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QuickView for HMGCR;jsessionid=8DD779B14189DD980B65EABCC858734C;jsessionid=D1D7702740D3A114CF7B12175B62212F (gene)


Gene Symbol:
HMGCR Canis lupus familiaris Canis lupus familiaris
Full name:
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms:
N/A
Genomic Location:
Chr 3: 33855410-33872950
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Gallus gallus Bos taurus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | nucleotide binding | coenzyme binding | catalytic activity | anion binding | ion binding | organic cyclic compound binding | hydroxymethylglutaryl-CoA reductase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | NADPH binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

negative regulation of phosphorylation | purine ribonucleotide metabolic process | response to radiation | negative regulation of MAPK cascade | oxidoreductase activity, acting on CH-OH group of donors | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | negative regulation of protein phosphorylation | sterol metabolic process | cellular process | nucleotide metabolic process | negative regulation of signaling | visual learning | ribose phosphate metabolic process | learning | ribonucleotide metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | steroid biosynthetic process | cellular component organization | associative learning | response to stimulus | purine nucleotide metabolic process | negative regulation of protein kinase activity | alcohol metabolic process | coenzyme A metabolic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cofactor metabolic process | cellular component assembly | organic hydroxy compound metabolic process | response to light stimulus | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | phosphorus metabolic process | learning or memory | protein complex oligomerization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | nervous system process | organophosphate metabolic process | sterol biosynthetic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | negative regulation of protein serine/threonine kinase activity | nucleobase-containing small molecule metabolic process | cognition | biosynthetic process | cholesterol biosynthetic process | regulation of cellular protein metabolic process | lipid biosynthetic process | protein tetramerization | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | negative regulation of MAP kinase activity | hydroxymethylglutaryl-CoA reductase activity | protein-containing complex assembly | visual behavior | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | cholesterol metabolic process | oxidation-reduction process | behavior | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | negative regulation of protein metabolic process | steroid metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | intrinsic component of membrane | membrane