounding | regulation of cell communication | transmembrane transport | signaling | cell development | embryonic digit morphogenesis | regulation of developmental growth | regulation of transmembrane transporter activity | regulation of epithelial cell proliferation | anatomical structure morphogenesis | channel activity | regulation of organ growth | regulation of developmental process | regulation of ion transport | renal system process involved in regulation of systemic arterial blood pressure | developmental process | regulation of DNA biosynthetic process | regulation of cell growth | regulation of calcium ion transport | tube development | regulation of cell junction assembly | regulation of transport | negative regulation of cell proliferation | cellular metal ion homeostasis | epithelial cell differentiation | in utero embryonic development | positive regulation of metabolic process | ossification | osteoblast differentiation | ion transport | regulation of protein localization | adult heart development | positive regulation of blood vessel diameter | circulatory system development | divalent inorganic cation homeostasis | tissue regeneration | regulation of membrane repolarization | regulation of cellular component organization | lens development in camera-type eye | positive regulation of signaling | signal transduction | carbohydrate derivative transport | regulation of signaling | cardiac conduction | positive regulation of gene expression | regulation of muscle organ development | multicellular organismal process | cell-cell junction organization

GO Cellular Component

intermediate filament | supramolecular fiber | intercalated disc | integral component of membrane | intracellular membrane-bounded organelle | late endosome | apical plasma membrane | adherens junction | organelle membrane | cytoplasmic vesicle | fascia adherens | cell | organelle outer membrane | nuclear lumen | multivesicular body | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | intermediate filament cytoskeleton | contractile fiber | apical part of cell | cell-cell adherens junction | cell-cell junction | cell-cell contact zone | Golgi apparatus | protein-containing complex | connexin complex | endomembrane system | nucleoplasm | plasma membrane | membrane raft | vacuole | vesicle | mitochondrion | lytic vacuole | gap junction | endosome | membrane-bounded organelle | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | lysosome | cell periphery | membrane-enclosed lumen | early endosome | outer membrane | mitochondrial membrane | cytosol | intracellular vesicle | cytoskeleton | intracellular | cell junction | lateral plasma membrane | membrane | supramolecular complex